Publications by authors named "Scott Hultgren"

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The Unique Efg1 Fungal Virulence Regulon in the Catheterized Bladder Environment.
Alyssa Ann La Bella, Nicholas C Gervais, Kurt N Kohler, Chloe L P Obernuefemann, Ilse D Jacobsen, Scott J Hultgren

bioRxiv· November 2025

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De Novo Design of Miniprotein Inhibitors of Bacterial Adhesins.
Adam Chazin-Gray, Tuscan Thompson, Edward Lopatto, Pearl Magala, Patrick Erickson, Scott Hultgren

Res Sq· November 2025

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Metabolic cross-talk promotes persistence of in a model of polymicrobial catheter-associated urinary tract infection.
Zongsen Zou, Jerome S Pinkner, Chloe L P Obernuefemann, Kent R Kleinschmidt, Denise A Sanick, Scott J Hultgren

bioRxiv· November 2025

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Uropathogenic Escherichia coli niche occupancy determines the effects of mucosal vaccine against FimH.
Jesús M Santiago-Borges, Anne L Rosen, Ariel Hernandez-Leyva, Christopher P Tomera, Michael A Lint, Scott J Hultgren

Cell Rep· August 2025

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Vaccination with Acinetobacter baumannii adhesin Abp2D provides protection against catheter-associated urinary tract infection.
Morgan R Timm, Kevin O Tamadonfar, Taylor M Nye, Jesús Bazán Villicaña, Jerome S Pinkner, Scott J Hultgren

Nat Commun· August 2025

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Design of Miniprotein Inhibitors of Bacterial Adhesins.
Adam M Chazin-Gray, Tuscan R Thompson, Edward D B Lopatto, Pearl Magala, Patrick W Erickson, Scott J Hultgren

bioRxiv· August 2025

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Author Correction: Longitudinal profiling of low-abundance strains in microbiomes with ChronoStrain.
Younhun Kim, Colin J Worby, Sawal Acharya, Lucas R van Dijk, Daniel Alfonsetti, Scott J Hultgren

Nat Microbiol· June 2025

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Monoclonal antibodies targeting the FimH adhesin protect against uropathogenic UTI.
Edward D B Lopatto, Jesús M Santiago-Borges, Denise A Sanick, Sameer Kumar Malladi, Philippe N Azimzadeh, Scott J Hultgren

Sci Adv· June 2025

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Longitudinal profiling of low-abundance strains in microbiomes with ChronoStrain.
Younhun Kim, Colin J Worby, Sawal Acharya, Lucas R van Dijk, Daniel Alfonsetti, Scott J Hultgren

Nat Microbiol· May 2025

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Urinary tract infections: pathogenesis, host susceptibility and emerging therapeutics.
Morgan R Timm, Seongmi K Russell, Scott J Hultgren

Nat Rev Microbiol· February 2025

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Mechanisms of uropathogenic mucosal association in the gastrointestinal tract.
Philippe N Azimzadeh, George M Birchenough, Nathaniel C Gualbuerto, Jerome S Pinkner, Kevin O Tamadonfar, Scott J Hultgren

Sci Adv· January 2025

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Monoclonal antibodies targeting the FimH adhesin protect against uropathogenic UTI.
Edward D B Lopatto, Jesús M Santiago-Borges, Denise A Sanick, Sameer Kumar Malladi, Philippe N Azimzadeh, Scott J Hultgren

bioRxiv· December 2024

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Distinct Escherichia coli transcriptional profiles in the guts of recurrent UTI sufferers revealed by pangenome hybrid selection.
Mark G Young, Timothy J Straub, Colin J Worby, Hayden C Metsky, Andreas Gnirke, Scott J Hultgren

Nat Commun· November 2024

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Structural basis for adhesin secretion by the outer-membrane usher in type 1 pili.
Ryan M Bitter, Maxwell I Zimmerman, Brock T Summers, Jerome S Pinkner, Karen W Dodson, Scott J Hultgren

Proc Natl Acad Sci U S A· October 2024

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Conformational ensembles in FimH impact uropathogenesis.
Edward D B Lopatto, Jerome S Pinkner, Denise A Sanick, Robert F Potter, Lily X Liu, Scott J Hultgren

Proc Natl Acad Sci U S A· September 2024

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Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat skin and soft tissue infection.
Zongsen Zou, Pardeep Singh, Jerome S Pinkner, Chloe L P Obernuefemann, Wei Xu, Scott J Hultgren

Sci Adv· August 2024

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Distinct transcriptional profiles in the guts of recurrent UTI sufferers revealed by pangenome hybrid selection.
Mark G Young, Timothy J Straub, Colin J Worby, Hayden C Metsky, Andreas Gnirke, Scott J Hultgren

bioRxiv· June 2024

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Discovery of Orally Bioavailable FmlH Lectin Antagonists as Treatment for Urinary Tract Infections.
Amarendar Reddy Maddirala, Kevin Tamadonfar, Jerome S Pinkner, Denise Sanick, Scott J Hultgren

J Med Chem· March 2024

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Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI.
Jonathan J Molina, Kurt N Kohler, Christopher Gager, Marissa J Andersen, Ellsa Wongso, Scott J Hultgren

Nat Commun· March 2024

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Case report: Long-term follow-up of patients who received a FimCH vaccine for prevention of recurrent urinary tract infections caused by antibiotic resistant Enterobacteriaceae: a case report series.
Elise Perer, Helen Stacey, Terri Eichorn, Heidi Hughey, Julie Lawrence, Scott J Hultgren

Front Immunol· March 2024

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Secretory leukocyte protease inhibitor protects against severe urinary tract infection in mice.
Anne L Rosen, Michael A Lint, Dayne H Voelker, Nicole M Gilbert, Christopher P Tomera, Scott J Hultgren

mBio· February 2024

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Microbial co-occurrences on catheters from long-term catheterized patients.
Taylor M Nye, Zongsen Zou, Chloe L P Obernuefemann, Jerome S Pinkner, Erin Lowry, Scott J Hultgren

Nat Commun· January 2024

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Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat skin and soft tissue infection.
Zongsen Zou, Chloe L P Obernuefemann, Pardeep Singh, Jerome S Pinkner, Wei Xu, Scott J Hultgren

bioRxiv· January 2024

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Secretory Leukocyte Protease Inhibitor Protects Against Severe Urinary Tract Infection in Mice.
Anne L Rosen, Michael A Lint, Dayne H Voelker, Nicole M Gilbert, Christopher P Tomera, Scott J Hultgren

bioRxiv· October 2023

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Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI.
Jonathan J Molina, Kurt N Kohler, Christopher Gager, Marissa J Andersen, Ellsa Wongso, Scott J Hultgren

Res Sq· September 2023

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