Publications by authors named "Sefan Asamitsu"

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RNA G-quadruplexes form scaffolds that promote neuropathological α-synuclein aggregation.
Kazuya Matsuo, Sefan Asamitsu, Kohei Maeda, Hiroyoshi Suzuki, Kosuke Kawakubo

Cell· November 2024

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Modulation of dynamic DNA G-quadruplex structures in the hTERT promoter region by ligands.
Deepak Karna, Lin Liang, Grinsun Sharma, Shankar Mandal, Sefan Asamitsu

Nucleic Acids Res· October 2024

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Structural polymorphism of the nucleic acids in pentanucleotide repeats associated with the neurological disorder CANVAS.
Kenta Kudo, Karin Hori, Sefan Asamitsu, Kohei Maeda, Yukari Aida

J Biol Chem· April 2024

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A cyclic pyrrole-imidazole polyamide reduces pathogenic RNA in CAG/CTG triplet repeat neurological disease models.
Susumu Ikenoshita, Kazuya Matsuo, Yasushi Yabuki, Kosuke Kawakubo, Sefan Asamitsu

J Clin Invest· November 2023

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RNA G-quadruplex organizes stress granule assembly through DNAPTP6 in neurons.
Sefan Asamitsu, Yasushi Yabuki, Kazuya Matsuo, Moe Kawasaki, Yuki Hirose

Sci Adv· February 2023

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Small molecule-based detection of non-canonical RNA G-quadruplex structures that modulate protein translation.
Yousuke Katsuda, Shin-Ichi Sato, Maimi Inoue, Hisashi Tsugawa, Takuto Kamura, Sefan Asamitsu

Nucleic Acids Res· August 2022

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Strong and Specific Recognition of CAG/CTG Repeat DNA (5'-dWGCWGCW-3') by a Cyclic Pyrrole-Imidazole Polyamide.
Yuki Hirose, Tomo Ohno, Sefan Asamitsu, Kaori Hashiya, Toshikazu Bando

Chembiochem· January 2022

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Potential roles of G-quadruplex structures in RNA granules for physiological and pathological phase separation.
Sefan Asamitsu, Norifumi Shioda

J Biochem· July 2021

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CGG repeat RNA G-quadruplexes interact with FMRpolyG to cause neuronal dysfunction in fragile X-related tremor/ataxia syndrome.
Sefan Asamitsu, Yasushi Yabuki, Susumu Ikenoshita, Kosuke Kawakubo, Moe Kawasaki

Sci Adv· January 2021

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Pharmacological prospects of G-quadruplexes for neurological diseases using porphyrins.
Sefan Asamitsu, Yasushi Yabuki, Susumu Ikenoshita, Takahito Wada, Norifumi Shioda

Biochem Biophys Res Commun· October 2020

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Identification and immunohistochemical characterization of G-quadruplexes in mouse brain.
Sefan Asamitsu, Yoshiki Imai, Yasushi Yabuki, Susumu Ikenoshita, Masayuki Takeuchi

Biochem Biophys Res Commun· October 2020

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A synthetic transcription factor pair mimic for precise recruitment of an epigenetic modifier to the targeted DNA locus.
Zutao Yu, Mengting Ai, Soumen K Samanta, Fumitaka Hashiya, Junichi Taniguchi, Sefan Asamitsu

Chem Commun (Camb)· February 2020

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[The potential of G-quadruplexes as a therapeutic target for neurological diseases].
Norifumi Shioda, Yasushi Yabuki, Sefan Asamitsu

Nihon Yakurigaku Zasshi· December 2019

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Control of Forward/Reverse Orientation Preference of Cyclic Pyrrole-Imidazole Polyamides.
Yuki Hirose, Sefan Asamitsu, Toshikazu Bando, Hiroshi Sugiyama

J Am Chem Soc· August 2019

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Switching Off Cancer-Causing Telomerase Using Small Molecules.
Sefan Asamitsu, Norifumi Shioda, Hiroshi Sugiyama

Cell Chem Biol· August 2019

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Orientation preferences of hairpin pyrrole-imidazole polyamides toward CGG site.
Shinsuke Sato, Sefan Asamitsu, Toshikazu Bando, Hiroshi Sugiyama

Bioorg Med Chem· June 2019

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Perspectives for Applying G-Quadruplex Structures in Neurobiology and Neuropharmacology.
Sefan Asamitsu, Masayuki Takeuchi, Susumu Ikenoshita, Yoshiki Imai, Hirohito Kashiwagi

Int J Mol Sci· June 2019

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Ligand Design to Acquire Specificity to Intended G-Quadruplex Structures.
Sefan Asamitsu, Toshikazu Bando, Hiroshi Sugiyama

Chemistry· January 2019

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Recent Progress of Targeted G-Quadruplex-Preferred Ligands Toward Cancer Therapy.
Sefan Asamitsu, Shunsuke Obata, Zutao Yu, Toshikazu Bando, Hiroshi Sugiyama

Molecules· January 2019

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Orthogonal γPNA Dimerization Domains Empower DNA Binders with Cooperativity and Versatility Mimicking that of Transcription Factor Pairs.
Zutao Yu, Wei-Che Hsieh, Sefan Asamitsu, Kaori Hashiya, Toshikazu Bando

Chemistry· September 2018

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Simultaneous Binding of Hybrid Molecules Constructed with Dual DNA-Binding Components to a G-Quadruplex and Its Proximal Duplex.
Sefan Asamitsu, Shunsuke Obata, Anh Tuân Phan, Kaori Hashiya, Toshikazu Bando

Chemistry· March 2018

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G-Quadruplex Induction by the Hairpin Pyrrole-Imidazole Polyamide Dimer.
Shunsuke Obata, Sefan Asamitsu, Kaori Hashiya, Toshikazu Bando, Hiroshi Sugiyama

Biochemistry· February 2018

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DNA Interstrand Crosslinks by H-pin Polyamide (S)-seco-CBI Conjugates.
Chuanxin Guo, Sefan Asamitsu, Gengo Kashiwazaki, Shinsuke Sato, Toshikazu Bando

Chembiochem· January 2017

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Comparative Analysis of DNA-Binding Selectivity of Hairpin and Cyclic Pyrrole-Imidazole Polyamides Based on Next-Generation Sequencing.
Gengo Kashiwazaki, Anandhakumar Chandran, Sefan Asamitsu, Takashi Kawase, Yusuke Kawamoto

Chembiochem· September 2016

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Sequence-specific DNA binding by long hairpin pyrrole-imidazole polyamides containing an 8-amino-3,6-dioxaoctanoic acid unit.
Yoshito Sawatani, Gengo Kashiwazaki, Anandhakumar Chandran, Sefan Asamitsu, Chuanxin Guo

Bioorg Med Chem· August 2016

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