Publications by authors named "Sei Higuchi"

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Python-derived 16α-Hydroxylated Bile Acid, Pythocholic Acid is a ligand for TGR5, not farnesoid X receptors and vitamin D receptors.
Nicole Kiaei, Afsin Malik, Sydney O Idahosa, Kevin K Lee, Kaori Endo-Umeda, Sei Higuchi

Biochem Biophys Res Commun· March 2025

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Evidence and Mechanism of Bile Acid-Mediated Gut-Brain Axis in Anxiety and Depression.
Sydney O Idahosa, Rokia Diarra, Hernoor K Ranu, Raidah H Nasiri, Sei Higuchi

Am J Pathol· February 2025

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The 16α-hydroxylated Bile Acid, Pythocholic Acid Decreases Food Intake and Increases Oleoylethanolamide in Male Mice.
Sei Higuchi, Courtney Wood, Raidah H Nasiri, Leela J Giddla, Valentina Molina

Endocrinology· August 2023

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Sex-specific differences in metabolic outcomes after sleeve gastrectomy and intermittent fasting in obese middle-aged mice.
Ana B Emiliano, Natalie R Lopatinsky, Marko Kraljević, Sei Higuchi, Ying He

Am J Physiol Endocrinol Metab· July 2022

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FOXO1 Is Present in Stomach Epithelium and Determines Gastric Cell Distribution.
Wendy M McKimpson, Taiyi Kuo, Takumi Kitamoto, Sei Higuchi, Jason C Mills

Gastro Hep Adv· May 2022

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Cyp2c-deficiency depletes muricholic acids and protects against high-fat diet-induced obesity in male mice but promotes liver damage.
Antwi-Boasiako Oteng, Sei Higuchi, Alexander S Banks, Rebecca A Haeusler

Mol Metab· November 2021

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Bile acid composition regulates GPR119-dependent intestinal lipid sensing and food intake regulation in mice.
Sei Higuchi, Tiara R Ahmad, Donovan A Argueta, Pedro A Perez, Chen Zhao

Gut· September 2020

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Bile acid composition regulates the manganese transporter Slc30a10 in intestine.
Tiara R Ahmad, Sei Higuchi, Enrico Bertaggia, Allison Hung, Niroshan Shanmugarajah

J Biol Chem· August 2020

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The Physiological Importance of Bile Acid Structure and Composition on Glucose Homeostasis.
Sei Higuchi

Curr Diab Rep· July 2020

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Characterization and pharmacokinetic evaluation of microcomposite particles of alpha lipoic acid/hydrogenated colza oil obtained in supercritical carbon dioxide.
Masatoshi Honjo, Okuhara Yasuhide, Masayoshi Yamada, Sei Higuchi, Kenji Mishima

Pharm Dev Technol· March 2020

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EP receptor-associated protein regulates gluconeogenesis in the liver and is associated with hyperglycemia in diabetic mice.
Sei Higuchi, Risako Fujikawa, Masato Nakatsuji, Mika Yasui, Taichi Ikedo

Am J Physiol Endocrinol Metab· March 2019

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Unexplained reciprocal regulation of diabetes and lipoproteins.
Sei Higuchi, M Concepción Izquierdo, Rebecca A Haeusler

Curr Opin Lipidol· June 2018

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[EPRAP: a key regulator of inflammation].
Risako Fujikawa, Sei Higuchi, Masato Nakatsuji, Mika Yasui, Masayuki Yokode

Nihon Yakurigaku Zasshi· November 2017

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Deficiency in EP4 Receptor-Associated Protein Ameliorates Abnormal Anxiety-Like Behavior and Brain Inflammation in a Mouse Model of Alzheimer Disease.
Risako Fujikawa, Sei Higuchi, Masato Nakatsuji, Mika Yasui, Taichi Ikedo

Am J Pathol· August 2017

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Dipeptidyl Peptidase-4 Inhibitor Anagliptin Prevents Intracranial Aneurysm Growth by Suppressing Macrophage Infiltration and Activation.
Taichi Ikedo, Manabu Minami, Hiroharu Kataoka, Kosuke Hayashi, Manabu Nagata, Sei Higuchi

J Am Heart Assoc· June 2017

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Behavioral abnormalities and reduced norepinephrine in EP4 receptor-associated protein (EPRAP)-deficient mice.
Risako Fujikawa, Sei Higuchi, Taichi Ikedo, Manabu Nagata, Kosuke Hayashi

Biochem Biophys Res Commun· April 2017

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EP4 Receptor-Associated Protein in Macrophages Protects against Bleomycin-Induced Pulmonary Inflammation in Mice.
Sei Higuchi, Risako Fujikawa, Taichi Ikedo, Kosuke Hayashi, Mika Yasui

J Immunol· December 2016

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EP4 Receptor-Associated Protein in Microglia Promotes Inflammation in the Brain.
Risako Fujikawa, Sei Higuchi, Masato Nakatsuji, Mika Yasui, Taichi Ikedo

Am J Pathol· August 2016

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Expression of Vasohibin-1 in Human Carotid Atherosclerotic Plaque.
Ryu Fukumitsu, Manabu Minami, Kazumichi Yoshida, Manabu Nagata, Mika Yasui, Sei Higuchi

J Atheroscler Thromb· July 2016

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The Prostaglandin E2 Receptor EP4 Regulates Obesity-Related Inflammation and Insulin Sensitivity.
Mika Yasui, Yukinori Tamura, Manabu Minami, Sei Higuchi, Risako Fujikawa

PLoS One· May 2016

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EP4 Receptor-Associated Protein in Macrophages Ameliorates Colitis and Colitis-Associated Tumorigenesis.
Masato Nakatsuji, Manabu Minami, Hiroshi Seno, Mika Yasui, Hideyuki Komekado, Sei Higuchi

PLoS Genet· October 2015

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Hypothalamic 2-arachidonoylglycerol regulates multistage process of high-fat diet preferences.
Sei Higuchi, Keiichi Irie, Ryuji Yamaguchi, Mai Katsuki, Maiko Araki

PLoS One· December 2012

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Reducing acyl migration during purification of 2-arachidonoylglycerol from biological samples before gas chromatography mass spectrometry analysis.
Sei Higuchi, Keiichi Irie, Takafumi Nakano, Yuya Sakamoto, Yoshiharu Akitake

Anal Sci· June 2011

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Increment of hypothalamic 2-arachidonoylglycerol induces the preference for a high-fat diet via activation of cannabinoid 1 receptors.
Sei Higuchi, Makiko Ohji, Maiko Araki, Riyo Furuta, Mai Katsuki

Behav Brain Res· January 2011

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The cannabinoid 1-receptor silent antagonist O-2050 attenuates preference for high-fat diet and activated astrocytes in mice.
Sei Higuchi, Keiichi Irie, Shohei Mishima, Maiko Araki, Makiko Ohji

J Pharmacol Sci· October 2010

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