Publications by authors named "Satoshi Akiba"

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Preventing Differentiation Towards Primitive Macrophages in Stem Cells With Down Syndrome.
Koki Harada, Keiichi Ishihara, Sayaka Wakayama, Teruhiko Wakayama, Sae Yamamoto, Satoshi Akiba

Immunology· November 2025

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Radioimaging Foam Cells Infiltrating Atherosclerotic Plaques in Mice Using I-labeled oxLDL as a Radiotracer.
Michi Izawa, Hidekazu Kawashima, Yui Okuno, Junna Nakaya, Mayuko Takeda, Satoshi Akiba

Mol Imaging Biol· December 2024

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Group IVA Phospholipase A in Collagen-Producing Cells Promotes High-Fat Diet-Induced Infiltration of Inflammatory Cells into the Liver by Upregulating the Expression of MCP-1.
Saki Kishinaka, Eri Kawashita, Taichi Nishizaki, Keiichi Ishihara, Satoshi Akiba

Biol Pharm Bull· June 2024

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Suppression of -induced Gliomagenicity in Ts1Cje Mice, a Model of Down Syndrome.
Keiichi Ishihara, Ryuto Sakoda, Masako Mizoguchi, Mitsugu Fujita, Chiami Moyama, Satoshi Akiba

Anticancer Res· February 2024

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Bio-Metal Dyshomeostasis-Associated Acceleration of Aging and Cognitive Decline in Down Syndrome.
Keiichi Ishihara, Eri Kawashita, Satoshi Akiba

Biol Pharm Bull· September 2023

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Deficiency of Group IVA Phospholipase A in Collagen-Producing Cells Alleviates the Aggravated Hepatic Fibrosis in High-Fat Diet-Fed Mice after Returning to a Normal Diet.
Takeyoshi Ozaki, Eri Kawashita, Keiichi Ishihara, Satoshi Akiba

Biol Pharm Bull· March 2023

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Plantainoside B in Bacopa monniera Binds to Aβ Aggregates Attenuating Neuronal Damage and Memory Deficits Induced by Aβ.
Aina Fukuda, Souichi Nakashima, Yoshimi Oda, Kaneyasu Nishimura, Hidekazu Kawashima, Satoshi Akiba

Biol Pharm Bull· February 2023

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Endothelial group IVA phospholipase A promotes hepatic fibrosis with sinusoidal capillarization in the early stage of non-alcoholic steatohepatitis in mice.
Eri Kawashita, Takeyoshi Ozaki, Keiichi Ishihara, Chihiro Kashiwada, Satoshi Akiba

Life Sci· April 2022

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Decrease in the T-box1 gene expression in embryonic brain and adult hippocampus of down syndrome mouse models.
Ryohei Shimizu, Keiichi Ishihara, Eri Kawashita, Haruhiko Sago, Kazuhiro Yamakawa, Satoshi Akiba

Biochem Biophys Res Commun· January 2021

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α2-Antiplasmin as a potential regulator of the spatial memory process and age-related cognitive decline.
Eri Kawashita, Keiichi Ishihara, Haruko Miyaji, Yu Tanishima, Akiko Kiriyama, Satoshi Akiba

Mol Brain· October 2020

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[Inhibition of Group IVA Phospholipase A as a Novel Therapeutic Strategy for Nonalcoholic Steatohepatitis].
Satoshi Akiba, Eri Kawashita, Keiichi Ishihara

Yakugaku Zasshi· February 2020

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Perturbation of the immune cells and prenatal neurogenesis by the triplication of the Erg gene in mouse models of Down syndrome.
Keiichi Ishihara, Ryohei Shimizu, Kazuyuki Takata, Eri Kawashita, Kenji Amano, Satoshi Akiba

Brain Pathol· January 2020

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[Copper accumulation in the brain of Down syndrome model mice and its pathophysiological significance].
Keiichi Ishihara, Eri Kawashita, Satoshi Akiba

Nihon Yakurigaku Zasshi· December 2019

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Copper accumulation in the brain causes the elevation of oxidative stress and less anxious behavior in Ts1Cje mice, a model of Down syndrome.
Keiichi Ishihara, Eri Kawashita, Ryohei Shimizu, Kazuki Nagasawa, Hiroyuki Yasui, Satoshi Akiba

Free Radic Biol Med· April 2019

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A comparative analysis of hepatic pathological phenotypes in C57BL/6J and C57BL/6N mouse strains in non-alcoholic steatohepatitis models.
Eri Kawashita, Keiichi Ishihara, Madoka Nomoto, Mika Taniguchi, Satoshi Akiba

Sci Rep· January 2019

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Antigen-specific airway IL-33 production depends on FcγR-mediated incorporation of the antigen by alveolar macrophages in sensitized mice.
Takeshi Nabe, Masaya Matsuda, Tomoki Ishida, Nau Tsujimoto, Hitomi Kido, Satoshi Akiba

Immunology· September 2018

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Ts1Cje Down syndrome model mice exhibit environmental stimuli-triggered locomotor hyperactivity and sociability concurrent with increased flux through central dopamine and serotonin metabolism.
Atsushi Shimohata, Keiichi Ishihara, Satoko Hattori, Hiroyuki Miyamoto, Hiromasa Morishita, Satoshi Akiba

Exp Neurol· July 2017

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A Comprehensive Diverse '-omics' Approach to Better Understanding the Molecular Pathomechanisms of Down Syndrome.
Keiichi Ishihara, Satoshi Akiba

Brain Sci· April 2017

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ASB14780, an Orally Active Inhibitor of Group IVA Phospholipase A2, Is a Pharmacotherapeutic Candidate for Nonalcoholic Fatty Liver Disease.
Shiho Kanai, Keiichi Ishihara, Eri Kawashita, Toshiyuki Tomoo, Kazuhiro Nagahira, Satoshi Akiba

J Pharmacol Exp Ther· March 2016

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Group IVA phospholipase A(2) deficiency prevents CCl4-induced hepatic cell death through the enhancement of autophagy.
Keiichi Ishihara, Shiho Kanai, Kikuko Tanaka, Eri Kawashita, Satoshi Akiba

Biochem Biophys Res Commun· February 2016

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Production of interleukin (IL)-33 in the lungs during multiple antigen challenge-induced airway inflammation in mice, and its modulation by a glucocorticoid.
Takeshi Nabe, Hiroki Wakamori, Chihiro Yano, Ayumi Nishiguchi, Rino Yuasa, Satoshi Akiba

Eur J Pharmacol· June 2015

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Piperine inhibits the activities of platelet cytosolic phospholipase A2 and thromboxane A2 synthase without affecting cyclooxygenase-1 activity: different mechanisms of action are involved in the inhibition of platelet aggregation and macrophage inflammatory response.
Dong Ju Son, Satoshi Akiba, Jin Tae Hong, Yeo Pyo Yun, Seock Yeon Hwang

Nutrients· August 2014

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Effect of a peroxynitrite scavenger, a manganese-porphyrin compound on airway remodeling in a murine asthma.
Yang Cao, Masanori Fujii, Keiichi Ishihara, Satoshi Akiba, Hiroyuki Yasui

Biol Pharm Bull· January 2014

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Group IVA phospholipase A2 participates in the progression of hepatic fibrosis.
Keiichi Ishihara, Akira Miyazaki, Takeshi Nabe, Hideaki Fushimi, Nao Iriyama, Satoshi Akiba

FASEB J· October 2012

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Regulatory role of antigen-induced interleukin-10, produced by CD4(+) T cells, in airway neutrophilia in a murine model for asthma.
Takeshi Nabe, Ayumu Ikedo, Fusa Hosokawa, Maki Kishima, Masanori Fujii, Satoshi Akiba

Eur J Pharmacol· February 2012

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