Publications by authors named "Sarvind Tripathi"

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Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein pocket domain.
Anthony Castro, Alfredo Ruiz Rivera, Chad C Moorman, Emma R Wolf-Saxon, Hailey N Mims, Sarvind Tripathi

J Biol Chem· March 2025

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Isoform-specific C-terminal phosphorylation drives autoinhibition of Casein kinase 1.
Rachel L Harold, Nikhil K Tulsian, Rajesh Narasimamurthy, Noelle Yaitanes, Maria G Ayala Hernandez, Sarvind M Tripathi

Proc Natl Acad Sci U S A· October 2024

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Isoform-specific C-terminal phosphorylation drives autoinhibition of Casein Kinase 1.
Rachel L Harold, Nikhil K Tulsian, Rajesh Narasimamurthy, Noelle Yaitanes, Maria G Ayala Hernandez, Sarvind M Tripathi

bioRxiv· July 2024

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Clock gene homologs lin-42 and kin-20 regulate circadian rhythms in C. elegans.
Melisa L Lamberti, Rebecca K Spangler, Victoria Cerdeira, Myriam Ares, Lise Rivollet, Sarvind Tripathi

Sci Rep· June 2024

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Regulation of the circadian clock in by clock gene homologs and .
Melisa L Lamberti, Rebecca K Spangler, Victoria Cerdeira, Myriam Ares, Lise Rivollet, Sarvind Tripathi

bioRxiv· December 2023

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Targeting of intracellular oncoproteins with peptide-centric CARs.
Mark Yarmarkovich, Quinlen F Marshall, John M Warrington, Rasika Premaratne, Alvin Farrel, Sarvind Tripathi

Nature· November 2023

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Retraction Note: Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Mark Yarmarkovich, Quinlen F Marshall, John M Warrington, Rasika Premaratne, Alvin Farrel, Sarvind Tripathi

Nature· November 2023

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DNA-Encoded Macrocyclic Peptide Libraries Enable the Discovery of a Neutral MDM2-p53 Inhibitor.
Anthony P Silvestri, Qi Zhang, Yan Ping, Erik W Muir, Jingsi Zhao, Sarvind Tripathi

ACS Med Chem Lett· June 2023

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PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period.
Jonathan M Philpott, Alfred M Freeberg, Jiyoung Park, Kwangjun Lee, Clarisse G Ricci, Sarvind Tripathi

Mol Cell· May 2023

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Biolayer Interferometry Assay for Cyclin-Dependent Kinase-Cyclin Association Reveals Diverse Effects of Cdk2 Inhibitors on Cyclin Binding Kinetics.
Carrie S Tambo, Sarvind Tripathi, B Gayani K Perera, Dustin J Maly, Alexander J Bridges

ACS Chem Biol· February 2023

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Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with the retinoblastoma protein family.
Sivasankar Putta, Lucia Alvarez, Stephan Lüdtke, Peter Sehr, Gerd A Müller, Sarvind Tripathi

Structure· September 2022

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Structural Insights on the Conversion of Cytochrome P450 to P420.
Jessica A Gable, Sarvind Tripathi, Thomas L Poulos

ACS Omega· June 2022

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The MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes.
Anushweta Asthana, Parameshwaran Ramanan, Alexander Hirschi, Keelan Z Guiley, Tilini U Wijeratne, Sarvind Tripathi

Nat Commun· January 2022

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Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Mark Yarmarkovich, Quinlen F Marshall, John M Warrington, Rasika Premaratne, Alvin Farrel, Sarvind Tripathi

Nature· November 2021

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Reconstitution of an intact clock reveals mechanisms of circadian timekeeping.
Archana G Chavan, Jeffrey A Swan, Joel Heisler, Cigdem Sancar, Dustin C Ernst, Sarvind Tripathi

Science· October 2021

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Docking and mutagenesis studies lead to improved inhibitor development of ML355 for human platelet 12-lipoxygenase.
Wan-Chen Tsai, Ansari M Aleem, Jennyfer Tena, Mirella Rivera-Velazquez, Harman Singh Brah, Sarvind Tripathi

Bioorg Med Chem· September 2021

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A tyrosine phosphoregulatory system controls exopolysaccharide biosynthesis and biofilm formation in Vibrio cholerae.
Carmen Schwechheimer, Kassidy Hebert, Sarvind Tripathi, Praveen K Singh, Kyle A Floyd

PLoS Pathog· August 2020

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A long lost key opens an ancient lock: Myb causes a synthetic multivulval phenotype in nematodes.
Paul J Vorster, Paul Goetsch, Tilini U Wijeratne, Keelan Z Guiley, Laura Andrejka, Sarvind Tripathi

Biol Open· May 2020

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Casein kinase 1 dynamics underlie substrate selectivity and the PER2 circadian phosphoswitch.
Jonathan M Philpott, Rajesh Narasimamurthy, Clarisse G Ricci, Alfred M Freeberg, Sabrina R Hunt, Sarvind Tripathi

Elife· February 2020

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Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing.
Jennifer L Fribourgh, Ashutosh Srivastava, Colby R Sandate, Alicia K Michael, Peter L Hsu, Sarvind Tripathi

Elife· February 2020

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Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection.
Andrew C McShan, Christine A Devlin, Sarah A Overall, Jihye Park, Jugmohit S Toor, Sarvind Tripathi

Proc Natl Acad Sci U S A· December 2019

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p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition.
Keelan Z Guiley, Jack W Stevenson, Kevin Lou, Krister J Barkovich, Vishnu Kumarasamy, Sarvind Tripathi

Science· December 2019

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Ligand and Redox Partner Binding Generates a New Conformational State in Cytochrome P450cam (CYP101A1).
Alec H Follmer, Sarvind Tripathi, Thomas L Poulos

J Am Chem Soc· February 2019

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Structural mechanism of Myb-MuvB assembly.
Keelan Z Guiley, Audra N Iness, Siddharth Saini, Sarvind Tripathi, Joseph S Lipsick

Proc Natl Acad Sci U S A· October 2018

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Testing the N-Terminal Velcro Model of CooA Carbon Monoxide Activation.
Sarvind Tripathi, Thomas L Poulos

Biochemistry· May 2018

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