Publications by authors named "Scott Loughhead"

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Final outcomes analysis of the cell product SQZ-PBMC-HPV Phase 1 trial in incurable HPV16+ solid tumors shows improved overall survival in patients with increased CD8+ T cell tumor infiltration.
Alice N Weaver, Wade T Iams, Jong Chul Park, Monica Mita, Udo Holtick, Scott Loughhead

Mol Carcinog· August 2024

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Phase 1 study to determine the safety and dosing of autologous PBMCs modified to present HPV16 antigens (SQZ-PBMC-HPV) in HLA-A*02+ patients with HPV16+ solid tumors.
Antonio Jimeno, Joaquina Baranda, Wade T Iams, Jong Chul Park, Monica Mita, Scott M Loughhead

Invest New Drugs· April 2023

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Engineered red blood cells (activating antigen carriers) drive potent T cell responses and tumor regression in mice.
Katarina Blagovic, Carolyne K Smith, Amritha Ramakrishnan, Lindsay Moore, David R Soto, Scott Loughhead

Front Immunol· October 2022

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Microfluidic Squeezing Enables MHC Class I Antigen Presentation by Diverse Immune Cells to Elicit CD8 T Cell Responses with Antitumor Activity.
Matthew G Booty, Kelan A Hlavaty, Adam Stockmann, Emrah Ilker Ozay, Carolyne Smith, Scott M Loughhead

J Immunol· February 2022

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Cell engineering with microfluidic squeezing preserves functionality of primary immune cells in vivo.
Tia DiTommaso, Julie M Cole, Luke Cassereau, Joshua A Buggé, Jacquelyn L Sikora Hanson, Scott M Loughhead

Proc Natl Acad Sci U S A· November 2018

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Spinal cord injury-induced immunodeficiency is mediated by a sympathetic-neuroendocrine adrenal reflex.
Harald Prüss, Andrea Tedeschi, Aude Thiriot, Lydia Lynch, Scott M Loughhead

Nat Neurosci· November 2017

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, a long noncoding RNA, modulates Foxp3 expression and autoimmunity.
David Zemmour, Alvin Pratama, Scott M Loughhead, Diane Mathis, Christophe Benoist

Proc Natl Acad Sci U S A· April 2017

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The Chemokine Receptor CX3CR1 Defines Three Antigen-Experienced CD8 T Cell Subsets with Distinct Roles in Immune Surveillance and Homeostasis.
Carmen Gerlach, E Ashley Moseman, Scott M Loughhead, David Alvarez, Anthonie J Zwijnenburg

Immunity· December 2016

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Targeted Delivery of Immunomodulators to Lymph Nodes.
Jamil Azzi, Qian Yin, Mayuko Uehara, Shunsuke Ohori, Li Tang, Scott Loughhead

Cell Rep· May 2016

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Figuring fact from fiction: unbiased polling of memory T cells.
Carmen Gerlach, Scott M Loughhead, Ulrich H von Andrian

Cell· May 2015

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Antigen availability determines CD8⁺ T cell-dendritic cell interaction kinetics and memory fate decisions.
Sarah E Henrickson, Mario Perro, Scott M Loughhead, Balimkiz Senman, Susanne Stutte

Immunity· September 2013

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Polyfunctional CD4+ T cell responses to immunodominant epitopes correlate with disease activity of virulent Salmonella.
Matt Maybeno, Anke Redeker, Suzanne P M Welten, Bjoern Peters, Scott M Loughhead

PLoS One· March 2013

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Constitutively active ezrin increases membrane tension, slows migration, and impedes endothelial transmigration of lymphocytes in vivo in mice.
Yin Liu, Natalya V Belkina, Chung Park, Raj Nambiar, Scott M Loughhead

Blood· January 2012

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