Publications by authors named "Saud A Sadiq"

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Central TYK2 inhibition identifies TYK2 as a key neuroimmune modulator.
Tyler P Molitor, Genki Hayashi, Mei-Yao Lin, Carissa J Dunn, Nathan G Peterson, Saud A Sadiq

Proc Natl Acad Sci U S A· April 2025

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Efficacy of intrathecal mesenchymal stem cell-neural progenitor therapy in progressive MS: results from a phase II, randomized, placebo-controlled clinical trial.
Violaine K Harris, James Stark, Armistead Williams, Morgan Roche, Michaela Malin, Saud A Sadiq

Stem Cell Res Ther· May 2024

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Mesenchymal stem cell-neural progenitors are enriched in cell signaling molecules implicated in their therapeutic effect in multiple sclerosis.
Violaine K Harris, Jaina Wollowitz, Jacelyn Greenwald, Alyssa L Carlson, Saud A Sadiq

PLoS One· August 2023

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Humoral and cellular responses to repeated COVID-19 exposure in multiple sclerosis patients receiving B-cell depleting therapies: a single-center, one-year, prospective study.
Roberto Alfonso-Dunn, Jerry Lin, Joyce Lei, Jiayuan Liu, Morgan Roche, Saud A Sadiq

Front Immunol· July 2023

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Cerebrospinal fluid immunoglobulins in primary progressive multiple sclerosis are pathogenic.
Jamie K Wong, Jerry Lin, Nathan J Kung, Alexandra L Tse, Serena J E Shimshak, Saud A Sadiq

Brain· May 2023

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Cerebral organoids in primary progressive multiple sclerosis reveal stem cell and oligodendrocyte differentiation defect.
Nicolas Daviaud, Eric Chen, Tara Edwards, Saud A Sadiq

Biol Open· March 2023

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Mesenchymal stem cell-derived neural progenitors attenuate proinflammatory microglial activation via paracrine mechanisms.
Violaine K Harris, Derek Bishop, Jaina Wollowitz, Gillian Carling, Alyssa L Carlson, Saud A Sadiq

Regen Med· March 2023

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Strong T-cell activation in response to COVID-19 vaccination in multiple sclerosis patients receiving B-cell depleting therapies.
Roberto Alfonso-Dunn, Jerry Lin, Vanessa Kirschner, Joyce Lei, Grant Feuer, Saud A Sadiq

Front Immunol· August 2022

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Apolipoprotein B-100-mediated motor neuron degeneration in sporadic amyotrophic lateral sclerosis.
Jamie K Wong, Anna K Roselle, Taylor M Shue, Serena J E Shimshak, Joseph M Beaty, Saud A Sadiq

Brain Commun· August 2022

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Mesenchymal stem cell-derived neural progenitors in progressive MS: Two-year follow-up of a phase I study.
Violaine K Harris, James W Stark, Sophia Yang, Shayna Zanker, John Tuddenham, Saud A Sadiq

Neurol Neuroimmunol Neuroinflamm· January 2021

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Stem cells in amyotrophic lateral sclerosis: Hype or hope?
Saud A Sadiq, Christen Shoesmith

Neurology· December 2019

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Safety of long-term intrathecal methotrexate in progressive forms of MS.
James W Stark, Lena Josephs, Deirdre Dulak, Madison Clague, Saud A Sadiq

Ther Adv Neurol Disord· December 2019

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Adenosine A2A receptor agonist ameliorates EAE and correlates with Th1 cytokine-induced blood brain barrier dysfunction via suppression of MLCK signaling pathway.
Ying Liu, Marwan Alahiri, Bianca Ulloa, Boxun Xie, Saud A Sadiq

Immun Inflamm Dis· March 2018

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Phase I Trial of Intrathecal Mesenchymal Stem Cell-derived Neural Progenitors in Progressive Multiple Sclerosis.
Violaine K Harris, James Stark, Tamara Vyshkina, Leslie Blackshear, Gloria Joo, Saud A Sadiq

EBioMedicine· March 2018

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Transglutaminase-6 is an autoantigen in progressive multiple sclerosis and is upregulated in reactive astrocytes.
Massimiliano Cristofanilli, Daniel Gratch, Benjamin Pagano, Kelsey McDermott, Jessie Huang, Saud A Sadiq

Mult Scler· November 2017

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Fetuin-A deficiency protects mice from Experimental Autoimmune Encephalomyelitis (EAE) and correlates with altered innate immune response.
Violaine K Harris, Lena Bell, Ruth-Anne Langan, John Tuddenham, Mark Landy, Saud A Sadiq

PLoS One· September 2017

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Biomarkers of multiple sclerosis: current findings.
Violaine K Harris, John F Tuddenham, Saud A Sadiq

Degener Neurol Neuromuscul Dis· January 2017

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Clinical safety of intrathecal administration of mesenchymal stromal cell-derived neural progenitors in multiple sclerosis.
Violaine K Harris, Tamara Vyshkina, Saud A Sadiq

Cytotherapy· December 2016

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Stem cell therapy in multiple sclerosis: a future perspective.
Violaine K Harris, Saud A Sadiq

Neurodegener Dis Manag· March 2016

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Biomarkers of therapeutic response in multiple sclerosis: current status.
Violaine K Harris, Saud A Sadiq

Mol Diagn Ther· December 2014

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Progressive multiple sclerosis cerebrospinal fluid induces inflammatory demyelination, axonal loss, and astrogliosis in mice.
Massimiliano Cristofanilli, Hannah Rosenthal, Barbara Cymring, Daniel Gratch, Benjamin Pagano, Saud A Sadiq

Exp Neurol· November 2014

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Inhibition of hyaluronan synthesis protects against central nervous system (CNS) autoimmunity and increases CXCL12 expression in the inflamed CNS.
Andre Michael Mueller, Bo Hyung Yoon, Saud Ahmed Sadiq

J Biol Chem· August 2014

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CSF isoprostane levels are a biomarker of oxidative stress in multiple sclerosis.
Fozia Mir, Donald Lee, Hetal Ray, Saud A Sadiq

Neurol Neuroimmunol Neuroinflamm· August 2014

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Effects of intraventricular methotrexate administration on Cuprizone-induced demyelination in mice.
Andre M Mueller, Adam Nassery, Hana Conlon, Xinhe Liu, Esther Jun, Saud A Sadiq

Front Mol Neurosci· October 2013

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Cerebrospinal fluid and serum JC virus antibody detection in multiple sclerosis patients treated with natalizumab.
Jerry Lin, Peggy Bettin, John K Lee, Joseph K Ho, Saud A Sadiq

J Neuroimmunol· August 2013

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