Publications by authors named "Sebastian Hayes"

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Itaconate confers tolerance to late NLRP3 inflammasome activation.
Monika Bambouskova, Lucie Potuckova, Tomas Paulenda, Martina Kerndl, Denis A Mogilenko, Sebastian Hayes

Cell Rep· March 2021

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MAT2A Inhibition Blocks the Growth of MTAP-Deleted Cancer Cells by Reducing PRMT5-Dependent mRNA Splicing and Inducing DNA Damage.
Peter Kalev, Marc L Hyer, Stefan Gross, Zenon Konteatis, Chi-Chao Chen, Sebastian Hayes

Cancer Cell· February 2021

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Selective Vulnerability to Pyrimidine Starvation in Hematologic Malignancies Revealed by AG-636, a Novel Clinical-Stage Inhibitor of Dihydroorotate Dehydrogenase.
Gabrielle McDonald, Victor Chubukov, John Coco, Kevin Truskowski, Rohini Narayanaswamy, Sebastian Hayes

Mol Cancer Ther· December 2020

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Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming.
Dominic G Roy, Jocelyn Chen, Victoria Mamane, Eric H Ma, Brejnev M Muhire, Sebastian Hayes

Cell Metab· February 2020

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Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production.
Brandon M Gassaway, Rebecca L Cardone, Anil K Padyana, Max C Petersen, Evan T Judd, Sebastian Hayes

Cell Rep· December 2019

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Metabolic Profiling Using Stable Isotope Tracing Reveals Distinct Patterns of Glucose Utilization by Physiologically Activated CD8 T Cells.
Eric H Ma, Mark J Verway, Radia M Johnson, Dominic G Roy, Mya Steadman, Sebastian Hayes

Immunity· November 2019

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A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition.
Christopher E Mahoney, David Pirman, Victor Chubukov, Taryn Sleger, Sebastian Hayes

Nat Commun· January 2019

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Angelman syndrome-associated point mutations in the Zn-binding N-terminal (AZUL) domain of UBE3A ubiquitin ligase inhibit binding to the proteasome.
Simone Kühnle, Gustavo Martínez-Noël, Flavien Leclere, Sebastian D Hayes, J Wade Harper

J Biol Chem· November 2018

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Connective Tissue Growth Factor Domain 4 Amplifies Fibrotic Kidney Disease through Activation of LDL Receptor-Related Protein 6.
Bryce G Johnson, Shuyu Ren, Gamze Karaca, Ivan G Gomez, Cécile Fligny, Sebastian Hayes

J Am Soc Nephrol· June 2017

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Mitochondrial Sirtuin Network Reveals Dynamic SIRT3-Dependent Deacetylation in Response to Membrane Depolarization.
Wen Yang, Koji Nagasawa, Christian Münch, Yingjie Xu, Kyle Satterstrom, Sebastian D Hayes

Cell· November 2016

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Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways.
Elizabeth T Cirulli, Brittany N Lasseigne, Slavé Petrovski, Peter C Sapp, Patrick A Dion, Sebastian D Hayes

Science· March 2015

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Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.
Jeffrey T Galligan, Gustavo Martinez-Noël, Verena Arndt, Sebastian Hayes, Thomas W Chittenden

J Proteome Res· February 2015

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Uba1 functions in Atg7- and Atg3-independent autophagy.
Tsun-Kai Chang, Bhupendra V Shravage, Sebastian D Hayes, Christine M Powers, Rachel T Simin

Nat Cell Biol· September 2013

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Comprehensive analysis of host cellular interactions with human papillomavirus E6 proteins identifies new E6 binding partners and reflects viral diversity.
Elizabeth A White, Rebecca E Kramer, Min Jie Alvin Tan, Sebastian D Hayes, J Wade Harper

J Virol· December 2012

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Direct and indirect control of mitogen-activated protein kinase pathway-associated components, BRAP/IMP E3 ubiquitin ligase and CRAF/RAF1 kinase, by the deubiquitylating enzyme USP15.
Sebastian D Hayes, Han Liu, Ewan MacDonald, Christopher M Sanderson, Judy M Coulson

J Biol Chem· December 2012

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Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions.
Sylvie Urbé, Han Liu, Sebastian D Hayes, Claire Heride, Daniel J Rigden

Mol Biol Cell· March 2012

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Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses.
Elizabeth A White, Mathew E Sowa, Min Jie Alvin Tan, Sheila Jeudy, Sebastian D Hayes

Proc Natl Acad Sci U S A· January 2012

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Cdc25A and Dub3 in a high-stakes balancing act.
Sebastian D Hayes, J Wade Harper

Nat Cell Biol· April 2010

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Ab initio protein modelling reveals novel human MIT domains.
Daniel J Rigden, Han Liu, Sebastian D Hayes, Sylvie Urbé, Michael J Clague

FEBS Lett· March 2009

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The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation.
Paula E Row, Han Liu, Sebastian Hayes, Rebecca Welchman, Panagoula Charalabous

J Biol Chem· October 2007

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