Publications by authors named "Sebastien Hutter"

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Synthesis of Nitrostyrylthiazolidine-2,4-dione Derivatives Displaying Antileishmanial Potential.
Omar Khoumeri, Sébastien Hutter, Nicolas Primas, Caroline Castera-Ducros, Sandra Carvalho

Pharmaceuticals (Basel)· July 2024

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Novel thienopyrimidones targeting hepatic and erythrocytic stages of Plasmodium parasites with increased microsomal stability.
Prisca Lagardère, Romain Mustière, Nadia Amanzougaghene, Sébastien Hutter, Marion Casanova

Eur J Med Chem· December 2023

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New antiplasmodial 4-amino-thieno[3,2-d]pyrimidines with improved intestinal permeability and microsomal stability.
Prisca Lagardère, Romain Mustière, Nadia Amanzougaghene, Sébastien Hutter, Marion Casanova

Eur J Med Chem· March 2023

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Synthesis of antiplasmodial 2-aminothieno[3,2-d]pyrimidin-4(3H)-one analogues using the scaffold hopping strategy.
Romain Mustière, Prisca Lagardère, Sébastien Hutter, Viviana Dell'Orco, Nadia Amanzougaghene

Eur J Med Chem· November 2022

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Improving Aqueous Solubility and In Vitro Pharmacokinetic Properties of the 3-Nitroimidazo[1,2-]pyridine Antileishmanial Pharmacophore.
Romain Paoli-Lombardo, Nicolas Primas, Sandra Bourgeade-Delmas, Sébastien Hutter, Alix Sournia-Saquet

Pharmaceuticals (Basel)· August 2022

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Pd-catalyzed C-C and C-N cross-coupling reactions in 2-aminothieno[3,2-]pyrimidin-4(3)-one series for antiplasmodial pharmacomodulation.
Romain Mustière, Prisca Lagardère, Sébastien Hutter, Céline Deraeve, Florian Schwalen

RSC Adv· July 2022

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4-Substituted Thieno[3,2-]pyrimidines as Dual-Stage Antiplasmodial Derivatives.
Prisca Lagardère, Romain Mustière, Nadia Amanzougaghene, Sébastien Hutter, Jean-François Franetich

Pharmaceuticals (Basel)· July 2022

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Treating leishmaniasis in Amazonia, part 2: Multi-target evaluation of widely used plants to understand medicinal practices.
Emeline Houël, Marine Ginouves, Nadine Azas, Eliane Bourreau, Véronique Eparvier, Sébastien Hutter

J Ethnopharmacol· May 2022

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Antiviral Activity of Repurposing Ivermectin against a Panel of 30 Clinical SARS-CoV-2 Strains Belonging to 14 Variants.
Océane Delandre, Mathieu Gendrot, Priscilla Jardot, Marion Le Bideau, Manon Boxberger, Sébastien Hutter

Pharmaceuticals (Basel)· April 2022

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Antiplasmodial 2-thiophenoxy-3-trichloromethyl quinoxalines target the apicoplast of Plasmodium falciparum.
Dyhia Amrane, Nicolas Primas, Christophe-Sébastien Arnold, Sébastien Hutter, Béatrice Louis

Eur J Med Chem· November 2021

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A New Thienopyrimidinone Chemotype Shows Multistage Activity against Plasmodium falciparum, Including Artemisinin-Resistant Parasites.
Henriette Bosson-Vanga, Nicolas Primas, Jean-François Franetich, Catherine Lavazec, Lina Gomez, Sébastien Hutter

Microbiol Spectr· October 2021

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In Vitro Evaluation of the Antiviral Activity of Methylene Blue Alone or in Combination against SARS-CoV-2.
Mathieu Gendrot, Priscilla Jardot, Océane Delandre, Manon Boxberger, Julien Andreani, Sébastien Hutter

J Clin Med· July 2021

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2-Phenoxy-3-Trichloromethylquinoxalines Are Antiplasmodial Derivatives with Activity against the Apicoplast of .
Dyhia Amrane, Christophe-Sébastien Arnold, Sébastien Hutter, Julen Sanz-Serrano, Miguel Collia

Pharmaceuticals (Basel)· July 2021

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Methylene blue inhibits replication of SARS-CoV-2 in vitro.
Mathieu Gendrot, Julien Andreani, Isabelle Duflot, Manon Boxberger, Marion Le Bideau, Sébastien Hutter

Int J Antimicrob Agents· December 2020

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Antikinetoplastid SAR study in 3-nitroimidazopyridine series: Identification of a novel non-genotoxic and potent anti-T. b. brucei hit-compound with improved pharmacokinetic properties.
Cyril Fersing, Clotilde Boudot, Romain Paoli-Lombardo, Nicolas Primas, Emilie Pinault, Sébastien Hutter

Eur J Med Chem· November 2020

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Antimalarial artemisinin-based combination therapies (ACT) and COVID-19 in Africa: In vitro inhibition of SARS-CoV-2 replication by mefloquine-artesunate.
Mathieu Gendrot, Isabelle Duflot, Manon Boxberger, Océane Delandre, Priscilla Jardot, Sébastien Hutter

Int J Infect Dis· October 2020

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Antimalarial drugs inhibit the replication of SARS-CoV-2: An in vitro evaluation.
Mathieu Gendrot, Julien Andreani, Manon Boxberger, Priscilla Jardot, Isabelle Fonta, Sébastien Hutter

Travel Med Infect Dis· October 2020

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In Vitro Antiviral Activity of Doxycycline against SARS-CoV-2.
Mathieu Gendrot, Julien Andreani, Priscilla Jardot, Sébastien Hutter, Océane Delandre

Molecules· October 2020

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8-Alkynyl-3-nitroimidazopyridines display potent antitrypanosomal activity against both T. b. brucei and cruzi.
Cyril Fersing, Clotilde Boudot, Caroline Castera-Ducros, Emilie Pinault, Sébastien Hutter

Eur J Med Chem· September 2020

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Synthesis and Antiplasmodial Evaluation of 4-Carboxamido- and 4-Alkoxy-2-Trichloromethyl Quinazolines.
Dyhia Amrane, Armand Gellis, Sébastien Hutter, Marion Prieri, Pierre Verhaeghe

Molecules· August 2020

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Nongenotoxic 3-Nitroimidazo[1,2-]pyridines Are NTR1 Substrates That Display Potent Antileishmanial Activity.
Cyril Fersing, Louise Basmaciyan, Clotilde Boudot, Julien Pedron, Sébastien Hutter

ACS Med Chem Lett· January 2019

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8-Aryl-6-chloro-3-nitro-2-(phenylsulfonylmethyl)imidazo[1,2-a]pyridines as potent antitrypanosomatid molecules bioactivated by type 1 nitroreductases.
Cyril Fersing, Clotilde Boudot, Julien Pedron, Sébastien Hutter, Nicolas Primas

Eur J Med Chem· September 2018

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Synthesis and Antimalarial Activity of New Enantiopure Aminoalcoholpyrrolo[ 1,2-a]quinoxalines.
Alexia Jonet, Jean Guillon, Catherine Mullie, Anita Cohen, Guillaume Bentzinger, Sebastien Hutter

Med Chem· August 2018

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Novel 8-nitroquinolin-2(1H)-ones as NTR-bioactivated antikinetoplastid molecules: Synthesis, electrochemical and SAR study.
Julien Pedron, Clotilde Boudot, Sébastien Hutter, Sandra Bourgeade-Delmas, Jean-Luc Stigliani

Eur J Med Chem· July 2018

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Discovery of new hit-molecules targeting Plasmodium falciparum through a global SAR study of the 4-substituted-2-trichloromethylquinazoline antiplasmodial scaffold.
Justine Desroches, Charline Kieffer, Nicolas Primas, Sébastien Hutter, Armand Gellis

Eur J Med Chem· January 2017

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