Publications by authors named "Sean Oldham"

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PGC-1/Spargel Counteracts High-Fat-Diet-Induced Obesity and Cardiac Lipotoxicity Downstream of TOR and Brummer ATGL Lipase.
Soda Balla Diop, Jumana Bisharat-Kernizan, Ryan Tyge Birse, Sean Oldham, Karen Ocorr

Cell Rep· March 2015

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Obesity and nutrient sensing TOR pathway in flies and vertebrates: Functional conservation of genetic mechanisms.
Sean Oldham

Trends Endocrinol Metab· February 2011

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High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila.
Ryan T Birse, Joan Choi, Kathryn Reardon, Jessica Rodriguez, Suzanne Graham, Sean Oldham

Cell Metab· November 2010

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d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila.
Robert Wessells, Erin Fitzgerald, Nicole Piazza, Karen Ocorr, Samantha Morley, Sean Oldham

Aging Cell· September 2009

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Drosophila aging 2006/2007.
Paul Shaw, Karen Ocorr, Rolf Bodmer, Sean Oldham

Exp Gerontol· January 2008

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Bunched, the Drosophila homolog of the mammalian tumor suppressor TSC-22, promotes cellular growth.
Silvia Gluderer, Sean Oldham, Felix Rintelen, Andrea Sulzer, Corina Schütt

BMC Dev Biol· January 2008

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Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila.
Danling Wang, Li Qian, Hui Xiong, Jiandong Liu, Wendi S Neckameyer, Sean Oldham

Proc Natl Acad Sci U S A· September 2006

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Activated FOXO-mediated insulin resistance is blocked by reduction of TOR activity.
Nancy Luong, Claire R Davies, Robert J Wessells, Suzanne M Graham, M Todd King, Sean M Oldham

Cell Metab· August 2006

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TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model.
Vikram Khurana, Yiran Lu, Michelle L Steinhilb, Sean Oldham, Joshua M Shulman

Curr Biol· February 2006

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The insulin-PI3K/TOR pathway induces a HIF-dependent transcriptional response in Drosophila by promoting nuclear localization of HIF-alpha/Sima.
Andrés Dekanty, Sofía Lavista-Llanos, Maximiliano Irisarri, Sean Oldham, Pablo Wappner

J Cell Sci· December 2005

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Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control.
Sean Oldham, Ernst Hafen

Trends Cell Biol· February 2003

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The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels.
Sean Oldham, Hugo Stocker, Muriel Laffargue, Franz Wittwer, Matthias Wymann

Development· September 2002

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Living with lethal PIP3 levels: viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB.
Hugo Stocker, Mirjana Andjelkovic, Sean Oldham, Muriel Laffargue, Matthias P Wymann

Science· March 2002

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