Publications by authors named "Senthil K Radhakrishnan"

Claim this Profile
A
Anthracyclines attenuate Nrf1-dependent proteolytic pathways and potentiate proteasome inhibitor cytotoxicity.
Janakiram R Vangala, Madison A Ward, Bader Albalawi, Ahmed M Elshazly, Nayyerehalsadat Hosseini, Senthil K Radhakrishnan

Mol Biol Cell· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting SUMOylation promotes cBAF complex stabilization and disruption of the SS18::SSX transcriptome in synovial sarcoma.
Konstantinos V Floros, Carter K Fairchild, Jinxiu Li, Kun Zhang, Jane L Roberts, Senthil K Radhakrishnan

Nat Commun· November 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Proteasome Inhibition Enhances Lysosome-mediated Targeted Protein Degradation.
Ahmed M Elshazly, Nayyerehalsadat Hosseini, Shanwei Shen, Victoria Neely, Hisashi Harada, Senthil K Radhakrishnan

bioRxiv· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Oncogenic Mutant p53 Sensitizes Non-Small Cell Lung Cancer Cells to Proteasome Inhibition via Oxidative Stress-Dependent Induction of Mitochondrial Apoptosis.
Kranthi Kumar Chougoni, Victoria Neely, Boxiao Ding, Eziafa Oduah, Vianna T Lam, Senthil K Radhakrishnan

Cancer Res Commun· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy.
Madison A Ward, Janakiram R Vangala, Hatem Elif Kamber Kaya, Holly A Byers, Nayyerehalsadat Hosseini, Senthil K Radhakrishnan

J Cell Biol· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in Synovial Sarcoma.
Konstantinos V Floros, Carter K Fairchild, Jinxiu Li, Kun Zhang, Jane L Roberts, Senthil K Radhakrishnan

Res Sq· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting.
Jerry Li, Nicholas Purser, Joanna Liwocha, Daniel C Scott, Holly A Byers, Senthil K Radhakrishnan

Mol Cell· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in Synovial Sarcoma.
Konstantinos V Floros, Carter K Fairchild, Jinxiu Li, Kun Zhang, Jane L Roberts, Senthil K Radhakrishnan

bioRxiv· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Human Intermediate Prolactin Receptor I-tail Contributes Breast Oncogenesis by Targeting Ras/MAPK Pathway.
Shanwei Shen, Senthil K Radhakrishnan, J Chuck Harrell, Madhavi Puchalapalli, Jennifer Koblinski

Endocrinology· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evaluation of the NRF1-proteasome axis as a therapeutic target in breast cancer.
Holly A Byers, Amy N Brooks, Janakiram R Vangala, Jacqueline M Grible, Alex Feygin, Senthil K Radhakrishnan

Sci Rep· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Trash Talk: Mammalian Proteasome Regulation at the Transcriptional Level.
Hatem Elif Kamber Kaya, Senthil K Radhakrishnan

Trends Genet· February 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Regulation of NRF1, a master transcription factor of proteasome genes: implications for cancer and neurodegeneration.
Amy Northrop, Holly A Byers, Senthil K Radhakrishnan

Mol Biol Cell· September 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Liver-specific deletion of Ngly1 causes abnormal nuclear morphology and lipid metabolism under food stress.
Haruhiko Fujihira, Yuki Masahara-Negishi, Yoshihiro Akimoto, Hiroto Hirayama, Hyeon-Cheol Lee, Senthil K Radhakrishnan

Biochim Biophys Acta Mol Basis Dis· March 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
BET Inhibitors Synergize with Carfilzomib to Induce Cell Death in Cancer Cells via Impairing Nrf1 Transcriptional Activity and Exacerbating the Unfolded Protein Response.
Janakiram R Vangala, Ajay Potluri, Senthil K Radhakrishnan

Biomolecules· March 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Disabling the Protease DDI2 Attenuates the Transcriptional Activity of NRF1 and Potentiates Proteasome Inhibitor Cytotoxicity.
Amy Northrop, Janakiram R Vangala, Alex Feygin, Senthil K Radhakrishnan

Int J Mol Sci· January 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Nrf1-mediated transcriptional regulation of the proteasome requires a functional TIP60 complex.
Janakiram R Vangala, Senthil K Radhakrishnan

J Biol Chem· February 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity.
Frederick M Tomlin, Ulla I M Gerling-Driessen, Yi-Chang Liu, Ryan A Flynn, Janakiram R Vangala, Senthil K Radhakrishnan

ACS Cent Sci· November 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Nrf1 can be processed and activated in a proteasome-independent manner.
Janakiram R Vangala, Franziska Sotzny, Elke Krüger, Raymond J Deshaies, Senthil K Radhakrishnan

Curr Biol· September 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition.
Senthil K Radhakrishnan, Willem den Besten, Raymond J Deshaies

Elife· November 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells.
Senthil K Radhakrishnan, Candy S Lee, Patrick Young, Anne Beskow, Jefferson Y Chan

Mol Cell· April 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
FOXM1: the Achilles' heel of cancer?
Senthil K Radhakrishnan, Andrei L Gartel

Nat Rev Cancer· March 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of a chemical inhibitor of the oncogenic transcription factor forkhead box M1.
Senthil K Radhakrishnan, Uppoor G Bhat, Douglas E Hughes, I-Ching Wang, Robert H Costa

Cancer Res· October 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pro-apoptotic role of NF-kappaB: implications for cancer therapy.
Senthil K Radhakrishnan, Sitharthan Kamalakaran

Biochim Biophys Acta· August 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel transcriptional inhibitor induces apoptosis in tumor cells and exhibits antiangiogenic activity.
Senthil K Radhakrishnan, Andrei L Gartel

Cancer Res· March 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CDK9 phosphorylates p53 on serine residues 33, 315 and 392.
Senthil K Radhakrishnan, Andrei L Gartel

Cell Cycle· March 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis