Publications by authors named "Scott McConnell"

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New insights into antibody structure with implications for specificity, variable region restriction and isotype choice.
Scott A McConnell, Arturo Casadevall

Nat Rev Immunol· August 2025

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A Cryptococcus neoformans polysaccharide conjugate vaccine made with filtered polysaccharide elicits protective immunity in mice.
Piotr R Stempinski, Paola Ramos Irizarry, Scott A McConnell, Livia C Liporagi Lopes, Samuel Rodrigues Dos Santos Júnior

Fungal Biol· April 2025

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Considerations for the development of monoclonal antibodies to address new viral variants in COVID-19.
Arturo Casadevall, Scott McConnell, Daniele Focosi

Expert Opin Biol Ther· August 2024

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Immunoglobulin constant regions provide stabilization to the paratope and enforce epitope specificity.
Scott A McConnell, Arturo Casadevall

J Biol Chem· June 2024

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Methods of Cryptococcal Polysaccharide Analysis Using ELISA.
Maggie P Wear, Scott A McConnell, Seth D Greengo, Livia Liporagi Lopes, Arturo Casadevall

Methods Mol Biol· May 2024

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Synthetic Glycans Reveal Determinants of Antibody Functional Efficacy against a Fungal Pathogen.
Conor J Crawford, Lorenzo Guazzelli, Scott A McConnell, Orla McCabe, Clotilde d'Errico

ACS Infect Dis· February 2024

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The basal and major pilins in the Corynebacterium diphtheriae SpaA pilus adopt similar structures that competitively react with the pilin polymerase.
Christopher K Sue, Nicole A Cheung, Brendan J Mahoney, Scott A McConnell, Jack M Scully

Biopolymers· January 2024

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Analysis of SARS-CoV-2 mutations associated with resistance to therapeutic monoclonal antibodies that emerge after treatment.
Daniele Focosi, Scott McConnell, David J Sullivan, Arturo Casadevall

Drug Resist Updat· November 2023

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Spike-protein proteolytic antibodies in COVID-19 convalescent plasma contribute to SARS-CoV-2 neutralization.
Scott A McConnell, Jaiprasath Sachithanandham, Nathan J Mudrak, Xianming Zhu, Parsa Alba Farhang

Cell Chem Biol· July 2023

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Rise of the BQ.1.1.37 SARS-CoV-2 Sublineage, Italy.
Daniele Focosi, Pietro Giorgio Spezia, Anna-Lisa Capria, Federico Gueli, Scott McConnell

Diagnostics (Basel)· March 2023

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Nirmatrelvir and COVID-19: development, pharmacokinetics, clinical efficacy, resistance, relapse, and pharmacoeconomics.
Daniele Focosi, Scott McConnell, Shmuel Shoham, Arturo Casadevall, Fabrizio Maggi

Int J Antimicrob Agents· February 2023

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The Basal and Major Pilins in the SpaA Pilus Adopt Similar Structures that Competitively React with the Pilin Polymerase.
Christopher K Sue, Nicole A Cheung, Brendan J Mahoney, Scott A McConnell, Jack M Scully

bioRxiv· February 2023

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Similar evolutionary trajectories in an environmental isolate after human and murine infection.
Poppy Sephton-Clark, Scott A McConnell, Nina Grossman, Rosanna P Baker, Quigly Dragotakes

Proc Natl Acad Sci U S A· January 2023

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Convergent Evolution in SARS-CoV-2 Spike Creates a Variant Soup from Which New COVID-19 Waves Emerge.
Daniele Focosi, Rodrigo Quiroga, Scott McConnell, Marc C Johnson, Arturo Casadevall

Int J Mol Sci· January 2023

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The Omicron variant of concern: Diversification and convergent evolution in spike protein, and escape from anti-Spike monoclonal antibodies.
Daniele Focosi, Scott McConnell, Arturo Casadevall

Drug Resist Updat· December 2022

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Monoclonal antibody therapies against SARS-CoV-2.
Daniele Focosi, Scott McConnell, Arturo Casadevall, Emiliano Cappello, Giulia Valdiserra

Lancet Infect Dis· November 2022

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Lyophilization induces physicochemical alterations in cryptococcal exopolysaccharide.
Maggie P Wear, Audra A Hargett, John E Kelly, Scott A McConnell, Conor J Crawford

Carbohydr Polym· September 2022

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Cryptococcus neoformans capsule regrowth experiments reveal dynamics of enlargement and architecture.
Maggie P Wear, Ella Jacobs, Siqing Wang, Scott A McConnell, Anthony Bowen

J Biol Chem· April 2022

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Spike mutations in SARS-CoV-2 AY sublineages of the Delta variant of concern: implications for the future of the pandemic.
Daniele Focosi, Fabrizio Maggi, Scott McConnell, Arturo Casadevall

Future Microbiol· March 2022

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Very low levels of remdesivir resistance in SARS-COV-2 genomes after 18 months of massive usage during the COVID19 pandemic: A GISAID exploratory analysis.
Daniele Focosi, Fabrizio Maggi, Scott McConnell, Arturo Casadevall

Antiviral Res· February 2022

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Analysis of Immune Escape Variants from Antibody-Based Therapeutics against COVID-19: A Systematic Review.
Daniele Focosi, Fabrizio Maggi, Massimo Franchini, Scott McConnell, Arturo Casadevall

Int J Mol Sci· December 2021

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Parent education to improve early language development: A preliminary evaluation of LENA Start.
Marianne Elmquist, Lizbeth H Finestack, Amanda Kriese, Erin M Lease, Scott R McConnell

J Child Lang· July 2021

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Sortase-assembled pili in are built using a latch mechanism.
Scott A McConnell, Rachel A McAllister, Brendan R Amer, Brendan J Mahoney, Christopher K Sue

Proc Natl Acad Sci U S A· March 2021

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A glycan FRET assay for detection and characterization of catalytic antibodies to the capsule.
Conor J Crawford, Maggie P Wear, Daniel F Q Smith, Clotilde d'Errico, Scott A McConnell

Proc Natl Acad Sci U S A· February 2021

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Kinetics and Optimization of the Lysine-Isopeptide Bond Forming Sortase Enzyme from .
Christopher K Sue, Scott A McConnell, Ken Ellis-Guardiola, John M Muroski, Rachel A McAllister

Bioconjug Chem· June 2020

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