Publications by authors named "Seitaro Mutoh"

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Pharmacological profile of FK881(ASP6537), a novel potent and selective cyclooxygenase-1 inhibitor.
Junko Imanishi, Yoshiaki Morita, Eiji Yoshimi, Kanae Kuroda, Tomoko Masunaga, Seitaro Mutoh

Biochem Pharmacol· October 2011

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Prevention of renal interstitial fibrosis via histone deacetylase inhibition in rats with unilateral ureteral obstruction.
Fumitaka Kinugasa, Takahisa Noto, Hideaki Matsuoka, Yasuharu Urano, Yuji Sudo, Seitaro Mutoh

Transpl Immunol· May 2010

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ASP4000, a slow-binding dipeptidyl peptidase 4 inhibitor, has antihyperglycemic activity of long duration in Zucker fatty rats.
Keiko Tanaka-Amino, Kazumi Matsumoto, Yoshifumi Hatakeyama, Shoji Takakura, Seitaro Mutoh

Acta Diabetol· March 2010

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Constitutive increase in active GLP-1 levels by the DPP4 inhibitor ASP4000 on a new meal tolerance test in Zucker fatty rats.
Keiko Tanaka-Amino, Yoshifumi Hatakeyama, Shoji Takakura, Seitaro Mutoh

Pharmacol Res· October 2009

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Effect of the immunosuppressant histone deacetylase inhibitor FR276457 in a canine renal transplant model.
Fumitaka Kinugasa, Itsuo Nagatomi, Tomonori Nakanishi, Takahisa Noto, Hiroaki Mori, Seitaro Mutoh

Transpl Immunol· September 2009

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Tacrolimus (FK506) suppresses rt-PA-induced hemorrhagic transformation in a rat thrombotic ischemia stroke model.
Masashi Maeda, Yasuhisa Furuichi, Takahisa Noto, Nobuya Matsuoka, Seitaro Mutoh

Brain Res· February 2009

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Thirteen-month inhibition of aldose reductase by zenarestat prevents morphological abnormalities in the dorsal root ganglia of streptozotocin-induced diabetic rats.
Yukinori Shimoshige, Kyoko Minoura, Nobuya Matsuoka, Shoji Takakura, Seitaro Mutoh

Brain Res· January 2009

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FK1706, a novel non-immunosuppressive immunophilin ligand, modifies the course of painful diabetic neuropathy.
Shunji Yamazaki, Takayuki Yamaji, Nobuhito Murai, Hiroko Yamamoto, Raymond D Price, Seitaro Mutoh

Neuropharmacology· December 2008

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Efficacy of oral treatment with tacrolimus in the renal transplant model in cynomolgus monkeys.
Fumitaka Kinugasa, Itsuo Nagatomi, Hirofumi Ishikawa, Tomonori Nakanishi, Masashi Maeda, Seitaro Mutoh

J Pharmacol Sci· December 2008

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FK1706, a novel non-immunosuppressant neurophilin ligand, ameliorates motor dysfunction following spinal cord injury through its neuroregenerative action.
Takayuki Yamaji, Shunji Yamazaki, Jiyao Li, Raymond D Price, Nobuya Matsuoka, Seitaro Mutoh

Eur J Pharmacol· September 2008

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Effect of a new immunosuppressant histon deacetylase (HDAC) inhibitor FR276457 in a rat cardiac transplant model.
Fumitaka Kinugasa, Toshiko Yamada, Takahisa Noto, Hideaki Matsuoka, Hiroaki Mori, Seitaro Mutoh

Biol Pharm Bull· September 2008

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Use of a serum-based antifungal susceptibility assay to predict the in vivo efficacy of novel echinocandin compounds.
Katsuyuki Maki, Satoru Matsumoto, Etsuko Watabe, Yumi Iguchi, Masaki Tomishima, Seitaro Mutoh

Microbiol Immunol· August 2008

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Direct comparison of the pharmacodynamics of four antifungal drugs in a mouse model of disseminated candidiasis using microbiological assays of serum drug concentrations.
Katsuyuki Maki, Ann R Holmes, Etsuko Watabe, Yumi Iguchi, Satoru Matsumoto, Seitaro Mutoh

Microbiol Immunol· May 2008

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Novel method for selecting immunosuppressive histone deacetylase (HDAC) inhibitors with minimal thrombocytopenia.
Hideaki Matsuoka, Takao Fujimura, Akira Unami, Toshiko Yamada, Takahisa Noto, Seitaro Mutoh

Biol Pharm Bull· February 2008

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Mechanism of HDAC inhibitor FR235222-mediated IL-2 transcriptional repression in Jurkat cells.
Hideaki Matsuoka, Takao Fujimura, Hiroaki Mori, Ichiro Aramori, Seitaro Mutoh

Int Immunopharmacol· November 2007

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Mechanisms of HDAC inhibitor-induced thrombocytopenia.
Hideaki Matsuoka, Akira Unami, Takao Fujimura, Takahisa Noto, Yoko Takata, Seitaro Mutoh

Eur J Pharmacol· October 2007

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Disruption of HDAC4/N-CoR complex by histone deacetylase inhibitors leads to inhibition of IL-2 gene expression.
Hideaki Matsuoka, Takao Fujimura, Masako Hayashi, Kaori Matsuda, Yoshinori Ishii, Seitaro Mutoh

Biochem Pharmacol· August 2007

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Therapeutic time window of tacrolimus (FK506) in a nonhuman primate stroke model: comparison with tissue plasminogen activator.
Yasuhisa Furuichi, Masashi Maeda, Nobuya Matsuoka, Seitaro Mutoh, Takehiko Yanagihara

Exp Neurol· March 2007

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Tacrolimus (FK506) limits accumulation of granulocytes and platelets and protects against brain damage after transient focal cerebral ischemia in rat.
Takahisa Noto, Yasuhisa Furuichi, Masayuki Ishiye, Nobuya Matsuoka, Ichiro Aramori, Seitaro Mutoh

Biol Pharm Bull· February 2007

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A selective peroxisome proliferator-activated receptor gamma modulator with distinct fat cell regulation properties.
Takao Fujimura, Chiaki Kimura, Tomoya Oe, Yoko Takata, Hiroyuki Sakuma, Seitaro Mutoh

J Pharmacol Exp Ther· August 2006

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Temporal and topographic profiles of tissue hypoxia following transient focal cerebral ischemia in rats.
Takahisa Noto, Yasuhisa Furuichi, Masayuki Ishiye, Nobuya Matsuoka, Ichiro Aramori, Seitaro Mutoh

J Vet Med Sci· August 2006

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Determination of antifungal activities in serum samples from mice treated with different antifungal drugs allows detection of an active metabolite of itraconazole.
Katsuyuki Maki, Etsuko Watabe, Yumi Iguchi, Hideko Nakamura, Masaki Tomishima, Seitaro Mutoh

Microbiol Immunol· June 2006

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Inhibitory effect of zacopride on Cisplatin-induced delayed emesis in ferrets.
Hisashi Yamakuni, Hiroe Nakayama, Shigeo Matsui, Katsunori Imazumi, Masahiko Matsuo, Seitaro Mutoh

J Pharmacol Sci· May 2006

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Unique properties of coactivator recruitment caused by differential binding of FK614, an anti-diabetic agent, to peroxisome proliferator-activated receptor gamma.
Takao Fujimura, Hiroyuki Sakuma, Akiko Ohkubo-Suzuki, Ichiro Aramori, Seitaro Mutoh

Biol Pharm Bull· March 2006

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FR177391, a new anti-hyperlipidemic agent from Serratia. II. Pharmacological activity of FR177391.
Masamichi Inami, Ikuo Kawamura, Susumu Tsujimoto, Tohru Yasuno, Elizabeth Lacey, Seitaro Mutoh

J Antibiot (Tokyo)· October 2005

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