Publications by authors named "Scott Snapper"

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A Collection of Patient-Derived Intestinal Organoid Lines Reveals Epithelial Phenotypes Associated with Genetic Drivers of Pediatric Inflammatory Bowel Disease.
Zahra Shojaei Jeshvaghani, Carmen Argmann, Maaike H de Vries, Johan H van Es, Lauren V Collen, Scott B Snapper

Inflamm Bowel Dis· November 2025

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A niche-dependent redox rheostat regulates epithelial stem cell fate.
Xi Chen, Krishnan Raghunathan, Bin Bao, Elsy Ngwa, Andrew Kwong, Scott B Snapper

Nat Commun· November 2025

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Human colon stem cells are the predominant epithelial responders to bacterial antigens.
Maaike H De Vries, Claartje A Meddens, Hemme J Hijma, Anne-Claire Berrens, Suze A Jansen, Scott Snapper

Front Immunol· October 2025

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Divergent T Cell Phenotypes Define Pediatric Crohn's Disease and Ulcerative Colitis.
Leonard Nettey, Hengqi Betty Zheng, Joseph C Devlin, Julie E Horowitz, Sara Rosenbaum, Scott B Snapper

medRxiv· October 2025

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Epstein-Barr Virus Exposure Precedes Crohn's Disease Development.
Anubhab Nandy, Francesca Petralia, Chad K Porter, Stephen Elledge, , Scott B Snapper

Gastroenterology· July 2025

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Baseline terminal ileal CT and MRI measurements are associated with imaging outcomes in pediatric Crohn's disease: a cohort study.
Allison D Ta, Jonathan R Dillman, Nicholas J Ollberding, Yael Haberman, Robert Baldassano, Scott Snapper

Pediatr Radiol· July 2025

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Phenome-wide association study of monogenic inflammatory bowel disease genes in diverse biobanks identifies population-specific and shared Goldilocks alleles: implications for Precision Medicine.
Michelle M Bao, Meltem Ece Kars, David Zhang, Kyle Gettler, Daniel Rader, Scott Snapper

J Crohns Colitis· July 2025

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Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during skeletal muscle regeneration.
Yue Lu, Tezin Walji, Pratima Pandey, Chuanli Zhou, Christa W Habela, Scott B Snapper

bioRxiv· June 2025

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A collection of patient-derived intestinal organoid lines reveals epithelial phenotypes associated with genetic drivers of pediatric inflammatory bowel disease.
Zahra Shojaei Jeshvaghani, Carmen Argmann, Michal Mokry, Johan H van Es, Maaike H de Vries, Scott B Snapper

bioRxiv· June 2025

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Expert recommendations to standardize transcriptomic analysis in inflammatory bowel disease clinical trials.
Bryan Linggi, Salas Azucena, Boyd Steere, Bram Verstockt, Dahham Alsoud, Scott B Snapper

J Crohns Colitis· May 2025

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Early Life Exposure to Parental Crohn's Disease Is Associated With Offspring's Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn's Disease.
Sun-Ho Lee, Maham Bushra, Lanhui Qiu, Anne M Griffiths, Williams Turpin, Scott Snapper

Gastroenterology· February 2025

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Human colon stem cells are the principal epithelial responders to bacterial antigens.
Maaike H de Vries, Claartje A Meddens, Hemme J Hijma, Anne-Claire Berrens, Suze A Jansen, Scott Snapper

bioRxiv· February 2025

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Discordance between a deep learning model and clinical-grade variant pathogenicity classification in a rare disease cohort.
Sek Won Kong, In-Hee Lee, Lauren V Collen, Michael Field, Arjun K Manrai, Scott B Snapper

NPJ Genom Med· February 2025

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Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair.
Kautilya K Jena, Julien Mambu, Daniel Boehmer, Benedetta Sposito, Virginie Millet, Scott B Snapper

Cell· December 2024

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Human ITGAV variants are associated with immune dysregulation, brain abnormalities, and colitis.
Sina Ghasempour, Neil Warner, Rei Guan, Marco M Rodari, Danton Ivanochko, Scott B Snapper

J Exp Med· December 2024

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Hospital-wide access to genomic data advanced pediatric rare disease research and clinical outcomes.
Courtney E French, Nancy C Andrews, Alan H Beggs, Philip M Boone, Catherine A Brownstein, Scott B Snapper

NPJ Genom Med· December 2024

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Spatiotemporal coordination of actin regulators generates invasive protrusions in cell-cell fusion.
Yue Lu, Tezin Walji, Benjamin Ravaux, Pratima Pandey, Changsong Yang, Scott B Snapper

Nat Cell Biol· November 2024

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Comprehensive evaluation and practical guideline of gating methods for high-dimensional cytometry data: manual gating, unsupervised clustering, and auto-gating.
Peng Liu, Yuchen Pan, Hung-Ching Chang, Wenjia Wang, Yusi Fang, Scott B Snapper

Brief Bioinform· November 2024

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Breaking Down Barriers: Epithelial Contributors to Monogenic IBD Pathogenesis.
Jodie D Ouahed, Alexandra Griffith, Lauren V Collen, Scott B Snapper

Inflamm Bowel Dis· July 2024

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Bacterial Sphingolipids Exacerbate Colitis by Inhibiting ILC3-derived IL-22 Production.
Bin Bao, Youyuan Wang, Pavl Boudreau, Xinyang Song, Meng Wu, Scott B Snapper

Cell Mol Gastroenterol Hepatol· July 2024

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Discordance between a deep learning model and clinical-grade variant pathogenicity classification in a rare disease cohort.
Sek Won Kong, In-Hee Lee, Lauren V Collen, Arjun K Manrai, Scott B Snapper

medRxiv· May 2024

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Catalyzing change: Implementing standardised reporting in monogenic inflammatory bowel disease research.
Pai-Jui Yeh, Katrina Nash, James E G Charlesworth, Lauren V Collen, Scott Snapper

J Pediatr Gastroenterol Nutr· April 2024

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Response to Letter to the Editor: "Failure Rate of Antitumor Necrosis Factor Alpha Biologics in Very Early Onset Inflammatory Bowel Disease".
Lauren V Collen, Scott B Snapper

Inflamm Bowel Dis· March 2024

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Anti-infliximab antibodies and low infliximab levels correlate with drug discontinuation in pediatric inflammatory bowel disease.
Naamah Zitomersky, Lisa Chi, Enju Liu, Kurtis R Bray, Konstantinos Papamichael, Scott B Snapper

J Pediatr Gastroenterol Nutr· February 2024

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Clinical Remission of Severe Crohn's Disease with Empagliflozin Monotherapy in a Pediatric Patient with Glycogen Storage Disease Type 1b.
Lauren V Collen, Peter E Newburger, Scott B Snapper

JPGN Rep· November 2023

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