Publications by authors named "Seiichi Ishida"

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Stable and functional human intestinal epithelium derived from induced pluripotent stem cells.
Junlong Chen, So Kuramochi, Shinichiro Horiuchi, Tomoyuki Kawasaki, Hiroto Kakizaki, Seiichi Ishida

Drug Metab Dispos· November 2025

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Considerations for developing CYP induction assays in hepatocytes: Insights from a multilaboratory study.
Hiroko Toyoda, Ayaka Nozue, Yuki Nishida, Yasuko Yakabe, Yasuhiko Aiki, Seiichi Ishida

Eur J Cell Biol· September 2025

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Biology-inspired dynamic microphysiological system approaches to revolutionize basic research, healthcare and animal welfare.
Uwe Marx, Sonja Beken, Zaozao Chen, Eva-Maria Dehne, Ann Doherty, Seiichi Ishida

ALTEX· April 2025

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Global expansion of microphysiological systems (MPS) and Japan's initiatives: Innovation in pharmaceutical development and path to regulatory acceptance.
Daiju Yamazaki, Seiichi Ishida

Drug Metab Pharmacokinet· February 2025

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[Approaches to Improving Human Extrapolation of Drug Evaluation Methods].
Daiju Yamazaki, Seiichi Ishida

Yakugaku Zasshi· January 2025

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Formation of functional, extended bile canaliculi, and increased bile acid production in sandwich-cultured human cryopreserved hepatocytes using commercially available culture medium.
Shinichiro Horiuchi, Yukie Kuroda, Ryota Oyafuso, Yuji Komizu, Kazuya Maeda, Seiichi Ishida

Arch Toxicol· August 2024

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Selective elimination of tumorigenic cells from mixed culture of normal and tumorigenic cells using hybrid liposomes aimed at realizing of cell therapy.
Riko Jinno, Moe Tanaka, Yuji Komizu, Yoko Matsumoto, Taku Matsushita, Seiichi Ishida

Cytotechnology· April 2024

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Novel Screening System for Biliary Excretion of Drugs Using Human Cholangiocyte Organoid Monolayers with Directional Drug Transport.
Kenta Mizoi, Ryo Okada, Arisa Mashimo, Norio Masuda, Manabu Itoh, Seiichi Ishida

Biol Pharm Bull· February 2024

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Human intestinal organoid-derived PDGFRα + mesenchymal stroma enables proliferation and maintenance of LGR4 + epithelial stem cells.
JunLong Chen, Shinichiro Horiuchi, So Kuramochi, Tomoyuki Kawasaki, Hayato Kawasumi, Seiichi Ishida

Stem Cell Res Ther· January 2024

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Label-Free Evaluation of Maturation and Hepatotoxicity of Human iPSC-Derived Hepatocytes Using Hyperspectral Raman Imaging.
Menglu Li, Yukiko Ueyama-Toba, Matthew Lindley, Gunganist Kongklad, Yasunori Nawa, Seiichi Ishida

Anal Chem· June 2023

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Construction of extended and functional bile canaliculi using long-term sandwich-cultured cryopreserved human hepatocytes and the application of hepatocytes for predicting the biliary excretion of pharmaceutical and food-related compounds.
Takashi Kitaguchi, Shinichiro Horiuchi, Yukie Kuroda, Katsutoshi Ohno, Kazuhiro Kobayashi, Seiichi Ishida

J Toxicol Sci· May 2023

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Usefulness of a humanized tricellular static transwell blood-brain barrier model as a microphysiological system for drug development applications. - A case study based on the benchmark evaluations of blood-brain barrier microphysiological system.
Kimiko Nakayama-Kitamura, Yukari Shigemoto-Mogami, Hiroko Toyoda, Ikue Mihara, Hiroyuki Moriguchi, Seiichi Ishida

Regen Ther· March 2023

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[Accelerate New Drug Development by Imitating the Biological Environment in Micro-space-The Cutting Edge of MPS from Japan].
Daiju Yamazaki, Seiichi Ishida

Yakugaku Zasshi· January 2023

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Consideration of Commercially Available Hepatocytes as Cell Sources for Liver-Microphysiological Systems by Comparing Liver Characteristics.
Shinichiro Horiuchi, Yukie Kuroda, Yuji Komizu, Seiichi Ishida

Pharmaceutics· December 2022

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Construction of a culture protocol for functional bile canaliculi formation to apply human iPS cell-derived hepatocytes for cholestasis evaluation.
Shinichiro Horiuchi, Yukie Kuroda, Ryota Oyafuso, Yuji Komizu, Takashi Takaki, Seiichi Ishida

Sci Rep· September 2022

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Label-free chemical imaging of cytochrome P450 activity by Raman microscopy.
Menglu Li, Yasunori Nawa, Seiichi Ishida, Yasunari Kanda, Satoshi Fujita

Commun Biol· August 2022

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Transcriptional and Epigenetic Consequences of DMSO Treatment on HepaRG Cells.
Hélène Dubois-Pot-Schneider, Caroline Aninat, Kathrin Kattler, Karim Fekir, Kathleen Jarnouen, Seiichi Ishida

Cells· July 2022

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Directional Drug Transport through Membrane-Supported Monolayers of Human Liver-Derived Cell Lines.
Kenta Mizoi, Misako Kobayashi, Arisa Mashimo, Eiko Matsumoto, Norio Masuda, Seiichi Ishida

Biol Pharm Bull· April 2022

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A physiologically based kinetic modeling of ethyl tert-butyl ether in humans-An illustrative application of quantitative structure-property relationship and Monte Carlo simulation.
Saori Watanabe-Matsumoto, Kikuo Yoshida, Yuriko Meiseki, Seiichi Ishida, Akihiko Hirose

J Toxicol Sci· February 2022

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Recent Progress in Prediction Systems for Drug-induced Liver Injury Using In vitro Cell Culture.
Shogo Ozawa, Toshitaka Miura, Jun Terashima, Wataru Habano, Seiichi Ishida

Drug Metab Lett· January 2022

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Research and Development of Microphysiological Systems in Japan Supported by the AMED-MPS Project.
Seiichi Ishida

Front Toxicol· April 2021

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Culture density contributes to hepatic functions of fresh human hepatocytes isolated from chimeric mice with humanized livers: Novel, long-term, functional two-dimensional in vitro tool for developing new drugs.
Chihiro Yamasaki, Yuji Ishida, Ami Yanagi, Yasumi Yoshizane, Yuha Kojima, Seiichi Ishida

PLoS One· October 2020

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Immortalization of human hepatocytes from biliary atresia with CDK4, cyclin D1, and TERT for cytochrome P450 induction testing.
Manami Nishiwaki, Masashi Toyoda, Yoshie Oishi, Seiichi Ishida, Shin-Ichiro Horiuchi

Sci Rep· October 2020

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Generation of Human iPSC-Derived Intestinal Epithelial Cell Monolayers by CDX2 Transduction.
Kazuo Takayama, Ryosuke Negoro, Tomoki Yamashita, Kanae Kawai, Moe Ichikawa, Seiichi Ishida

Cell Mol Gastroenterol Hepatol· July 2020

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[Microphysiological system as a promising technology for drug assay].
Seiichi Ishida, Toshiyuki Kanamori

Nihon Yakurigaku Zasshi· December 2019

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