Publications by authors named "Sean R Simpson"

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Post-resection delivery of a TLR7/8 agonist from a biodegradable scaffold achieves immune-mediated glioblastoma clearance and protection against tumor challenge in mice.
Elizabeth G Graham-Gurysh, Ryan N Woodring, Sean R Simpson, Sophie E Mendell, Nicole Rose Lukesh

Nat Commun· September 2025

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Induction of Antigen-Specific Tolerance in a Multiple Sclerosis Model without Broad Immunosuppression.
Rebeca T Stiepel, Sean R Simpson, Nicole Rose Lukesh, Denzel D Middleton, Dylan A Hendy

ACS Nano· January 2025

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Microparticles incorporating dual apoptotic factors to inhibit inflammatory effects in macrophages.
Sean R Simpson, Denzel D Middleton, Nicole Rose Lukesh, Md Jahirul Islam, Stephen A Ehrenzeller

J Pharm Sci· November 2024

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Enhancement of subunit vaccine delivery with zinc-carnosine coordination polymer through the addition of mannan.
John A Roque, Nicole Rose Lukesh, Dylan A Hendy, Timothy A Dixon, Md Jahirul Islam, Sean R Simpson

Int J Pharm· May 2024

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Immunogenicity of an adjuvanted broadly active influenza vaccine in immunocompromised and diverse populations.
Dylan A Hendy, Erik S Pena, Luis Ontiveros-Padilla, Timothy A Dixon, Denzel D Middleton, Sean R Simpson

Bioeng Transl Med· March 2024

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Development of a broadly active influenza intranasal vaccine adjuvanted with self-assembled particles composed of mastoparan-7 and CpG.
Luis Ontiveros-Padilla, Cole J Batty, Dylan A Hendy, Erik S Pena, John A Roque, Sean R Simpson

Front Immunol· April 2023

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Targeting Bcl6 in the TREX1 D18N murine model ameliorates autoimmunity by modulating T-follicular helper cells and germinal center B cells.
Rajkumar Venkatadri, Vikram Sabapathy, Murat Dogan, Saleh Mohammad, Scott E Harvey, Sean R Simpson

Eur J Immunol· May 2022

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TREX1 as a Novel Immunotherapeutic Target.
Wayne O Hemphill, Sean R Simpson, Mingyong Liu, Freddie R Salsbury, Thomas Hollis

Front Immunol· October 2021

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TREX1 - Apex predator of cytosolic DNA metabolism.
Sean R Simpson, Wayne O Hemphill, Teesha Hudson, Fred W Perrino

DNA Repair (Amst)· October 2020

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T Cells Produce IFN-α in the TREX1 D18N Model of Lupus-like Autoimmunity.
Sean R Simpson, Stephen L Rego, Scott E Harvey, Mingyong Liu, Wayne O Hemphill

J Immunol· January 2020

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TREX1 D18N mice fail to process erythroblast DNA resulting in inflammation and dysfunctional erythropoiesis.
Stephen L Rego, Scott Harvey, Sean R Simpson, Wayne O Hemphill, Zachariah A McIver

Autoimmunity· November 2018

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