Publications by authors named "Sergio A Gradilone"

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Loss of Aquaporin-1 in Tumor Cells Fosters Intrahepatic Cholangiocarcinoma Progression.
César I Gaspari, Carine Beaupere, Seth Richard, Estanislao Peixoto, Bouchra Lekbaby, Sergio A Gradilone

Am J Pathol· November 2025

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The chromatin regulator HELLS mediates SSB repair and responses to DNA alkylation damage.
Joyous T Joseph, Christine M Wright, Estanislao Peixoto, Etsuko Shibata, Asad Khan, Sergio A Gradilone

Nucleic Acids Res· November 2025

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Primary Cilia in Hepatic Biliary Hyperplasia: Implications for Liver Diseases.
Kishor Pant, Estanislao Peixoto, Sergio A Gradilone

Semin Liver Dis· September 2025

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Cholangiocytes' primary cilia regulate DNA damage response and repair.
Estanislao Peixoto, Kishor Pant, Seth Richard, Juan Pablo Popoca, Juan E Abrahante, Sergio A Gradilone

Am J Physiol Gastrointest Liver Physiol· September 2025

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Cholangiocyte ciliary defects induce sustained epidermal growth factor receptor signaling.
Kishor Pant, Seth Richard, Estanislao Peixoto, Subheksha Baral, Rendong Yang, Sergio A Gradilone

Hepatology· April 2025

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Chromatin regulator HELLS mediates SSB repair and responses to DNA alkylation damage.
Joyous T Joseph, Christine M Wright, Estanislao Peixoto, Etsuko Shibata, Asad Khan, Sergio A Gradilone

bioRxiv· April 2025

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Cholangiocytes' Primary Cilia Regulate DNA Damage Response and Repair.
Estanislao Peixoto, Kishor Pant, Seth Richard, Juan E Abrahante, Wioletta Czaja, Sergio A Gradilone

bioRxiv· February 2025

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Tiny sentinels: how cilia guard the kidneys in ischaemia-reperfusion injury.
Estanislao Peixoto, Lily Flaherty, Sergio A Gradilone

J Physiol· October 2024

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NAMPT Overexpression Drives Cell Growth in Polycystic Liver Disease through Mitochondrial Metabolism Regulation.
Kishor Pant, Sergio A Gradilone

Am J Pathol· August 2024

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Myeloid differentiation factor-2/LY96, a potential predictive biomarker of metastasis and poor outcomes in prostate cancer: clinical implications as a potential therapeutic target.
Marina G Ferrari, Alexis P Jimenez-Uribe, Li Wang, Luke H Hoeppner, Paari Murugan, Sergio A Gradilone

Oncogene· February 2024

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The Role of Gut Microbiome-Derived Short-Chain Fatty Acid Butyrate in Hepatobiliary Diseases.
Kishor Pant, Senthil K Venugopal, Maria J Lorenzo Pisarello, Sergio A Gradilone

Am J Pathol· October 2023

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Cilia and Cancer: From Molecular Genetics to Therapeutic Strategies.
Pietro Carotenuto, Sergio A Gradilone, Brunella Franco

Genes (Basel)· July 2023

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The NAMPT Inhibitor FK866 in Combination with Cisplatin Reduces Cholangiocarcinoma Cells Growth.
Kishor Pant, Seth Richard, Estanislao Peixoto, Jun Yin, Davis M Seelig, Sergio A Gradilone

Cells· February 2023

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Hepatobiliary Cancers: Progress in Diagnosis, Pathogenesis, and Treatment.
Kishor Pant, Sergio A Gradilone

Technol Cancer Res Treat· May 2022

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Inhibition of triple‑negative breast cancer proliferation and motility by reactivating p53 and inhibiting overactivated Akt.
Wei Cao, Renhui Shen, Seth Richard, Yu Liu, Mohammad Jalalirad, Sergio A Gradilone

Oncol Rep· February 2022

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Short-Chain Fatty Acid Butyrate Induces Cilia Formation and Potentiates the Effects of HDAC6 Inhibitors in Cholangiocarcinoma Cells.
Kishor Pant, Seth Richard, Sergio A Gradilone

Front Cell Dev Biol· January 2022

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Histone Deacetylase Sirtuin 1 Promotes Loss of Primary Cilia in Cholangiocarcinoma.
Kishor Pant, Estanislao Peixoto, Seth Richard, Aalekhya Biswas, M Gerard O'Sullivan, Sergio A Gradilone

Hepatology· December 2021

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Synthetic Conjugates of Ursodeoxycholic Acid Inhibit Cystogenesis in Experimental Models of Polycystic Liver Disease.
Francisco J Caballero-Camino, Ivan Rivilla, Elisa Herraez, Oscar Briz, Alvaro Santos-Laso, Sergio A Gradilone

Hepatology· January 2021

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Cholangiocarcinoma 2020: the next horizon in mechanisms and management.
Jesus M Banales, Jose J G Marin, Angela Lamarca, Pedro M Rodrigues, Shahid A Khan, Sergio A Gradilone

Nat Rev Gastroenterol Hepatol· September 2020

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HDAC6-dependent ciliophagy is involved in ciliary loss and cholangiocarcinoma growth in human cells and murine models.
Estanislao Peixoto, Sujeong Jin, Kristen Thelen, Aalekhya Biswas, Seth Richard, Sergio A Gradilone

Am J Physiol Gastrointest Liver Physiol· June 2020

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The primary cilium: Its role as a tumor suppressor organelle.
Estanislao Peixoto, Seth Richard, Kishor Pant, Aalekhya Biswas, Sergio A Gradilone

Biochem Pharmacol· May 2020

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Role of Glucose Metabolism Reprogramming in the Pathogenesis of Cholangiocarcinoma.
Kishor Pant, Seth Richard, Estanislao Peixoto, Sergio A Gradilone

Front Med (Lausanne)· April 2020

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Role of Histone Deacetylases in Carcinogenesis: Potential Role in Cholangiocarcinoma.
Kishor Pant, Estanislao Peixoto, Seth Richard, Sergio A Gradilone

Cells· March 2020

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Characterization of Novel Murine and Human PDAC Cell Models: Identifying the Role of Intestine Specific Homeobox Gene ISX in Hypoxia and Disease Progression.
Arsheed A Ganaie, Aijaz Parray, Tabish Hussain, Ashraf Shabaneh, Anmbreen Jamroze, Sergio A Gradilone

Transl Oncol· August 2019

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The Chemosensory Function of Primary Cilia Regulates Cholangiocyte Migration, Invasion, and Tumor Growth.
Adrian P Mansini, Estanislao Peixoto, Sujeong Jin, Seth Richard, Sergio A Gradilone

Hepatology· April 2019

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