Publications by authors named "Sean Marrache"

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Core hydrophobicity tuning of a self-assembled particle results in efficient lipid reduction and favorable organ distribution.
Bhabatosh Banik, Ru Wen, Sean Marrache, Anil Kumar, Nagesh Kolishetti

Nanoscale· December 2017

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Formulation and optimization of mitochondria-targeted polymeric nanoparticles.
Sean Marrache, Rakesh K Pathak, Shanta Dhar

Methods Mol Biol· October 2015

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Ex vivo generation of functional immune cells by mitochondria-targeted photosensitization of cancer cells.
Sean Marrache, Smanla Tundup, Donald A Harn, Shanta Dhar

Methods Mol Biol· October 2015

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Evaluation of nanoparticle delivered cisplatin in beagles.
Brittany Feldhaeusser, Simon R Platt, Sean Marrache, Nagesh Kolishetti, Rakesh K Pathak

Nanoscale· September 2015

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Defective hCNT1 transport contributes to gemcitabine chemoresistance in ovarian cancer subtypes: overcoming transport defects using a nanoparticle approach.
Sau Wai Hung, Sean Marrache, Shannon Cummins, Yangzom D Bhutia, Hardik Mody

Cancer Lett· April 2015

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The energy blocker inside the power house: Mitochondria targeted delivery of 3-bromopyruvate.
Sean Marrache, Shanta Dhar

Chem Sci· March 2015

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Detouring of cisplatin to access mitochondrial genome for overcoming resistance.
Sean Marrache, Rakesh K Pathak, Shanta Dhar

Proc Natl Acad Sci U S A· July 2014

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Mito-DCA: a mitochondria targeted molecular scaffold for efficacious delivery of metabolic modulator dichloroacetate.
Rakesh K Pathak, Sean Marrache, Donald A Harn, Shanta Dhar

ACS Chem Biol· May 2014

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Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studies.
Sau Wai Hung, Hardik Mody, Sean Marrache, Yangzom D Bhutia, Franklin Davis

PLoS One· April 2014

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Nanocarriers for tracking and treating diseases.
Sean Marrache, Rakesh Kumar Pathak, Kasey L Darley, Joshua H Choi, Dhillon Zaver

Curr Med Chem· February 2014

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The prodrug platin-A: simultaneous release of cisplatin and aspirin.
Rakesh K Pathak, Sean Marrache, Joshua H Choi, Trenton B Berding, Shanta Dhar

Angew Chem Int Ed Engl· February 2014

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Reply to Cormode et al.: High-density lipoprotein mimicking synthetic nanoparticle.
Sean Marrache, Shanta Dhar

Proc Natl Acad Sci U S A· September 2013

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Ex vivo programming of dendritic cells by mitochondria-targeted nanoparticles to produce interferon-gamma for cancer immunotherapy.
Sean Marrache, Smanla Tundup, Donald A Harn, Shanta Dhar

ACS Nano· August 2013

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Biodegradable synthetic high-density lipoprotein nanoparticles for atherosclerosis.
Sean Marrache, Shanta Dhar

Proc Natl Acad Sci U S A· June 2013

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Immune stimulating photoactive hybrid nanoparticles for metastatic breast cancer.
Sean Marrache, Joshua H Choi, Smanla Tundup, Dhillon Zaver, Donald A Harn

Integr Biol (Camb)· January 2013

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Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics.
Sean Marrache, Shanta Dhar

Proc Natl Acad Sci U S A· October 2012

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