Publications by authors named "Sean Jmaeff"

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Alternative Splicing of a Receptor Intracellular Domain Yields Different Ectodomain Conformations, Enabling Isoform-Selective Functional Ligands.
Fouad Brahimi, Alba Galan, Sean Jmaeff, Pablo F Barcelona, Nicolas De Jay

iScience· September 2020

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Small-Molecule Ligands that Bind the RET Receptor Activate Neuroprotective Signals Independent of but Modulated by Coreceptor GFR1.
Sean Jmaeff, Yulia Sidorova, Hayley Lippiatt, Pablo F Barcelona, Hinyu Nedev

Mol Pharmacol· July 2020

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Small-molecule agonists of the RET receptor tyrosine kinase activate biased trophic signals that are influenced by the presence of GFRa1 co-receptors.
Sean Jmaeff, Yulia Sidorova, Hinyu Nedev, Mart Saarma, H Uri Saragovi

J Biol Chem· May 2020

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In retinitis pigmentosa TrkC.T1-dependent vectorial Erk activity upregulates glial TNF-α, causing selective neuronal death.
Alba Galán, Sean Jmaeff, Pablo F Barcelona, Fouad Brahimi, Marinko V Sarunic

Cell Death Dis· December 2017

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p75 antagonists attenuate photoreceptor cell loss in murine models of retinitis pigmentosa.
María Platón-Corchado, Pablo F Barcelona, Sean Jmaeff, Miguel Marchena, Alberto M Hernández-Pinto

Cell Death Dis· July 2017

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Neurotrophin receptor agonists and antagonists as therapeutic agents: An evolving paradigm.
Sylvia Josephy-Hernandez, Sean Jmaeff, Iulia Pirvulescu, Tahar Aboulkassim, H Uri Saragovi

Neurobiol Dis· January 2017

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p75NTR and Its Ligand ProNGF Activate Paracrine Mechanisms Etiological to the Vascular, Inflammatory, and Neurodegenerative Pathologies of Diabetic Retinopathy.
Pablo F Barcelona, Nicholas Sitaras, Alba Galan, Gema Esquiva, Sean Jmaeff

J Neurosci· August 2016

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