Publications by authors named "Sean Cutler"

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Unusually broad-spectrum small-molecule sensing using a single protein scaffold.
Hao Tian, Jesús Beltrán, Wesley George, Chase Lenert-Mondou, Norman Seder, Sean R Cutler

Proc Natl Acad Sci U S A· December 2025

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PYR1 Biosensor-Driven Genome-Wide CRISPR Screens for Improved Monoterpene Production in .
Nicholas R Robertson, Chase Lenert-Mondou, Alison C Leonard, Aida Tafrishi, Stephanie Carrera, Sean R Cutler

ACS Synth Biol· August 2025

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Synthesis of large single-transcript pathways from oligonucleotide pools: Design of STARBURST, an autobioluminescent reporter.
Gony Dvir, Zenan Xing, Irina Beldman, Andrés Rivera, Ian Wheeldon, Sean R Cutler

Proc Natl Acad Sci U S A· August 2025

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Computational design of dynamic biosensors for emerging synthetic opioids.
Alison C Leonard, Chase Lenert-Mondou, Rachel Chayer, Samuel Swift, Zachary T Baumer, Sean R Cutler

bioRxiv· May 2025

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BioCurve Analyzer: a web-based shiny app for analyzing biological response curves.
Zenan Xing, James Eckhardt, Aditya S Vaidya, Sean R Cutler

Plant Methods· April 2025

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Chemical disruption of ABA signaling overcomes high-temperature inhibition of seed germination and enhances seed priming responses.
James Eckhardt, Aditya Vaidya, Sean Cutler

PLoS One· December 2024

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Functional genomic screening in Komagataella phaffii enabled by high-activity CRISPR-Cas9 library.
Aida Tafrishi, Varun Trivedi, Zenan Xing, Mengwan Li, Ritesh Mewalal, Sean R Cutler

Metab Eng· September 2024

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Rationalizing Diverse Binding Mechanisms to the Same Protein Fold: Insights for Ligand Recognition and Biosensor Design.
Alison C Leonard, Anika J Friedman, Rachel Chayer, Brian M Petersen, Janty Woojuh, Sean R Cutler

ACS Chem Biol· August 2024

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GMMA Can Stabilize Proteins Across Different Functional Constraints.
Nicolas Daffern, Kristoffer E Johansson, Zachary T Baumer, Nicholas R Robertson, Janty Woojuh, Sean R Cutler

J Mol Biol· June 2024

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Repurposing plant hormone receptors as chemically-inducible genetic switches for dynamic regulation in yeast.
Shuang Wei, Mengwan Li, Xuye Lang, Nicholas R Robertson, Sang-Youl Park, Sean R Cutler

Metab Eng· May 2024

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An orthogonalized PYR1-based CID module with reprogrammable ligand-binding specificity.
Sang-Youl Park, Jingde Qiu, Shuang Wei, Francis C Peterson, Jesús Beltrán, Sean R Cutler

Nat Chem Biol· January 2024

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High-Performance Cannabinoid Sensor Empowered by Plant Hormone Receptors and Antifouling Magnetic Nanorods.
Zongbo Li, Yuyang Shen, Jesús Beltrán, Hao Tian, Matthew Bedewitz, Sean R Cutler

ACS Sens· October 2023

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Next-generation ABACUS biosensors reveal cellular ABA dynamics driving root growth at low aerial humidity.
James Rowe, Mathieu Grangé-Guermente, Marino Exposito-Rodriguez, Rinukshi Wimalasekera, Martin O Lenz, Sean R Cutler

Nat Plants· July 2023

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Author Correction: Tuning water-use efficiency and drought tolerance in wheat using abscisic acid receptors.
Ryosuke Mega, Fumitaka Abe, June-Sik Kim, Yuuri Tsuboi, Keisuke Tanaka, Sean R Cutler

Nat Plants· June 2023

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Selective control of parasitic nematodes using bioactivated nematicides.
Andrew R Burns, Rachel J Baker, Megan Kitner, Jessica Knox, Brittany Cooke, Sean R Cutler

Nature· June 2023

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A Closed Form Model for Molecular Ratchet-Type Chemically Induced Dimerization Modules.
Paul J Steiner, Samuel D Swift, Matthew Bedewitz, Ian Wheeldon, Sean R Cutler

Biochemistry· January 2023

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Focus on climate change and plant abiotic stress biology.
Nancy A Eckardt, Sean Cutler, Thomas E Juenger, Amy Marshall-Colon, Michael Udvardi

Plant Cell· January 2023

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Rapid biosensor development using plant hormone receptors as reprogrammable scaffolds.
Jesús Beltrán, Paul J Steiner, Matthew Bedewitz, Shuang Wei, Francis C Peterson, Sean R Cutler

Nat Biotechnol· December 2022

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Egg-laying and locomotory screens with C. elegans yield a nematode-selective small molecule stimulator of neurotransmitter release.
Sean Harrington, Jessica J Knox, Andrew R Burns, Ken-Loon Choo, Aaron Au, Sean R Cutler

Commun Biol· August 2022

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Synthesis and characterization of abscisic acid receptor modulators.
Aditya S Vaidya, Sang-Youl Park, Zenan Xing, Sean R Cutler

Methods Enzymol· July 2022

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Systematic characterization of gene function in the photosynthetic alga Chlamydomonas reinhardtii.
Friedrich Fauser, Josep Vilarrasa-Blasi, Masayuki Onishi, Silvia Ramundo, Weronika Patena, Sean R Cutler

Nat Genet· May 2022

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A thermodynamic switch modulates abscisic acid receptor sensitivity.
Florine Dupeux, Julia Santiago, Katja Betz, Jamie Twycross, Sang-Youl Park, Sean R Cutler

EMBO J· April 2022

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Chemical Approaches for Improving Plant Water Use.
Aditya S Vaidya, Sean R Cutler

Methods Mol Biol· February 2022

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Labeling Using a Clickable ER-Disrupting Probe Suggests a Role for Oleosins in Seedling ER Integrity.
Wim Dejonghe, Aditya S Vaidya, Simon E Alfred, Sean R Cutler

ACS Chem Biol· November 2021

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Click-to-lead design of a picomolar ABA receptor antagonist with potent activity in vivo.
Aditya S Vaidya, Francis C Peterson, James Eckhardt, Zenan Xing, Sang-Youl Park, Sean R Cutler

Proc Natl Acad Sci U S A· September 2021

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