Publications by authors named "Sasha A Singh"

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Nutrient supplementation mitigates retinal dysfunction in Acox1 knockout mice with impaired peroxisomal fatty acid oxidation.
Myriam Boeck, Hitomi Yagi, Chuck T Chen, Yan Zeng, Deokho Lee, Sasha A Singh

J Adv Res· December 2025

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Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction.
Aeron M Small, Ta-Yu Yang, Shinsuke Itoh, Sébastien Thériault, Line Dufresne, Sasha A Singh

Nat Genet· December 2025

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Short- and Long-Term Effects of Pulsed Ultrasound Cavitation Therapy of Calcified Valvular Interstitial Cells in Culture.
Cassandra L Clift, Guillaume Goudot, Gabrielle Bogut, Taku Kasai, Antonia van Kampen, Sasha A Singh

Ultrasound Med Biol· November 2025

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ADP-Ribosylation in Experimental Atherosclerosis: A Potential Link Between Dyslipidemia and Inflammation in Cardiovascular Disease.
Diego V Santinelli-Pestana, Constance Delwarde, Taku Kasai, Shiori Kuraoka, Yuto Nakamura, Sasha A Singh

Arterioscler Thromb Vasc Biol· November 2025

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A systems approach to target discovery identifies the role of lncRNA-SPANXA2-OT1 in macrophage chemotaxis.
Prabhash K Jha, Sarvesh Chelvanambi, Yuto Nakamura, Lucas Yu Itto, Aatira Vijay, Sasha A Singh

JCI Insight· November 2025

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Sexual Dimorphism of Plasma and Tissue Proteomes in Human Calcific Aortic Valve Stenosis Pathogenesis-Brief Report.
Cassandra L Clift, Mark C Blaser, Francesca Bartoli-Leonard, Florian Schlotter, Hideyuki Higashi, Sasha A Singh

Arterioscler Thromb Vasc Biol· October 2025

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Precision cardiovascular medicine: shifting the innovation paradigm.
Masanori Aikawa, Abhijeet R Sonawane, Sarvesh Chelvanambi, Takaharu Asano, Arda Halu, Sasha A Singh

Front Sci· October 2025

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Combined dietary omega-3 and omega-6 fatty acids protect against hyperglycemia-associated retinopathy in neonatal mice.
Myriam Boeck, Hitomi Yagi, Pia Lundgren, Aldina Pivodic, Anders K Nilsson, Sasha A Singh

Pharmacol Res· September 2025

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Translational insights into statin-induced myotoxicity: Differential impact of lipophilic and hydrophilic statins on iPSC-derived skeletal muscle cells from patients with familial hypercholesterolemia.
Raul Hernandes Bortolin, Felipe de Souza Leite, Andre Ducati Luchessi, Joyce Esposito, Igor Neves Barbosa, Sasha Anna Singh

Toxicology· August 2025

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Antisense Oligonucleotide Targeting Sortilin Reduces Vascular Calcification in Mice in a Sex-Dependent Manner.
Adrien Lupieri, Dakota Becker-Greene, Thanh-Dat Le, Marina M Roschel, Prabhash K Jha, Sasha A Singh

Arterioscler Thromb Vasc Biol· August 2025

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Nanoparticle-enabled plasma proteomics of a mouse atherosclerosis model.
Constance Delwarde, Joan T Matamalas, Sarvesh Chelvanambi, Taku Kasai, Gabriel Shlayen, Sasha A Singh

bioRxiv· August 2025

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Multiomic Landscape of Extracellular Vesicles in Human Carotid Atherosclerotic Plaque Reveals Endothelial Communication Networks.
Sneha Raju, Mandy E Turner, Christian Cao, Majed Abdul-Samad, Neil Punwasi, Sasha A Singh

Arterioscler Thromb Vasc Biol· July 2025

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Alternative preservation strategies of DCD hearts: Effect of cold ischemia time before normothermic machine perfusion.
Manuela Lopera Higuita, Emmanuella O Ajenu, Maya Bolger-Chen, George Olverson, Soheila Ali Akbari Ghavimi, Sasha A Singh

medRxiv· June 2025

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Cross-species proteomics quantification pipeline distinguishes donor versus host extracellular matrix in explanted biomaterials.
Rachel M E Cahalane, Bart Meuris, Joan T Matamalas, Mark C Blaser, Marie Billaud, Sasha A Singh

bioRxiv· June 2025

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Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regression.
Dominique M Boucher, Sabrina Robichaud, Victoria Lorant, Jonathan S Leon, Issraa Suliman, Sasha A Singh

Arterioscler Thromb Vasc Biol· April 2025

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ApoM-bound S1P acts via endothelial S1PR1 to suppress choroidal neovascularization and vascular leakage.
Bongnam Jung, Hitomi Yagi, Andrew Kuo, Tim F Dorweiler, Masanori Aikawa, Sasha A Singh

Angiogenesis· April 2025

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Serine supplementation suppresses hypoxia-induced pathological retinal angiogenesis.
Hitomi Yagi, Chenxi Qiu, Yan Zeng, Myriam Boeck, Shen Nian, Sasha A Singh

Theranostics· April 2025

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In-Source Collision-Induced Dissociation (CID) Improves Higher-Energy Collisional Dissociation (HCD)-Dependent Fragmentation of ADP-Ribosyl Peptides.
Taku Kasai, Yuto Nakamura, Masanori Aikawa, Sasha A Singh

Rapid Commun Mass Spectrom· February 2025

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Integrative analysis of miRNAs and proteins in plasma extracellular vesicles of patients with familial hypercholesterolemia.
Renata Caroline Costa de Freitas, Raul Hernandes Bortolin, Shiori Kuraoka, Maximillian A Rogers, Mark C Blaser, Sasha A Singh

Clin Chim Acta· February 2025

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Integrating pharmacogenomics and cheminformatics with diverse disease phenotypes for cell type-guided drug discovery.
Arda Halu, Sarvesh Chelvanambi, Julius L Decano, Joan T Matamalas, Mary Whelan, Sasha A Singh

Genome Med· January 2025

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Mitochondrial control of hypoxia-induced pathological retinal angiogenesis.
Hitomi Yagi, Myriam Boeck, Shen Nian, Katherine Neilsen, Chaomei Wang, Sasha A Singh

Angiogenesis· November 2024

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Timed topical dexamethasone eye drops improve mitochondrial function to prevent severe retinopathy of prematurity.
Hitomi Yagi, Myriam Boeck, Mariya Petrishka-Lozenska, Pia Lundgren, Taku Kasai, Sasha A Singh

Angiogenesis· November 2024

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Correction: Mitochondrial control of hypoxia-induced pathological retinal angiogenesis.
Hitomi Yagi, Myriam Boeck, Shen Nian, Katherine Neilsen, Chaomei Wang, Sasha A Singh

Angiogenesis· November 2024

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Multiomics unveils extracellular vesicle-driven mechanisms of endothelial communication in human carotid atherosclerosis.
Sneha Raju, Mandy E Turner, Christian Cao, Majed Abdul-Samad, Neil Punwasi, Sasha A Singh

bioRxiv· July 2024

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Carnitine O-octanoyltransferase (CROT) deficiency in mice leads to an increase of omega-3 fatty acids.
Takehito Okui, Shiori Kuraoka, Masaya Iwashita, Rei Itagawa, Taku Kasai, Sasha A Singh

Front Mol Biosci· July 2024

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