Publications by authors named "Scott Nolan"

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Deep top-down proteomics revealed significant proteoform-level differences between metastatic and nonmetastatic colorectal cancer cells.
Elijah N McCool, Tian Xu, Wenrong Chen, Nicole C Beller, Scott M Nolan

Sci Adv· December 2022

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Discovery of the Oxadiazine FRM-024: A Potent CNS-Penetrant Gamma Secretase Modulator.
Matthew G Bursavich, Bryce A Harrison, Raksha Acharya, Donald E Costa, Emily A Freeman, Scott J Nolan

J Med Chem· October 2021

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Design, Synthesis, and Evaluation of a Novel Series of Oxadiazine Gamma Secretase Modulators for Familial Alzheimer's Disease.
Matthew G Bursavich, Bryce A Harrison, Raksha Acharya, Donald E Costa, Emily A Freeman, Scott Nolan

J Med Chem· March 2017

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Characterization of FRM-36143 as a new γ-secretase modulator for the potential treatment of familial Alzheimer's disease.
Jean-François Blain, Matthew G Bursavich, Emily A Freeman, Lori A Hrdlicka, Hilliary E Hodgdon, Scott Nolan

Alzheimers Res Ther· August 2016

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Immunogenicity without Efficacy of an Adenoviral Tuberculosis Vaccine in a Stringent Mouse Model for Immunotherapy during Treatment.
S Anisah Alyahya, Scott T Nolan, Cara M R Smith, William R Bishai, Jerald Sadoff

PLoS One· March 2016

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In the hot zone. Public health veterinarians help rein in West African Ebola outbreak.
R Scott Nolan

J Am Vet Med Assoc· May 2015

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AVMA issues guidance on humane slaughter.
R Scott Nolan

J Am Vet Med Assoc· February 2015

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Neuropharmacokinetics of two investigational compounds in rats: divergent temporal profiles in the brain and cerebrospinal fluid.
Cuyue Tang, Ting Chen, Sudarshan Kapadnis, Hilliary Hodgdon, Yi Tao, Scott Nolan

Biochem Pharmacol· October 2014

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A practitioner, through and through AVMA President Fobian reflects on his time in office.
Clark K Fobian, R Scott Nolan

J Am Vet Med Assoc· May 2014

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Modulation of γ-secretase by EVP-0015962 reduces amyloid deposition and behavioral deficits in Tg2576 mice.
Kathryn Rogers, Kevin M Felsenstein, Lori Hrdlicka, Zhiming Tu, Faris Albayya, Scott Nolan

Mol Neurodegener· December 2012

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Isoniazid resistance without a loss of fitness in Mycobacterium tuberculosis.
Jong-Hee Lee, Nicole C Ammerman, Scott Nolan, Deborah E Geiman, Shichun Lun

Nat Commun· March 2012

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Essential metabolites of Mycobacterium tuberculosis and their mimics.
Gyanu Lamichhane, Joel S Freundlich, Sean Ekins, Niluka Wickramaratne, Scott T Nolan

mBio· February 2011

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Copper resistance is essential for virulence of Mycobacterium tuberculosis.
Frank Wolschendorf, David Ackart, Tej B Shrestha, Laurel Hascall-Dove, Scott Nolan

Proc Natl Acad Sci U S A· January 2011

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Protective efficacy of BCG overexpressing an L,D-transpeptidase against M. tuberculosis infection.
Scott T Nolan, Gyanu Lamichhane

PLoS One· October 2010

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The impact of mouse passaging of Mycobacterium tuberculosis strains prior to virulence testing in the mouse and guinea pig aerosol models.
Paul J Converse, Kathleen D Eisenach, Sue A Theus, Eric L Nuermberger, Sandeep Tyagi, Scott T Nolan

PLoS One· April 2010

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Say what? What we communicate about animals says a lot about ourselves.
R Scott Nolan

J Am Vet Med Assoc· January 2010

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Cyclic AMP intoxication of macrophages by a Mycobacterium tuberculosis adenylate cyclase.
Nisheeth Agarwal, Gyanu Lamichhane, Radhika Gupta, Scott Nolan, William R Bishai

Nature· July 2009

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Legislation addresses critical shortage of veterinarians in public health.
R Scott Nolan

J Am Vet Med Assoc· April 2007

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FUS1 regulates the opening and expansion of fusion pores between mating yeast.
Scott Nolan, Ann E Cowan, Dennis E Koppel, Hui Jin, Eric Grote

Mol Biol Cell· May 2006

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4-(2-Pyridyl)piperazine-1-benzimidazoles as potent TRPV1 antagonists.
Bin Shao, Jincheng Huang, Qun Sun, Kenneth J Valenzano, Lori Schmid, Scott Nolan

Bioorg Med Chem Lett· February 2005

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Prm1 prevents contact-dependent lysis of yeast mating pairs.
Hui Jin, Candice Carlile, Scott Nolan, Eric Grote

Eukaryot Cell· December 2004

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A-317491, a selective P2X3/P2X2/3 receptor antagonist, reverses inflammatory mechanical hyperalgesia through action at peripheral receptors in rats.
Gang Wu, Garth T Whiteside, Gary Lee, Scott Nolan, Mark Niosi

Eur J Pharmacol· November 2004

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DiPOA ([8-(3,3-diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl]-acetic acid), a novel, systemically available, and peripherally restricted mu opioid agonist with antihyperalgesic activity: I. In vitro pharmacological characterization and pharmacokinetic properties.
Kenneth J Valenzano, Wendy Miller, Zhengming Chen, Shen Shan, Gregg Crumley, Scott J Nolan

J Pharmacol Exp Ther· August 2004

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Investigation of a conserved stacking interaction in target site recognition by the U1A protein.
Jerome C Shiels, Jacob B Tuite, Scott J Nolan, Anne M Baranger

Nucleic Acids Res· January 2002

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