Publications by authors named "Sean M Post"

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Anexelekto (Axl)/Mer inhibitor tamnorzatinib in patients with relapsed/refractory acute myeloid leukaemia: Results from a phase I (monotherapy) and phase II (combination with venetoclax) clinical study.
Margaret T Kasner, Nigel Courtenay-Luck, Courtney Dinardo, Sean M Post, Praneeth Baratam

Acta Haematol· December 2025

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The tumor suppressor HNRNPK induces p53-dependent nucleolar stress to drive ribosomopathies.
Pedro Aguilar-Garrido, María Velasco-Estévez, Miguel Ángel Navarro-Aguadero, Álvaro Otero-Sobrino, Marta Ibáñez-Navarro, Sean M Post

J Clin Invest· June 2025

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Insight into the mechanism of AML del(9q) progression: hnRNP K targets the myeloid master regulators CEBPA (C/EBPα) and SPI1 (PU.1).
Kerstin Rahn, Ali T Abdallah, Lin Gan, Shelley Herbrich, Roland Sonntag, Sean M Post

Biochim Biophys Acta Gene Regul Mech· March 2024

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Comprehensive characterization of IFNγ signaling in acute myeloid leukemia reveals prognostic and therapeutic strategies.
Bofei Wang, Patrick K Reville, Mhd Yousuf Yassouf, Fatima Z Jelloul, Christopher Ly, Sean M Post

Nat Commun· February 2024

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Single-Cell Profiling of CD8+ T Cells in Acute Myeloid Leukemia Reveals a Continuous Spectrum of Differentiation and Clonal Hyperexpansion.
Poonam N Desai, Bofei Wang, Andre Fonseca, Pamella Borges, Fatima Zahra Jelloul, Sean M Post

Cancer Immunol Res· May 2023

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Assessing the role of intrinsic disorder in RNA-binding protein function: hnRNP K as a case study.
Prerna Malaney, Oscar Benitez, Xiaorui Zhang, Sean M Post

Methods· December 2022

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Heterogeneous nuclear ribonucleoprotein K is overexpressed in acute myeloid leukemia and causes myeloproliferation in mice via altered splicing.
Marisa J L Aitken, Prerna Malaney, Xiaorui Zhang, Shelley M Herbrich, Lauren Chan, Sean M Post

NAR Cancer· December 2022

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High-sensitivity next-generation sequencing MRD assessment in ALL identifies patients at very low risk of relapse.
Nicholas J Short, Hagop Kantarjian, Farhad Ravandi, Marina Konopleva, Nitin Jain, Sean M Post

Blood Adv· July 2022

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AXL/MERTK inhibitor ONO-7475 potently synergizes with venetoclax and overcomes venetoclax resistance to kill -ITD acute myeloid leukemia.
Sean M Post, Huaxian Ma, Prerna Malaney, Xiaorui Zhang, Marisa J L Aitken

Haematologica· June 2022

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GLI1 activates pro-fibrotic pathways in myelofibrosis fibrocytes.
Taghi Manshouri, Ivo Veletic, Ping Li, C Cameron Yin, Sean M Post

Cell Death Dis· May 2022

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The Eµ-hnRNP K Murine Model of Lymphoma: Novel Insights into the Role of hnRNP K in B-Cell Malignancies.
Prerna Malaney, María Velasco-Estevez, Pedro Aguilar-Garrido, Marisa J L Aitken, Lauren E Chan, Sean M Post

Front Immunol· September 2021

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Overexpression of CD200 is a Stem Cell-Specific Mechanism of Immune Evasion in AML.
Shelley Herbrich, Natalia Baran, Tianyu Cai, Connie Weng, Marisa J L Aitken, Sean M Post

J Immunother Cancer· July 2021

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TAM kinases as regulators of cell death.
Sean M Post, Michael Andreeff, Courtney DiNardo, Joseph D Khoury, Peter P Ruvolo

Biochim Biophys Acta Mol Cell Res· May 2021

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LGALS1 acts as a pro-survival molecule in AML.
Peter P Ruvolo, Huaxian Ma, Vivian R Ruvolo, Xiaorui Zhang, Sean M Post

Biochim Biophys Acta Mol Cell Res· October 2020

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Primary myelofibrosis marrow-derived CD14+/CD34- monocytes induce myelofibrosis-like phenotype in immunodeficient mice and give rise to megakaryocytes.
Taghi Manshouri, Srdan Verstovsek, David M Harris, Ivo Veletic, Xiaorui Zhang, Sean M Post

PLoS One· March 2020

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Uncovering the Role of RNA-Binding Protein hnRNP K in B-Cell Lymphomas.
Miguel Gallardo, Prerna Malaney, Marisa J L Aitken, Xiaorui Zhang, Todd M Link, Sean M Post

J Natl Cancer Inst· January 2020

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Emerging treatment options for patients with p53-pathway-deficient CLL.
Marisa J L Aitken, Hun J Lee, Sean M Post

Ther Adv Hematol· December 2019

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Proteomic Profiling of Acute Promyelocytic Leukemia Identifies Two Protein Signatures Associated with Relapse.
Fieke W Hoff, Chenyue W Hu, Amina A Qutub, Yihua Qiu, Marisa J Hornbaker, Sean M Post

Proteomics Clin Appl· July 2019

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MYC protein expression is an important prognostic factor in acute myeloid leukemia.
Maro Ohanian, Uri Rozovski, Rashmi Kanagal-Shamanna, Lynne V Abruzzo, Sanam Loghavi, Sean M Post

Leuk Lymphoma· January 2019

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Role of MSC-derived galectin 3 in the AML microenvironment.
Peter P Ruvolo, Vivian R Ruvolo, Jared K Burks, YiHua Qiu, Rui-Yu Wang, Sean M Post

Biochim Biophys Acta Mol Cell Res· July 2018

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Anexelekto/MER tyrosine kinase inhibitor ONO-7475 arrests growth and kills FMS-like tyrosine kinase 3-internal tandem duplication mutant acute myeloid leukemia cells by diverse mechanisms.
Peter P Ruvolo, Huaxian Ma, Vivian R Ruvolo, Xiaorui Zhang, Hong Mu, Sean M Post

Haematologica· December 2017

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p53 pathway dysfunction in AML: beyond mutations.
Sean M Post, Steven M Kornblau, Alfonso Quintás-Cardama

Oncotarget· December 2017

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Cancer testis antigen Sperm Protein 17 as a new target for triple negative breast cancer immunotherapy.
Leonardo Mirandola, Elisa Pedretti, Jose A Figueroa, Raffaella Chiaramonte, Michela Colombo, Sean M Post

Oncotarget· September 2017

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One size doesn't fit all in Ph-like ALL.
Sean M Post

Blood· January 2017

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Role of neoplastic monocyte-derived fibrocytes in primary myelofibrosis.
Srdan Verstovsek, Taghi Manshouri, Darrell Pilling, Carlos E Bueso-Ramos, Kate J Newberry, Sean M Post

J Exp Med· August 2016

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