Publications by authors named "Seth G Thacker"

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Detection of innate immune response modulating impurities (IIRMI) in therapeutic peptides and proteins: Impact of excipients.
Seth G Thacker, Cheng Her, Logan Kelley-Baker, Derek D C Ireland, Mohanraj Manangeeswaran

Front Immunol· September 2022

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BSL2-compliant lethal mouse model of SARS-CoV-2 and variants of concern to evaluate therapeutics targeting the Spike protein.
Mohanraj Manangeeswaran, Derek D C Ireland, Seth G Thacker, Ha-Na Lee, Logan Kelley-Baker

Front Immunol· August 2022

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Effect of Fatty Acid Composition in Polysorbate 80 on the Stability of Therapeutic Protein Formulations.
Melissa A Pegues, Karol Szczepanek, Faruk Sheikh, Seth G Thacker, Baikuntha Aryal

Pharm Res· November 2021

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CpG ODN D35 improves the response to abbreviated low-dose pentavalent antimonial treatment in non-human primate model of cutaneous leishmaniasis.
Seth G Thacker, Ian L McWilliams, Beatrice Bonnet, Lydia Halie, Serge Beaucage

PLoS Negl Trop Dis· February 2020

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Dietary α-cyclodextrin reduces atherosclerosis and modifies gut flora in apolipoprotein E-deficient mice.
Toshihiro Sakurai, Akiko Sakurai, Ye Chen, Boris L Vaisman, Marcelo J Amar, Seth G Thacker

Mol Nutr Food Res· August 2017

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Tofacitinib Ameliorates Murine Lupus and Its Associated Vascular Dysfunction.
Yasuko Furumoto, Carolyne K Smith, Luz Blanco, Wenpu Zhao, Stephen R Brooks, Seth G Thacker

Arthritis Rheumatol· January 2017

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High-density lipoprotein reduces inflammation from cholesterol crystals by inhibiting inflammasome activation.
Seth G Thacker, Abdalrahman Zarzour, Ye Chen, Mustafa S Alcicek, Lita A Freeman

Immunology· November 2016

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Lipoprotein X Causes Renal Disease in LCAT Deficiency.
Alice Ossoli, Edward B Neufeld, Seth G Thacker, Boris Vaisman, Milton Pryor

PLoS One· July 2016

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Elevated interleukin-10: a new cause of dyslipidemia leading to severe HDL deficiency.
Andreas G Moraitis, Lita A Freeman, Robert D Shamburek, Robert Wesley, Wyndham Wilson, Seth G Thacker

J Clin Lipidol· October 2015

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Increased plasma cholesterol esterification by LCAT reduces diet-induced atherosclerosis in SR-BI knockout mice.
Seth G Thacker, Xavier Rousset, Safiya Esmail, Abdalrahman Zarzour, Xueting Jin

J Lipid Res· July 2015

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Synthesis of cholesterol analogues bearing BODIPY fluorophores by Suzuki or Liebeskind-Srogl cross-coupling and evaluation of their potential for visualization of cholesterol pools.
Zheng Liu, Seth G Thacker, Sara Fernandez-Castillejo, Edward B Neufeld, Alan T Remaley

Chembiochem· September 2014

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Type I interferons modulate vascular function, repair, thrombosis, and plaque progression in murine models of lupus and atherosclerosis.
Seth G Thacker, Wenpu Zhao, Carolyne K Smith, Wei Luo, Hui Wang

Arthritis Rheum· September 2012

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Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus.
J Michelle Kahlenberg, Seth G Thacker, Celine C Berthier, Clemens D Cohen, Matthias Kretzler

J Immunol· December 2011

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The detrimental effects of IFN-α on vasculogenesis in lupus are mediated by repression of IL-1 pathways: potential role in atherogenesis and renal vascular rarefaction.
Seth G Thacker, Celine C Berthier, Deborah Mattinzoli, Maria Pia Rastaldi, Matthias Kretzler

J Immunol· October 2010

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A distinct subset of proinflammatory neutrophils isolated from patients with systemic lupus erythematosus induces vascular damage and synthesizes type I IFNs.
Michael F Denny, Srilakshmi Yalavarthi, Wenpu Zhao, Seth G Thacker, Marc Anderson

J Immunol· March 2010

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The peroxisome proliferator-activated receptor gamma agonist pioglitazone improves cardiometabolic risk and renal inflammation in murine lupus.
Wenpu Zhao, Seth G Thacker, Jeffrey B Hodgin, Hongyu Zhang, Jeffrey H Wang

J Immunol· August 2009

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Interactions of T cells with fibroblast-like synoviocytes: role of the B7 family costimulatory ligand B7-H3.
Chinh N Tran, Seth G Thacker, Deanna M Louie, Jennifer Oliver, Peter T White

J Immunol· March 2008

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