Publications by authors named "Sergio Porte"

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S
Structural and kinetic features of aldehyde dehydrogenase 1A (ALDH1A) subfamily members, cancer stem cell markers active in retinoic acid biosynthesis.
Raquel Pequerul, Javier Vera, Joan Giménez-Dejoz, Isidro Crespo, Joan Coines

Arch Biochem Biophys· March 2020

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Engineering aldo-keto reductase 1B10 to mimic the distinct 1B15 topology and specificity towards inhibitors and substrates, including retinoids and steroids.
Joan Giménez-Dejoz, Susanne Weber, Álvaro Fernández-Pardo, Gabriele Möller, Jerzy Adamski

Chem Biol Interact· July 2019

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Design, synthesis, structure-activity relationships and X-ray structural studies of novel 1-oxopyrimido[4,5-c]quinoline-2-acetic acid derivatives as selective and potent inhibitors of human aldose reductase.
Isidro Crespo, Joan Giménez-Dejoz, Sergio Porté, Alexandra Cousido-Siah, André Mitschler

Eur J Med Chem· May 2018

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Structural basis for the inhibition of AKR1B10 by the C3 brominated TTNPB derivative UVI2008.
Francesc X Ruiz, Isidro Crespo, Susana Álvarez, Sergio Porté, Joan Giménez-Dejoz

Chem Biol Interact· October 2017

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Characterization of AKR1B16, a novel mouse aldo-keto reductase.
Joan Giménez-Dejoz, Susanne Weber, Oleg A Barski, Gabriele Möller, Jerzy Adamski

Chem Biol Interact· October 2017

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Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15: A Novel Human Retinaldehyde Reductase.
Joan Giménez-Dejoz, Michal H Kolář, Francesc X Ruiz, Isidro Crespo, Alexandra Cousido-Siah

PLoS One· May 2016

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Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10.
Francesc X Ruiz, Alexandra Cousido-Siah, Sergio Porté, Marta Domínguez, Isidro Crespo

ChemMedChem· December 2015

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Structural analysis of sulindac as an inhibitor of aldose reductase and AKR1B10.
Alexandra Cousido-Siah, Francesc X Ruiz, Isidro Crespo, Sergio Porté, André Mitschler

Chem Biol Interact· June 2015

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Human prostaglandin reductase 1 (PGR1): Substrate specificity, inhibitor analysis and site-directed mutagenesis.
Julio Mesa, Cristina Alsina, Udo Oppermann, Xavier Parés, Jaume Farrés

Chem Biol Interact· June 2015

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Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design.
Alexandra Cousido-Siah, Francesc X Ruiz, André Mitschler, Sergio Porté, Ángel R de Lera

Acta Crystallogr D Biol Crystallogr· March 2014

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Aldo-keto reductases in retinoid metabolism: search for substrate specificity and inhibitor selectivity.
Sergio Porté, F Xavier Ruiz, Joan Giménez, Iago Molist, Susana Alvarez

Chem Biol Interact· February 2013

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Biocatalytic production of alpha-hydroxy ketones and vicinal diols by yeast and human aldo-keto reductases.
Eduard Calam, Sergio Porté, M Rosario Fernández, Jaume Farrés, Xavier Parés

Chem Biol Interact· February 2013

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Biological role of aldo-keto reductases in retinoic Acid biosynthesis and signaling.
F Xavier Ruiz, Sergio Porté, Xavier Parés, Jaume Farrés

Front Pharmacol· October 2012

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Retinaldehyde is a substrate for human aldo-keto reductases of the 1C subfamily.
F Xavier Ruiz, Sergio Porté, Oriol Gallego, Armando Moro, Albert Ardèvol

Biochem J· December 2011

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Novel alkenal/one reductase activity of yeast NADPH:quinone reductase Zta1p. Prospect of the functional role for the ζ-crystallin family.
Eva Crosas, Sergio Porté, Agrin Moeini, Jaume Farrés, Josep A Biosca

Chem Biol Interact· May 2011

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Kinetic and structural evidence of the alkenal/one reductase specificity of human ζ-crystallin.
Sergio Porté, Agrin Moeini, Irene Reche, Naeem Shafqat, Udo Oppermann

Cell Mol Life Sci· March 2011

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Three-dimensional structure and enzymatic function of proapoptotic human p53-inducible quinone oxidoreductase PIG3.
Sergio Porté, Eva Valencia, Evgenia A Yakovtseva, Emma Borràs, Naeem Shafqat

J Biol Chem· June 2009

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MDR quinone oxidoreductases: the human and yeast zeta-crystallins.
Sergio Porté, Eva Crosas, Evgenia Yakovtseva, Josep A Biosca, Jaume Farrés

Chem Biol Interact· March 2009

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Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids.
Oriol Gallego, Olga V Belyaeva, Sergio Porté, F Xavier Ruiz, Anton V Stetsenko

Biochem J· October 2006

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Expression, localization and potential physiological significance of alcohol dehydrogenase in the gastrointestinal tract.
Julia Vaglenova, Susana E Martínez, Sergio Porté, Gregg Duester, Jaume Farrés

Eur J Biochem· June 2003

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