Publications by authors named "Senthilkumar Ramamoorthy"

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Synonymous and non-synonymous variants at splice junctions can disrupt splicing and are frequently linked to disease associated loss of function genes.
Sruthi Srinivasan, Swetha Subramanian, Hui Zhou, Anselm Hoppmann, Patrick Metzger, Senthilkumar Ramamoorthy

BMC Genomics· December 2025

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Assessment of peripheral blood DNA methylation signatures as pharmacodynamic and predictive biomarkers during azacitidine therapy in juvenile myelomonocytic leukaemia: Results of the EWOG-MESRAT study.
Maximilian Schönung, Silvia Rathmann, Senthilkumar Ramamoorthy, Dirk Lebrecht, Thomas Klingebiel

Br J Haematol· October 2025

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Long-term outcomes of patients with refractory cytopenia of childhood under observation only.
Beatrice Drexler, Stephan Schwarz-Furlan, Irith Baumann, Martina Rudelius, Peter Nöllke, Senthilkumar Ramamoorthy

Blood Adv· August 2025

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Comparative Profiling of Regulatory Modules as a Tool for Identifying the Transcription Factor Network Linked to Leukemogenesis.
Swetha Subramanian, Yutthaphong Phongbunchoo, Pierre Cauchy, Senthilkumar Ramamoorthy

Methods Mol Biol· May 2025

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Oncogenic and microenvironmental signals drive cell type specific apoptosis resistance in juvenile myelomonocytic leukemia.
Naile Koleci, Ying Wu, Niels Anton Wehner, Jovana Rajak, Venugopal Rao Mittapalli, Senthilkumar Ramamoorthy

Cell Death Dis· March 2025

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YY1-mediated enhancer-promoter communication in the immunoglobulin μ locus is regulated by MSL/MOF recruitment.
Yutthaphong Phongbunchoo, Fatima-Zohra Braikia, Cecilia Pessoa-Rodrigues, Senthilkumar Ramamoorthy, Haribaskar Ramachandran

Cell Rep· July 2024

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Assessment of a novel NRAS in-frame tandem duplication causing a myelodysplastic/myeloproliferative neoplasm.
Cora C A Beckmann, Senthilkumar Ramamoorthy, Eirini Trompouki, Wolfgang Driever, Stephan Schwarz-Furlan

Exp Hematol· May 2024

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Spontaneous remission and loss of monosomy 7: a window of opportunity for young children with SAMD9L syndrome.
Miriam Erlacher, Felicia Andresen, Martina Sukova, Jan Stary, Barbara De Moerloose, Senthilkumar Ramamoorthy

Haematologica· February 2024

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Biallelic inactivation of the NF1 tumour suppressor gene in juvenile myelomonocytic leukaemia: Genetic evidence of driver function and implications for diagnostic workup.
Senthilkumar Ramamoorthy, Dirk Lebrecht, Denny Schanze, Ina Schanze, Ilse Wieland

Br J Haematol· February 2024

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Activation of gp130 signaling in T cells drives T17-mediated multi-organ autoimmunity.
Francis Baumgartner, Stefanos A Bamopoulos, Laura Faletti, Hsiang-Jung Hsiao, Maximilian Holz, Senthilkumar Ramamoorthy

Sci Signal· February 2024

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Integrin β1 regulates marginal zone B cell differentiation and PI3K signaling.
Virginia Andreani, Senthilkumar Ramamoorthy, Reinhard Fässler, Rudolf Grosschedl

J Exp Med· January 2023

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DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity.
Roshni Roy, Senthilkumar Ramamoorthy, Benjamin D Shapiro, Mary Kaileh, Dena Hernandez

Immunity· June 2022

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Dynamics of nuclear matrix attachment regions during 5 instar posterior silk gland development in Bombyx mori.
Alekhya Rani Chunduri, Resma Rajan, Anugata Lima, Senthilkumar Ramamoorthy, Anitha Mamillapalli

BMC Genomics· March 2022

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DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity.
Roshni Roy, Senthilkumar Ramamoorthy, Benjamin D Shapiro, Mary Kaileh, Dena Hernandez

Immunity· November 2021

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ZFP451-mediated SUMOylation of SATB2 drives embryonic stem cell differentiation.
Gustavo Antonio Urrutia, Haribaskar Ramachandran, Pierre Cauchy, Kyungjin Boo, Senthilkumar Ramamoorthy

Genes Dev· August 2021

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EBF1 and Pax5 safeguard leukemic transformation by limiting IL-7 signaling, Myc expression, and folate metabolism.
Senthilkumar Ramamoorthy, Kohei Kometani, Josip S Herman, Marc Bayer, Sören Boller

Genes Dev· November 2020

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EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential.
Marta Derecka, Josip Stefan Herman, Pierre Cauchy, Senthilkumar Ramamoorthy, Ekaterina Lupar

Nat Immunol· March 2020

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Cochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin function.
Virginia Andreani, Senthilkumar Ramamoorthy, Abhinav Pandey, Ekaterina Lupar, Stephen L Nutt

Proc Natl Acad Sci U S A· October 2018

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Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B-cell programming.
Rui Li, Pierre Cauchy, Senthilkumar Ramamoorthy, Sören Boller, Lukas Chavez

Genes Dev· January 2018

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Interaction of CCR4-NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis.
Cheng-Yuan Yang, Senthilkumar Ramamoorthy, Sören Boller, Marc Rosenbaum, Alfonso Rodriguez Gil

Genes Dev· October 2016

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Pioneering Activity of the C-Terminal Domain of EBF1 Shapes the Chromatin Landscape for B Cell Programming.
Sören Boller, Senthilkumar Ramamoorthy, Duygu Akbas, Robert Nechanitzky, Lukas Burger

Immunity· March 2016

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Expansion of the polycomb system and evolution of complexity.
Divya Tej Sowpati, Senthilkumar Ramamoorthy, Rakesh K Mishra

Mech Dev· November 2015

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Length and sequence dependent accumulation of simple sequence repeats in vertebrates: potential role in genome organization and regulation.
Senthilkumar Ramamoorthy, Hita Sony Garapati, Rakesh Kumar Mishra

Gene· November 2014

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Transcription factor EBF1 is essential for the maintenance of B cell identity and prevention of alternative fates in committed cells.
Robert Nechanitzky, Duygu Akbas, Stefanie Scherer, Ildiko Györy, Thomas Hoyler, Senthilkumar Ramamoorthy

Nat Immunol· August 2013

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Functional diversification of yeast telomere associated protein, Rif1, in higher eukaryotes.
Easwaran Sreesankar, Ramamoorthy Senthilkumar, Vellaichamy Bharathi, Rakesh K Mishra, Krishnaveni Mishra

BMC Genomics· June 2012

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