Publications by authors named "Se In Lee"

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The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway.
Sarah Naguib, Chloe Lopez-Lee, Eileen Ruth Torres, Se-In Lee, Jingjie Zhu

Immunity· August 2025

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Astrocyte priming enhances microglial Aβ clearance and is compromised by APOE4.
Se-In Lee, Jichang Yu, Hyein Lee, Buyun Kim, Min Jun Jang

Nat Commun· August 2025

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Opposing role of phagocytic receptors MERTK and AXL in Progranulin deficient FTD.
Claire Dudley Clelland, Li Fan, Rowan Saloner, Jon Iker Etchegaray, Chad Richard Altobelli, Se-In Lee

Commun Biol· July 2025

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Imaging lipid rafts reveals the principle of ApoE4-induced Aβ upregulation in human neurons.
Se-In Lee, Heejin Lim, Na Yeon Kim, Jichang Yu, Joonho Cho, Hyein Lee

iScience· February 2025

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- mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition.
Sarah Naguib, Chloe Lopez-Lee, Eileen Ruth Torres, Se-In Lee, Jingjie Zhu

bioRxiv· January 2025

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HDAC6 preserves BNIP3 expression and mitochondrial integrity by deacetylating p53 at lysine 320.
Se-In Lee, Yuri Seo, Hoang Thi Oanh, Thi Tuyet Hanh Vo, Hyeonbin Go, Joo-Yong Lee

Biochem Biophys Res Commun· January 2024

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ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes.
Hyein Lee, Sukhee Cho, Mi-Jin Kim, Yeo Jin Park, Eunji Cho, Jung Yi Lee, Se-In Lee, Young-Sam Lee, In-Kyu Lee

Cell Rep· October 2023

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SIRT1 suppresses in vitro decidualization of human endometrial stromal cells through the downregulation of forkhead box O1 expression.
Seong-Lan Yu, Se-In Lee, Hwan-Woo Park, Sung Ki Lee, Tae-Hyun Kim

Reprod Biol· September 2022

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Synthesis and biological evaluation of 2-benzylaminoquinazolin-4(3)-one derivatives as a potential treatment for SARS-CoV-2.
Jun Young Lee, Young Sup Shin, Sangeun Jeon, Se In Lee, Jung-Eun Cho

Bull Korean Chem Soc· March 2022

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APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Aβ generation.
Se-In Lee, Woojin Jeong, Heejin Lim, Sukhee Cho, Hyein Lee

Stem Cell Reports· September 2021

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Design, synthesis and biological evaluation of 2-aminoquinazolin-4(3H)-one derivatives as potential SARS-CoV-2 and MERS-CoV treatments.
Jun Young Lee, Young Sup Shin, Sangeun Jeon, Se In Lee, Soojin Noh

Bioorg Med Chem Lett· May 2021

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A Synthetic CPP33-Conjugated Active Domain Peptide Inhibits Invasion Ability of Non-Small Lung Cancer Cells.
Seong-Lan Yu, Han Koo, Se-In Lee, JaeKu Kang, Young-Hyun Han, Dong Chul Lee

Biomolecules· November 2020

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Decursinol from Angelica gigas Nakai enhances endometrial receptivity during implantation.
Seong-Eun Kim, Joo Eun Lee, Young-Hyun Han, Se-In Lee, Do Kyung Kim

BMC Complement Med Ther· February 2020

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Postmortem proteomics to discover biomarkers for forensic PMI estimation.
Kyoung-Min Choi, Angela Zissler, Eunjung Kim, Bianca Ehrenfellner, Eunji Cho, Se-In Lee

Int J Legal Med· May 2019

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HDAC6 regulates thermogenesis of brown adipocytes through activating PKA to induce UCP1 expression.
Suna Jung, Miae Han, Sovannarith Korm, Se-In Lee, Solhee Noh, Kye-Sung Lee, Joo-Yong Lee

Biochem Biophys Res Commun· September 2018

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HDAC6 deficiency induces apoptosis in mesenchymal stem cells through p53 K120 acetylation.
Song-Yi Park, Sophors Phorl, Suna Jung, Korm Sovannarith, Se-In Lee, Joo-Yong Lee

Biochem Biophys Res Commun· December 2017

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RAP80 binds p32 to preserve the functional integrity of mitochondria.
Hee Jin Chung, Sovannarith Korm, Se-In Lee, Sophors Phorl, Solhee Noh, Joo-Yong Lee

Biochem Biophys Res Commun· October 2017

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