Publications by authors named "Senthilkumar Rajappa"

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BEES-HAUS preventing urethral stricture recurrence by restoring the integrity of urothelium and its further simplified version, the BHES-HAUS.
Akio Horiguchi, Surya Prakash Vaddi, Senthilkumar Rajappa, Senthilkumar Preethy, Samuel J K Abraham

Front Bioeng Biotechnol· December 2025

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Effects of Nichi BRITE β-glucans as an onco-nutrition adjuvant in patients undergoing subtotal stomach-preserving pancreaticoduodenectomy (SSPPD) for pancreatic, bile duct and duodenal malignancies: A clinical study.
Akira Tsukada, Isao Miyajima, Satomi Uchiyama, Daiki Tabe, Nobunao Ikewaki, Rajappa Senthilkumar

Nutrition· September 2025

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Comment on "Comparative efficacy of autologous adult live cultured buccal epithelial cells (AALBEC) and minced buccal mucosal graft endourethral urethroplasty (MBGEU) in male urethral stricture" by Singh K et al.
Vaddi Suryaprakash, Akio Horiguchi, Rajappa Senthilkumar, Senthilkumar Preethy, Samuel J K Abraham

Int Urol Nephrol· July 2025

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Modulation of neutrophil-to-lymphocyte ratio and gut microbiome balance in astronauts: potential benefits of novel beta-glucans during space missions.
Nobunao Ikewaki, Koji Ichiyama, Rajappa Senthilkumar, Senthilkumar Preethy, Samuel J K Abraham

Front Immunol· March 2025

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Enhanced expression of dystrophin, IGF-1, CD44 and MYH3 in plasma and skeletal muscles including diaphragm of mdx mice after oral administration of Neu REFIX beta 1,3-1,6 glucan.
Senthilkumar Preethy, Shuji Sakamoto, Takuma Higuchi, Koji Ichiyama, Naoki Yamamoto, Rajappa Senthilkumar

Sci Rep· February 2025

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Commentary: The ME-BYO index: A development and validation project of a novel comprehensive health index.
Nobunao Ikewaki, Koji Ichiyama, Rajappa Senthilkumar, Senthilkumar Preethy, Samuel J K Abraham

Front Public Health· January 2025

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Human corneal endothelial cell transplantation with nanocomposite gel sheet preserves corneal stability in post-corneal transplant bullous keratopathy: a 16-year follow-up.
Periasamy Parikumar, Kazutoshi Haraguchi, Rajappa Senthilkumar, Samuel Jk Abraham

Am J Stem Cells· June 2024

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Efficacy of N-163 beta-glucan in beneficially improving biomarkers of relevance to muscle function in patients with muscular dystrophies in a pilot clinical study.
Kadalraja Raghavan, Thanasekar Sivakumar, Koji Ichiyama, Naoki Yamamoto, Mangaleswaran Balamurugan, Rajappa Senthilkumar

Acta Myol· February 2024

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Corrigendum to "Beneficial immune-modulatory effects of the N-163 strain of Aureobasidium pullulans-produced 1,3-1,6 Beta glucans in Duchenne muscular dystrophy: Results of an open-label, prospective, exploratory case-control clinical study" [IBRO Neurosci. Rep. 15 (2023), pp. 90-99].
Kadalraja Raghavan, Vidyasagar Devaprasad Dedeepiya, Subramaniam Srinivasan, Subramanian Pushkala, Sudhakar S Bharatidasan, Rajappa Senthilkumar

IBRO Neurosci Rep· December 2023

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Beneficial immune-modulatory effects of the N-163 strain of -produced 1,3-1,6 Beta glucans in Duchenne muscular dystrophy: Results of an open-label, prospective, exploratory case-control clinical study.
Kadalraja Raghavan, Vidyasagar Devaprasad Dedeepiya, Subramaniam Srinivasan, Subramanian Pushkala, Sudhakar S Bharatidasan, Rajappa Senthilkumar

IBRO Neurosci Rep· December 2023

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Resolution of fibrosis in mdx dystrophic mouse after oral consumption of N-163 strain of Aureobasidium pullulans produced β-glucan.
Senthilkumar Preethy, Yoshitsugu Aoki, Katsura Minegishi, Masaru Iwasaki, Rajappa Senthilkumar

Sci Rep· October 2023

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Benefits of Gut Microbiota Reconstitution by Beta 1,3-1,6 Glucans in Subjects with Autism Spectrum Disorder and Other Neurodegenerative Diseases.
Kadalraja Raghavan, Vidyasagar Devaprasad Dedeepiya, Naoki Yamamoto, Nobunao Ikewaki, Tohru Sonoda, Rajappa Senthilkumar

J Alzheimers Dis· August 2023

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Engraftment and Proliferation of Thermoreversible-Gelation-Polymer-Encapsulated Human Corneal Limbal-Stem-Cells on Ocular Surface of a Cadaver Cornea.
Rajappa Senthilkumar, Hiroshi Yoshioka, Shojiro Katoh, Masaru Iwasaki, Vaddi Surya Prakash

Curr Eye Res· June 2023

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Beneficial effects of 1,3-1,6 β-glucans produced by Aureobasidium pullulans on non-esterified fatty acid levels in diabetic KKAy mice and their potential implications in metabolic dysregulation.
Nobunao Ikewaki, Yasunori Ikeue, Mitsuru Nagataki, Gene Kurosawa, Vidyasagar Devaprasad Dedeepiya, Rajappa Senthilkumar

J Diabetes Metab Disord· June 2023

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Engraftment of Transplanted Buccal Epithelial Cells onto the Urethrotomy Site, Proven Immunohistochemically in Rabbit Model; a Feat to Prevent Urethral Stricture Recurrence.
Akio Horiguchi, Masayuki Shinchi, Kenichiro Ojima, Yusuke Hirano, Toshihiro Kushibiki, Rajappa Senthilkumar

Stem Cell Rev Rep· January 2023

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Two unique biological response-modifier glucans beneficially regulating gut microbiota and faecal metabolome in a non-alcoholic steatohepatitis animal model, with potential applications in human health and disease.
Senthilkumar Preethy, Nobunao Ikewaki, Gary A Levy, Kadalraja Raghavan, Vidyasagar Devaprasad Dedeepiya, Rajappa Senthilkumar

BMJ Open Gastroenterol· September 2022

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Beneficial Immune Regulation by Biological Response Modifier Glucans in COVID-19 and Their Envisaged Potentials in the Management of Sepsis.
Senthilkumar Preethy, Kadalraja Raghavan, Vidyasagar Devaprasad Dedeepiya, Vaddi Surya Prakash, Nobunao Ikewaki, Rajappa Senthilkumar

Front Immunol· July 2022

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Hepatoprotective Effects of Derived β 1,3-1,6 Glucans in a Murine Model of Non-alcoholic Steatohepatitis.
Nobunao Ikewaki, Gary A Levy, Gene Kurosawa, Masaru Iwasaki, Vidyasagar D Dedeepiya, Rajappa Senthilkumar

J Clin Exp Hepatol· June 2022

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Culture Expansion and Characterization of Buccal Mucosal Epithelial Cells for Tissue Engineering Applications in Urethral Stricture After Transportation Using a Thermoreversible Gelation Polymer.
Akio Horiguchi, Kenichiro Ojima, Masayuki Shinchi, Yoshine Mayumi, Toshihiro Kushibiki, Rajappa Senthilkumar

Biopreserv Biobank· February 2022

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β‑glucan vaccine adjuvant approach for cancer treatment through immune enhancement (B‑VACCIEN) in specific immunocompromised populations (Review).
Nobunao Ikewaki, Vidyasagar Devaprasad Dedeepiya, Kadalraja Raghavan, Kosagi-Sharaf Rao, Suryaprakash Vaddi, Rajappa Senthilkumar

Oncol Rep· January 2022

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Beneficial effects of novel aureobasidium pullulans strains produced beta-1,3-1,6 glucans on interleukin-6 and D-dimer levels in COVID-19 patients; results of a randomized multiple-arm pilot clinical study.
Kadalraja Raghavan, Vidyasagar Devaprasad Dedeepiya, Vaddi Suryaprakash, Kosagi-Sharaf Rao, Nobunao Ikewaki, Rajappa Senthilkumar

Biomed Pharmacother· January 2022

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An efficient polymer cocktail-based transportation method for cartilage tissue, yielding chondrocytes with enhanced hyaline cartilage expression during in vitro culturing.
Shojiro Katoh, Hiroshi Yoshioka, Shoji Suzuki, Hiroyuki Nakajima, Masaru Iwasaki, Rajappa Senthilkumar

J Orthop· January 2022

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Enhanced miRNA-140 expression of osteoarthritis-affected human chondrocytes cultured in a polymer based three-dimensional (3D) matrix.
Shojiro Katoh, Hiroshi Yoshioka, Rajappa Senthilkumar, Senthilkumar Preethy, Samuel J K Abraham

Life Sci· August 2021

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Reversal of senescence-associated beta-galactosidase expression during in vitro three-dimensional tissue-engineering of human chondrocytes in a polymer scaffold.
Shojiro Katoh, Atsuki Fujimaru, Masaru Iwasaki, Hiroshi Yoshioka, Rajappa Senthilkumar

Sci Rep· July 2021

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A 3D Polymer Scaffold Platform for Enhanced Culture of Human & Rabbit Buccal Epithelial Cells for Cell Therapies.
Shojiro Katoh, Srinivas K Rao, Vaddi Suryaprakash, Akio Horiguchi, Toshihiro Kushibiki, Rajappa Senthilkumar

Tokai J Exp Clin Med· April 2021

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