Publications by authors named "Sean Lawler"

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Feedforward miR-181d degradation modulates population variance of methyl-guanine methyl transferase and temozolomide resistance.
Gatikrushna Singh, Shilpi Singh, Iteeshree Mohapatra, Stefan Kim, Mayur Sharma, Sean E Lawler

Cell Rep· November 2025

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A brain cancer microtissue model for studying tumor cell and neural cell interactions.
Dominick J Calvao, Francesca Vecchio, Ahbid Zein-Sabatto, Monica Ocitti, Rachel Vidomlanski, Sean E Lawler

Sci Rep· October 2025

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Trends in glioblastoma treatment, survival, and disparities in access to care in the United States from 2004 to 2019: a National Cancer Database analysis.
John Pham, Jonathan Sisti, David J Cote, Keiko Kang, Robert G Briggs, Sean E Lawler

J Neurosurg· September 2025

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Enabling CAR-T Cell Immunotherapy in Glioblastoma by Modifying Tumor Microenvironment via Oncolytic Adenovirus Encoding Bispecific T Cell Engager.
Moon Jung Choi, Eui Young So, Bedia Akosman, Young Eun Lee, Alexander G Raufi, Sean E Lawler

bioRxiv· August 2025

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Cytomegalovirus-induced oncomodulation drives immune escape in glioblastoma.
Harald Krenzlin, Felix Corr, Deepak Ailani, Philipp Einheuser, Thomas Bukur, Sean E Lawler

Sci Rep· July 2025

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Acquired resistance to molecularly targeted therapies for cancer.
Nolan M Stubbs, Tyler J Roady, Maximilian P Schwermann, Elias O Eteshola, William J MacDonald, Sean Lawler

Cancer Drug Resist· June 2025

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Tracing tumor-neuronal connectivity in glioblastoma.
Sean E Lawler

Neuro Oncol· May 2025

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ARHGAP12 and ARHGAP29 exert distinct regulatory effects on switching between two cell morphological states through GSK-3 activity.
Vinton W T Cheng, Philippa Vaughn-Beaucaire, Gary C Shaw, Malte Kriegs, Alastair Droop, Sean E Lawler

Cell Rep· March 2025

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A multi-institutional phase 1 clinical trial exploring upfront multimodal standard of care and combined immunotherapies for newly diagnosed glioblastoma.
Patrick Y Wen, Andrea Manzanera, Caroline Duault, Edgar Gonzalez-Kozlova, Lenika Lopez, Sean E Lawler

Neuro Oncol· March 2025

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Bistable dynamics of TAN-NK cells in tumor growth and control of radiotherapy-induced neutropenia in lung cancer treatment.
Donggu Lee, Sunju Oh, Sean Lawler, Yangjin Kim

Math Biosci Eng· March 2025

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Modulation of blood-tumor barrier transcriptional programs improves intratumoral drug delivery and potentiates chemotherapy in GBM.
Jorge L Jimenez-Macias, Philippa Vaughn-Beaucaire, Ayush Bharati, Zheyun Xu, Megan Forrest, Sean E Lawler

Sci Adv· February 2025

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Clinical implications of cytomegalovirus in glioblastoma progression and therapy.
Noe B Mercado, Jacqueline N Real, Jacob Kaiserman, Eleni Panagioti, Charles H Cook, Sean E Lawler

NPJ Precis Oncol· September 2024

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Modulation of blood-tumor barrier transcriptional programs improves intra-tumoral drug delivery and potentiates chemotherapy in GBM.
Jorge L Jimenez-Macias, Philippa Vaughn-Beaucaire, Ayush Bharati, Zheyun Xu, Megan Forrest, Sean E Lawler

bioRxiv· August 2024

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Directionally non-rotating electric field therapy delivered through implanted electrodes as a glioblastoma treatment platform: A proof-of-principle study.
Jun Ma, Shilpi Singh, Ming Li, Davis Seelig, Gregory F Molnar, Sean Lawler

Neurooncol Adv· July 2024

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Identification of transcriptomic signatures associated with glioblastoma recurrence.
Sean E Lawler

Neuro Oncol· June 2024

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Intracranial CAR-T cell delivery in glioblastoma patients.
Philippa Vaughn-Beaucaire, Moon Jung Choi, Olin Liang, Sean E Lawler

Trends Cancer· June 2024

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Ex vivo drug sensitivity screening predicts response to temozolomide in glioblastoma patients and identifies candidate biomarkers.
Ioannis Ntafoulis, Anne Kleijn, Jie Ju, Kevin Jimenez-Cowell, Federica Fabro, Sean E Lawler

Br J Cancer· October 2023

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PPRX-1701, a nanoparticle formulation of 6'-bromoindirubin acetoxime, improves delivery and shows efficacy in preclinical GBM models.
Mykola Zdioruk, Jorge-Luis Jimenez-Macias, Michal Oskar Nowicki, Katherine E Manz, Kurt D Pennell, Sean E Lawler

Cell Rep Med· May 2023

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Uncovering transcriptomic landscape alterations of CAN-2409 in and glioma models.
Marilin S Koch, Mykola Zdioruk, Michal O Nowicki, Michael S Hoetker, Zachary T Herbert, Sean E Lawler

Front Med (Lausanne)· May 2023

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Nucleolin promotes angiogenesis and endothelial metabolism along the oncofetal axis in the human brain vasculature.
Marc Schwab, Ignazio de Trizio, Moheb Ghobrial, Jau-Ye Shiu, Oguzkan Sürücü, Sean E Lawler

JCI Insight· April 2023

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Digging deeper for new targets in bevacizumab resistance.
Sean E Lawler

Neuro Oncol· February 2023

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Role of senescent tumor cells in building a cytokine shield in the tumor microenvironment: mathematical modeling.
Yangjin Kim, Junho Lee, Chaeyoung Lee, Sean Lawler

J Math Biol· December 2022

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Cancer immune profiling unveils biomarkers, immunological pathways, and cell type score associated with glioblastoma patients' survival.
Daniel Antunes Moreno, Luciane Sussuchi da Silva, Isabella Gomes, Letícia Ferro Leal, Gustavo Noriz Berardinelli, Sean Lawler

Ther Adv Med Oncol· December 2022

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Variants of the adeno-associated virus serotype 9 with enhanced penetration of the blood-brain barrier in rodents and primates.
Yizheng Yao, Jun Wang, Yi Liu, Yuan Qu, Kaikai Wang, Sean E Lawler

Nat Biomed Eng· November 2022

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Self-assembled ruthenium and osmium nanosystems display a potent anticancer profile by interfering with metabolic activity.
Mickaël Marloye, Haider Inam, Connor J Moore, Tyler R Mertens, Aude Ingels, Sean E Lawler

Inorg Chem Front· June 2022

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