Publications by authors named "Sebastian P Fuchs"

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The Immunogenicity of AAV-Encoded HIV-1 bNAbs in Rhesus Macaques Is Unaffected by a Short Course of the Immunomodulator CTLA4Ig.
Patricia A Hahn, Siddhartha Shandilya, Lucas A B da Costa, Laura C F da Silva, Daniel O'Hagan, Sebastian P Fuchs

AIDS Res Hum Retroviruses· December 2025

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Transient rapamycin treatment avoids unwanted host immune responses toward AAV-delivered anti-HIV antibodies.
Sebastian P Fuchs, Paula G Mondragon, Rachel Zabizhin, Shallu Tomer, Li Wang

Nat Commun· October 2025

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Determinants of successful AAV-vectored delivery of HIV-1 bNAbs in early life.
Amir Ardeshir, Daniel O'Hagan, Isha Mehta, Siddhartha Shandilya, Lincoln L J Hopkins, Sebastian P Fuchs

Nature· September 2025

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In vivo evolution of env in SHIV-AD8-infected rhesus macaques after AAV-vectored delivery of eCD4-Ig.
Daniel O'Hagan, Siddhartha Shandilya, Lincoln J Hopkins, Patricia A Hahn, Sebastian P Fuchs

Mol Ther· February 2025

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High concordance of ELISA and neutralization assays allows for the detection of antibodies to individual AAV serotypes.
Matthew R Gardner, Desiree E Mendes, Claudia P Muniz, José M Martinez-Navio, Sebastian P Fuchs

Mol Ther Methods Clin Dev· March 2022

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Long-Term Delivery of an Anti-SIV Monoclonal Antibody With AAV.
José M Martinez-Navio, Sebastian P Fuchs, Desiree E Mendes, Eva G Rakasz, Guangping Gao

Front Immunol· March 2021

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Glycoengineering of AAV-delivered monoclonal antibodies yields increased ADCC activity.
James M Termini, José M Martinez-Navio, Guangping Gao, Sebastian P Fuchs, Ronald C Desrosiers

Mol Ther Methods Clin Dev· March 2021

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Liver-Directed but Not Muscle-Directed AAV-Antibody Gene Transfer Limits Humoral Immune Responses in Rhesus Monkeys.
Sebastian P Fuchs, José M Martinez-Navio, Eva G Rakasz, Guangping Gao, Ronald C Desrosiers

Mol Ther Methods Clin Dev· March 2020

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Induction of Transient Virus Replication Facilitates Antigen-Independent Isolation of SIV-Specific Monoclonal Antibodies.
Nuria Pedreño-Lopez, Christine M Dang, Brandon C Rosen, Michael J Ricciardi, Varian K Bailey, Sebastian P Fuchs

Mol Ther Methods Clin Dev· March 2020

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Circumventing cellular immunity by miR142-mediated regulation sufficiently supports rAAV-delivered OVA expression without activating humoral immunity.
Yuanyuan Xiao, Manish Muhuri, Shaoyong Li, Wanru Qin, Guangchao Xu, Sebastian P Fuchs

JCI Insight· May 2019

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Anti-drug Antibody Responses Impair Prophylaxis Mediated by AAV-Delivered HIV-1 Broadly Neutralizing Antibodies.
Matthew R Gardner, Ina Fetzer, Lisa M Kattenhorn, Meredith E Davis-Gardner, Amber S Zhou, Sebastian P Fuchs

Mol Ther· March 2019

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Adeno-Associated Virus Delivery of Anti-HIV Monoclonal Antibodies Can Drive Long-Term Virologic Suppression.
José M Martinez-Navio, Sebastian P Fuchs, Shara N Pantry, William A Lauer, Natasha N Duggan

Immunity· March 2019

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Potent Plasmablast-Derived Antibodies Elicited by the National Institutes of Health Dengue Vaccine.
Diogo M Magnani, Cassia G T Silveira, Michael J Ricciardi, Lucas Gonzalez-Nieto, Núria Pedreño-Lopez, Sebastian P Fuchs

J Virol· November 2017

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Dengue Virus Evades AAV-Mediated Neutralizing Antibody Prophylaxis in Rhesus Monkeys.
Diogo M Magnani, Michael J Ricciardi, Varian K Bailey, Martin J Gutman, Núria Pedreño-Lopez, Sebastian P Fuchs

Mol Ther· October 2017

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Recombinant AAV Vectors for Enhanced Expression of Authentic IgG.
Sebastian P Fuchs, José M Martinez-Navio, Guangping Gao, Ronald C Desrosiers

PLoS One· July 2017

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A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus.
Diogo M Magnani, Cassia G T Silveira, Brandon C Rosen, Michael J Ricciardi, Núria Pedreño-Lopez, Sebastian P Fuchs

PLoS Negl Trop Dis· June 2017

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Promise and problems associated with the use of recombinant AAV for the delivery of anti-HIV antibodies.
Sebastian P Fuchs, Ronald C Desrosiers

Mol Ther Methods Clin Dev· November 2016

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Host Anti-antibody Responses Following Adeno-associated Virus-mediated Delivery of Antibodies Against HIV and SIV in Rhesus Monkeys.
José M Martinez-Navio, Sebastian P Fuchs, Sònia Pedreño-López, Eva G Rakasz, Guangping Gao

Mol Ther· February 2016

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AAV-Delivered Antibody Mediates Significant Protective Effects against SIVmac239 Challenge in the Absence of Neutralizing Activity.
Sebastian P Fuchs, José M Martinez-Navio, Michael Piatak, Jeffrey D Lifson, Guangping Gao

PLoS Pathog· August 2015

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AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges.
Matthew R Gardner, Lisa M Kattenhorn, Hema R Kondur, Markus von Schaewen, Tatyana Dorfman, Sebastian P Fuchs

Nature· March 2015

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