Publications by authors named "Sebastiaan De Schepper"

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When the vascular lining loosens, dysfunctional macrophages permit pathological bacterial translocation in cirrhosis.
Sebastiaan De Schepper, Reiner Wiest

Gut· January 2026

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Astrocyte-derived MFG-E8 facilitates microglial synapse elimination in Alzheimer's disease mouse models.
Dimitra Sokolova, Shari Addington Ghansah, Francesca Puletti, Tatiana Georgiades, Sebastiaan De Schepper

bioRxiv· December 2024

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Author Correction: Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models.
Javier Rueda-Carrasco, Dimitra Sokolova, Sang-Eun Lee, Thomas Childs, Natália Jurčáková, Sebastiaan De Schepper

EMBO J· September 2024

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Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models.
Javier Rueda-Carrasco, Dimitra Sokolova, Sang-Eun Lee, Thomas Childs, Natália Jurčáková, Sebastiaan De Schepper

EMBO J· October 2023

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Dedicated macrophages organize and maintain the enteric nervous system.
Maria Francesca Viola, Marta Chavero-Pieres, Elodie Modave, Marcello Delfini, Nathalie Stakenborg, Sebastiaan De Schepper

Nature· June 2023

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Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease.
Sebastiaan De Schepper, Judy Z Ge, Gerard Crowley, Laís S S Ferreira, Dylan Garceau

Nat Neurosci· March 2023

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Understanding microglial diversity and implications for neuronal function in health and disease.
Sebastiaan De Schepper, Gerard Crowley, Soyon Hong

Dev Neurobiol· July 2021

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Microglia modulate neurodegeneration in Alzheimer's and Parkinson's diseases.
Tim Bartels, Sebastiaan De Schepper, Soyon Hong

Science· October 2020

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Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung.
Joey Schyns, Qiang Bai, Cecilia Ruscitti, Coraline Radermecker, Sebastiaan De Schepper

Nat Commun· September 2019

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Preoperative administration of the 5-HT4 receptor agonist prucalopride reduces intestinal inflammation and shortens postoperative ileus via cholinergic enteric neurons.
Nathalie Stakenborg, Evelien Labeeuw, Pedro J Gomez-Pinilla, Sebastiaan De Schepper, Raymond Aerts

Gut· August 2019

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A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment.
Hannah Van Hove, Liesbet Martens, Isabelle Scheyltjens, Karen De Vlaminck, Ana Rita Pombo Antunes, Sebastiaan De Schepper

Nat Neurosci· June 2019

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Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis.
Sebastiaan De Schepper, Simon Verheijden, Javier Aguilera-Lizarraga, Maria Francesca Viola, Werend Boesmans

Cell· January 2019

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Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis.
Sebastiaan De Schepper, Simon Verheijden, Javier Aguilera-Lizarraga, Maria Francesca Viola, Werend Boesmans

Cell· October 2018

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Muscularis macrophages: Key players in intestinal homeostasis and disease.
Sebastiaan De Schepper, Nathalie Stakenborg, Gianluca Matteoli, Simon Verheijden, Guy E Boeckxstaens

Cell Immunol· August 2018

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Biopsy-derived Intestinal Epithelial Cell Cultures for Pathway-based Stratification of Patients With Inflammatory Bowel Disease.
Wiebe Vanhove, Kris Nys, Ingrid Arijs, Isabelle Cleynen, Manuel Noben, Sebastiaan De Schepper

J Crohns Colitis· January 2018

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Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease.
Wiebe Vanhove, Paul M Peeters, Dominiek Staelens, Anica Schraenen, Jan Van der Goten, Sebastiaan De Schepper

Inflamm Bowel Dis· November 2015

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Neuron-macrophage crosstalk in the intestine: a "microglia" perspective.
Simon Verheijden, Sebastiaan De Schepper, Guy E Boeckxstaens

Front Cell Neurosci· November 2015

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