Publications by authors named "Sean M Amberg"

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Coadministration of LHF-535 and favipiravir protects against experimental Junín virus infection and disease.
Jonna B Westover, Kevin W Bailey, Samantha R Wasson, Kirsten M Boardman, Kurt H Lustig, Sean M Amberg

Antiviral Res· September 2024

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Safety and Pharmacokinetics of LHF-535, a Potential Treatment for Lassa Fever, in Healthy Adults.
Sean M Amberg, Benjamin Snyder, Portia A Vliet-Gregg, Eric J Tarcha, Jeff Posakony

Antimicrob Agents Chemother· November 2022

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Lassa antiviral LHF-535 protects guinea pigs from lethal challenge.
Kathleen A Cashman, Eric R Wilkinson, Jeffrey Posakony, Ikenna G Madu, Eric J Tarcha, Sean M Amberg

Sci Rep· November 2022

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A potent Lassa virus antiviral targets an arenavirus virulence determinant.
Ikenna G Madu, Megan Files, Dima N Gharaibeh, Amy L Moore, Kie-Hoon Jung, Sean M Amberg

PLoS Pathog· December 2018

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Lead optimization of an acylhydrazone scaffold possessing antiviral activity against Lassa virus.
James R Burgeson, Dima N Gharaibeh, Amy L Moore, Ryan A Larson, Sean M Amberg

Bioorg Med Chem Lett· November 2013

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Discovery and optimization of potent broad-spectrum arenavirus inhibitors derived from benzimidazole.
Dongcheng Dai, James R Burgeson, Dima N Gharaibeh, Amy L Moore, Ryan A Larson, Sean M Amberg

Bioorg Med Chem Lett· February 2013

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Discovery and optimization of potent broad-spectrum arenavirus inhibitors derived from benzimidazole and related heterocycles.
James R Burgeson, Amy L Moore, Dima N Gharaibeh, Ryan A Larson, Natasha R Cerruti, Sean M Amberg

Bioorg Med Chem Lett· February 2013

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SAR analysis of a series of acylthiourea derivatives possessing broad-spectrum antiviral activity.
James R Burgeson, Amy L Moore, Jordan K Boutilier, Natasha R Cerruti, Dima N Gharaibeh, Sean M Amberg

Bioorg Med Chem Lett· July 2012

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Inhibitors of SARS-CoV entry--identification using an internally-controlled dual envelope pseudovirion assay.
Yanchen Zhou, Juliet Agudelo, Kai Lu, David H Goetz, Elizabeth Hansell, Sean M Amberg

Antiviral Res· November 2011

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Evaluation of Lassa antiviral compound ST-193 in a guinea pig model.
Kathleen A Cashman, Mark A Smith, Nancy A Twenhafel, Ryan A Larson, Kevin F Jones, Sean M Amberg

Antiviral Res· April 2011

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A specific interaction of small molecule entry inhibitors with the envelope glycoprotein complex of the Junín hemorrhagic fever arenavirus.
Celestine J Thomas, Hedi E Casquilho-Gray, Joanne York, Dianne L DeCamp, Dongcheng Dai, Sean M Amberg

J Biol Chem· February 2011

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Identification of a broad-spectrum arenavirus entry inhibitor.
Ryan A Larson, Dongcheng Dai, Virginia T Hosack, Ying Tan, Tove' C Bolken, Sean M Amberg

J Virol· November 2008

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pH-induced activation of arenavirus membrane fusion is antagonized by small-molecule inhibitors.
Joanne York, Dongcheng Dai, Sean M Amberg, Jack H Nunberg

J Virol· November 2008

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Expanded tropism and altered activation of a retroviral glycoprotein resistant to an entry inhibitor peptide.
Sean M Amberg, Robert C Netter, Graham Simmons, Paul Bates

J Virol· January 2006

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Heptad repeat 2-based peptides inhibit avian sarcoma and leukosis virus subgroup a infection and identify a fusion intermediate.
Robert C Netter, Sean M Amberg, John W Balliet, Mark J Biscone, Arwen Vermeulen

J Virol· December 2004

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Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry.
Graham Simmons, Jacqueline D Reeves, Andrew J Rennekamp, Sean M Amberg, Andrew J Piefer

Proc Natl Acad Sci U S A· March 2004

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