Publications by authors named "Scott A Long"

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Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist.
Mark E Schnute, Mattias Wennerstål, Jennifer Alley, Martin Bengtsson, James R Blinn, Scott A Long

J Med Chem· December 2018

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Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 2. Discovery of 7-azaspiro[3.5]nonane urea PF-04862853, an orally efficacious inhibitor of fatty acid amide hydrolase (FAAH) for pain.
Marvin J Meyers, Scott A Long, Matthew J Pelc, Jane L Wang, Scott J Bowen

Bioorg Med Chem Lett· November 2011

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Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 1: identification of 7-azaspiro[3.5]nonane and 1-oxa-8-azaspiro[4.5]decane as lead scaffolds.
Marvin J Meyers, Scott A Long, Matthew J Pelc, Jane L Wang, Scott J Bowen

Bioorg Med Chem Lett· November 2011

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Discovery of (3S,3aR)-2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic acid (PF-3882845), an orally efficacious mineralocorticoid receptor (MR) antagonist for hypertension and nephropathy.
Marvin J Meyers, Graciela B Arhancet, Susan L Hockerman, Xiangyang Chen, Scott A Long

J Med Chem· August 2010

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Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode.
Marvin J Meyers, Matthew Pelc, Satwik Kamtekar, Jacqueline Day, Gennadiy I Poda, Scott A Long

Bioorg Med Chem Lett· March 2010

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Benzothiophene inhibitors of MK2. Part 2: improvements in kinase selectivity and cell potency.
David R Anderson, Marvin J Meyers, Ravi G Kurumbail, Nicole Caspers, Gennadiy I Poda, Scott A Long

Bioorg Med Chem Lett· August 2009

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Benzothiophene inhibitors of MK2. Part 1: structure-activity relationships, assessments of selectivity and cellular potency.
David R Anderson, Marvin J Meyers, Ravi G Kurumbail, Nicole Caspers, Gennadiy I Poda, Scott A Long

Bioorg Med Chem Lett· August 2009

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