Publications by authors named "Scott R Tyler"

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Anti-correlated feature selection prevents false discovery of subpopulations in scRNAseq.
Scott R Tyler, Daniel Lozano-Ojalvo, Ernesto Guccione, Eric E Schadt

Nat Commun· January 2024

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Acetate supplementation rescues social deficits and alters transcriptional regulation in prefrontal cortex of Shank3 deficient mice.
Aya Osman, Nicholas L Mervosh, Ana N Strat, Tanner J Euston, Gillian Zipursky, Scott R Tyler

Brain Behav Immun· November 2023

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Allergen recognition by specific effector Th2 cells enables IL-2-dependent activation of regulatory T-cell responses in humans.
Daniel Lozano-Ojalvo, Scott R Tyler, Carlos J Aranda, Julie Wang, Scott Sicherer

Allergy· March 2023

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Redox-dependent Igfbp2 signaling controls Brca1 DNA damage response to govern neural stem cell fate.
Weam S Shahin, Shima O Ebed, Scott R Tyler, Branko Miljkovic, Soon H Choi

Nat Commun· January 2023

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Is the plasticity of the Th17 subset a key source of allergenic Th2 responses?
Daniel Lozano-Ojalvo, Scott R Tyler, M Cecilia Berin

Allergy· October 2021

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Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children.
Noam D Beckmann, Phillip H Comella, Esther Cheng, Lauren Lepow, Aviva G Beckmann, Scott R Tyler

Nat Commun· August 2021

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Merged Affinity Network Association Clustering: Joint multi-omic/clinical clustering to identify disease endotypes.
Scott R Tyler, Yoojin Chun, Victoria M Ribeiro, Galina Grishina, Alexander Grishin

Cell Rep· April 2021

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A Molecular network approach reveals shared cellular and molecular signatures between chronic fatigue syndrome and other fatiguing illnesses.
Phillip H Comella, Edgar Gonzalez-Kozlova, Roman Kosoy, Alexander W Charney, Irene Font Peradejordi, Scott R Tyler

medRxiv· February 2021

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Cytotoxic lymphocytes are dysregulated in multisystem inflammatory syndrome in children.
Noam D Beckmann, Phillip H Comella, Esther Cheng, Lauren Lepow, Aviva G Beckmann, Scott R Tyler

medRxiv· September 2020

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Leveraging -omics for asthma endotyping.
Scott R Tyler, Supinda Bunyavanich

J Allergy Clin Immunol· July 2019

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PyMINEr Finds Gene and Autocrine-Paracrine Networks from Human Islet scRNA-Seq.
Scott R Tyler, Pavana G Rotti, Xingshen Sun, Yaling Yi, Weiliang Xie

Cell Rep· February 2019

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Highly Efficient Transgenesis in Ferrets Using CRISPR/Cas9-Mediated Homology-Independent Insertion at the ROSA26 Locus.
Miao Yu, Xingshen Sun, Scott R Tyler, Bo Liang, Anthony M Swatek

Sci Rep· February 2019

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Infection Is Not Required for Mucoinflammatory Lung Disease in CFTR-Knockout Ferrets.
Bradley H Rosen, T Idil Apak Evans, Shashanna R Moll, Jaimie S Gray, Bo Liang, Scott R Tyler

Am J Respir Crit Care Med· May 2018

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Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium.
Thomas J Lynch, Preston J Anderson, Pavana G Rotti, Scott R Tyler, Adrianne K Crooke

Cell Stem Cell· May 2018

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Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium.
Thomas J Lynch, Preston J Anderson, Pavana G Rotti, Scott R Tyler, Adrianne K Crooke

Cell Stem Cell· May 2018

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Depletion of Airway Submucosal Glands and TP63KRT5 Basal Cells in Obliterative Bronchiolitis.
Anthony M Swatek, Thomas J Lynch, Adrianne K Crooke, Preston J Anderson, Scott R Tyler

Am J Respir Crit Care Med· April 2018

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Pancreatic and Islet Remodeling in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Knockout Ferrets.
Pavana G Rotti, Weiliang Xie, Ananta Poudel, Yaling Yi, Xingshen Sun, Scott R Tyler

Am J Pathol· April 2018

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Real-Time Monitoring of Insulin Using a Graphene Field-Effect Transistor Aptameric Nanosensor.
Zhuang Hao, Yibo Zhu, Xuejun Wang, Pavana G Rotti, Christopher DiMarco, Scott R Tyler

ACS Appl Mater Interfaces· August 2017

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Wnt Signaling Regulates Airway Epithelial Stem Cells in Adult Murine Submucosal Glands.
Thomas J Lynch, Preston J Anderson, Weiliang Xie, Adrianne K Crooke, Xiaoming Liu, Scott R Tyler

Stem Cells· November 2016

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A Transient Metabolic Recovery from Early Life Glucose Intolerance in Cystic Fibrosis Ferrets Occurs During Pancreatic Remodeling.
Yaling Yi, Xingshen Sun, Katherine Gibson-Corley, Weiliang Xie, Bo Liang, Scott R Tyler

Endocrinology· May 2016

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Glandular Proteome Identifies Antiprotease Cystatin C as a Critical Modulator of Airway Hydration and Clearance.
T Idil Apak Evans, Nam Soo Joo, Nicholas W Keiser, Ziying Yan, Scott R Tyler

Am J Respir Cell Mol Biol· April 2016

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Defective innate immunity and hyperinflammation in newborn cystic fibrosis transmembrane conductance regulator-knockout ferret lungs.
Nicholas W Keiser, Susan E Birket, Idil A Evans, Scott R Tyler, Adrianne K Crooke

Am J Respir Cell Mol Biol· June 2015

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The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease.
Xinxia Peng, Jessica Alföldi, Kevin Gori, Amie J Eisfeld, Scott R Tyler

Nat Biotechnol· December 2014

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Gastrointestinal pathology in juvenile and adult CFTR-knockout ferrets.
Xingshen Sun, Alicia K Olivier, Yaling Yi, Christopher E Pope, Hillary S Hayden, Scott R Tyler

Am J Pathol· May 2014

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Sox2 modulates Lef-1 expression during airway submucosal gland development.
Weiliang Xie, Thomas J Lynch, Xiaoming Liu, Scott R Tyler, Shuyang Yu

Am J Physiol Lung Cell Mol Physiol· April 2014

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