Publications by authors named "Scott Gleim"

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Author Correction: DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance.
Martin Schröder, Martin Renatus, Xiaoyou Liang, Fabian Meili, Thomas Zoller, Scott Gleim

Nat Commun· August 2024

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DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance.
Martin Schröder, Martin Renatus, Xiaoyou Liang, Fabian Meili, Thomas Zoller, Scott Gleim

Nat Commun· January 2024

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Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase.
Klemens Hoegenauer, Shaojian An, Jake Axford, Christina Benander, Christian Bergsdorf, Scott Gleim

ACS Med Chem Lett· December 2023

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BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma.
Ellen Weisberg, Basudev Chowdhury, Chengcheng Meng, Abigail E Case, Wei Ni, Scott Gleim

Blood Cancer J· July 2022

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A strategy to assess the cellular activity of E3 ligase components against neo-substrates using electrophilic probes.
Benika J Pinch, Dennis L Buckley, Scott Gleim, Scott M Brittain, Laura Tandeske

Cell Chem Biol· January 2022

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CYP27A1-dependent anti-melanoma activity of limonoid natural products targets mitochondrial metabolism.
Hyelim Cho, Qiong Shen, Lydia H Zhang, Mikiko Okumura, Akinori Kawakami, Scott Gleim

Cell Chem Biol· October 2021

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Identification of the HECT E3 ligase UBR5 as a regulator of MYC degradation using a CRISPR/Cas9 screen.
Lina Schukur, Tamara Zimmermann, Ole Niewoehner, Grainne Kerr, Scott Gleim

Sci Rep· November 2020

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Author Correction: CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma.
Nathan T Ross, Felix Lohmann, Seth Carbonneau, Aleem Fazal, Wilhelm A Weihofen, Scott Gleim

Nat Chem Biol· April 2020

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CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma.
Nathan T Ross, Felix Lohmann, Seth Carbonneau, Aleem Fazal, Wilhelm A Weihofen, Scott Gleim

Nat Chem Biol· January 2020

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Benchmarking network algorithms for contextualizing genes of interest.
Abby Hill, Scott Gleim, Florian Kiefer, Frederic Sigoillot, Joseph Loureiro

PLoS Comput Biol· December 2019

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Application of Large-Scale Aptamer-Based Proteomic Profiling to Planned Myocardial Infarctions.
Jaison Jacob, Debby Ngo, Nancy Finkel, Rebecca Pitts, Scott Gleim

Circulation· March 2018

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Recurrent ubiquitin B silencing in gynecological cancers establishes dependence on ubiquitin C.
Alexia T Kedves, Scott Gleim, Xiaoyou Liang, Dennis M Bonal, Frederic Sigoillot

J Clin Invest· December 2017

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Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibition.
Yi Xie, Yu Jin, Bethany L Merenick, Min Ding, Kristina M Fetalvero, Scott Gleim

Sci Signal· May 2015

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Aldose reductase-mediated phosphorylation of p53 leads to mitochondrial dysfunction and damage in diabetic platelets.
Wai Ho Tang, Jeremiah Stitham, Yu Jin, Renjing Liu, Seung Hee Lee, Scott Gleim

Circulation· April 2014

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Human thromboxane A2 receptor genetic variants: in silico, in vitro and "in platelet" analysis.
Scott Gleim, Jeremiah Stitham, Wai Ho Tang, Hong Li, Karen Douville

PLoS One· January 2014

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Biased suppression of TP homodimerization and signaling through disruption of a TM GxxxGxxxL helical interaction motif.
Alexander J Frey, Salam Ibrahim, Scott Gleim, John Hwa, Emer M Smyth

J Lipid Res· June 2013

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Apelin-APJ signaling is a critical regulator of endothelial MEF2 activation in cardiovascular development.
Yujung Kang, Jongmin Kim, Joshua P Anderson, Jingxia Wu, Scott R Gleim

Circ Res· June 2013

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New insights into structural determinants for prostanoid thromboxane A2 receptor- and prostacyclin receptor-G protein coupling.
Raja Chakraborty, Sai Prasad Pydi, Scott Gleim, Rajinder Pal Bhullar, John Hwa

Mol Cell Biol· January 2013

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An eicosanoid-centric view of atherothrombotic risk factors.
Scott Gleim, Jeremiah Stitham, Wai Ho Tang, Kathleen A Martin, John Hwa

Cell Mol Life Sci· October 2012

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Hospital patterns of use of positive inotropic agents in patients with heart failure.
Chohreh Partovian, Scott R Gleim, Purav S Mody, Shu-Xia Li, Haiyan Wang

J Am Coll Cardiol· October 2012

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Site-directed mutations and the polymorphic variant Ala160Thr in the human thromboxane receptor uncover a structural role for transmembrane helix 4.
Raja Chakraborty, Sai Prasad Pydi, Scott Gleim, Shyamala Dakshinamurti, John Hwa

PLoS One· June 2012

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Glucose and collagen regulate human platelet activity through aldose reductase induction of thromboxane.
Wai Ho Tang, Jeremiah Stitham, Scott Gleim, Concetta Di Febbo, Ettore Porreca

J Clin Invest· November 2011

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Comprehensive biochemical analysis of rare prostacyclin receptor variants: study of association of signaling with coronary artery obstruction.
Jeremiah Stitham, Eric Arehart, Larkin Elderon, Scott R Gleim, Karen Douville

J Biol Chem· March 2011

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Prostacyclin receptor/thromboxane receptor interactions and cellular responses in human atherothrombotic disease.
Scott Gleim, Zsolt Kasza, Kathleen Martin, John Hwa

Curr Atheroscler Rep· May 2009

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Multifactor dimensionality reduction analysis identifies specific nucleotide patterns promoting genetic polymorphisms.
Eric Arehart, Scott Gleim, Bill White, John Hwa, Jason H Moore

BioData Min· March 2009

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