Publications by authors named "Seth Lederman"

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Proteinuria Remains a Significant Hurdle to Successful Pig Kidney Xenotransplantation Despite an Effective Immunosuppressive Regimen.
Kohei Kinoshita, Akihiro Maenaka, Maho Terashita, Ivy A Rosales, Yuji Hidaka, Seth Lederman

Transplantation· January 2026

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A CXCR4 partial agonist improves immunotherapy by targeting immunosuppressive neutrophils and cancer-driven granulopoiesis.
Jin Qian, Chenkai Ma, Quin T Waterbury, Xiaofei Zhi, Christine S Moon, Seth Lederman

Cancer Cell· August 2025

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Pain Relief by Targeting Nonrestorative Sleep in Fibromyalgia: A Phase 3 Randomized Trial of Bedtime Sublingual Cyclobenzaprine.
Seth Lederman, Lesley M Arnold, Ben Vaughn, Jean M Engels, Mary Kelley

Pain Med· July 2025

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Enhanced Costimulation Blockade With αCD154, αCD2, and αCD28 to Promote Heart Allograft Tolerance in Nonhuman Primates.
Ryan Chaban, Ikechukwu Ileka, Kohei Kinoshita, Gannon McGrath, Zahra Habibabady, Seth Lederman

Transplantation· June 2025

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Extended survival of 9- and 10-gene-edited pig heart xenografts with ischemia minimization and CD154 costimulation blockade-based immunosuppression.
Ryan Chaban, Ikechukwu Ileka, Gannon McGrath, Kohei Kinoshita, Zahra Habibabady, Seth Lederman

J Heart Lung Transplant· December 2024

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Recombinant chimeric horsepox virus (TNX-801) is attenuated relative to vaccinia virus strains in both and models.
Stephanie V Trefry, Mayanka Awasthi, Christy N Raney, Amy L Cregger, Chase A Gonzales, Seth Lederman

mSphere· December 2024

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A CXCR4 partial agonist improves immunotherapy by targeting polymorphonuclear myeloid-derived suppressor cells and cancer-driven granulopoiesis.
Jin Qian, Chenkai Ma, Quin T Waterbury, Xiaofei Zhi, Christine S Moon, Seth Lederman

bioRxiv· October 2024

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High-Throughput Screening Assay for Convalescent Sera in COVID-19: Efficacy, Donor Selection, and Variant Neutralization.
Krishna P Kota, Ilya Trakht, Gavreel Kalantarov, David Ordonez, Jiayi Wei, Seth Lederman

Microorganisms· July 2024

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Chronic overlapping pain conditions increase the risk of long COVID features, regardless of acute COVID status.
Rachel S Bergmans, Daniel J Clauw, Candace Flint, Herb Harris, Seth Lederman

Pain· May 2024

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A phase 3, randomized, placebo-controlled, trial to evaluate the efficacy and safety of bedtime sublingual cyclobenzaprine (TNX-102 SL) in military-related posttraumatic stress disorder.
Megan E Parmenter, Seth Lederman, Frank W Weathers, Lori L Davis, Benjamin Vaughn

Psychiatry Res· April 2024

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Novel factors potentially initiating acute antibody-mediated rejection in pig kidney xenografts despite an efficient immunosuppressive regimen.
Kohei Kinoshita, Akihiro Maenaka, Ivy A Rosales, Ahmad Karadagi, Toshihide Tomosugi, Seth Lederman

Xenotransplantation· April 2024

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Efficacy and Safety of Sublingual Cyclobenzaprine for the Treatment of Fibromyalgia: Results From a Randomized, Double-Blind, Placebo-Controlled Trial.
Seth Lederman, Lesley M Arnold, Ben Vaughn, Mary Kelley, Gregory M Sullivan

Arthritis Care Res (Hoboken)· November 2023

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Immunogenicity and Efficacy of TNX-1800, A Live Virus Recombinant Poxvirus Vaccine Candidate, against SARS-CoV-2 Challenge in Nonhuman Primates.
Mayanka Awasthi, Anthony Macaluso, Dawn Myscofski, Jon Prigge, Fusataka Koide, Seth Lederman

Vaccines (Basel)· November 2023

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Immunogenicity and Tolerability of a SARS-CoV-2 TNX-1800, a Live Recombinant Poxvirus Vaccine Candidate, in Syrian Hamsters and New Zealand White Rabbits.
Mayanka Awasthi, Anthony Macaluso, Scott J Goebel, Erin Luea, Ryan S Noyce, Seth Lederman

Viruses· October 2023

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TNX-1500, a crystallizable fragment-modified anti-CD154 antibody, prolongs nonhuman primate renal allograft survival.
Grace Lassiter, Ryo Otsuka, Takayuki Hirose, Ivy Rosales, Ahmad Karadagi, Seth Lederman

Am J Transplant· August 2023

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TNX-1500, a crystallizable fragment-modified anti-CD154 antibody, prolongs nonhuman primate cardiac allograft survival.
Shuhei Miura, Zahra A Habibabady, Franziska Pollok, Madelyn Ma, Ivy A Rosales, Seth Lederman

Am J Transplant· August 2023

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Development of a rapid image-based high-content imaging screening assay to evaluate therapeutic antibodies against the monkeypox virus.
Krishna P Kota, Natasza E Ziółkowska, Jiayi Wei, Junzhong Peng, David Ordonez, Seth Lederman

Antiviral Res· February 2023

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Single Dose of Recombinant Chimeric Horsepox Virus (TNX-801) Vaccination Protects Macaques from Lethal Monkeypox Challenge.
Ryan S Noyce, Landon W Westfall, Siobhan Fogarty, Karen Gilbert, Onesmo Mpanju, Seth Lederman

Viruses· January 2023

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Randomization tests in clinical trials with multiple imputation for handling missing data.
Anastasia Ivanova, Seth Lederman, Philip B Stark, Gregory Sullivan, Ben Vaughn

J Biopharm Stat· May 2022

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Randomized clinical trial of bedtime sublingual cyclobenzaprine (TNX-102 SL) in military-related PTSD and the role of sleep quality in treatment response.
Gregory M Sullivan, R Michael Gendreau, Judith Gendreau, Perry Peters, Ashild Peters, Seth Lederman

Psychiatry Res· July 2021

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Predictors of Response to Prolonged Exposure, Sertraline, and Their Combination for the Treatment of Military PTSD.
Sheila A M Rauch, H Myra Kim, Seth Lederman, Gregory Sullivan, Ron Acierno

J Clin Psychiatry· June 2021

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Early smallpox vaccine manufacturing in the United States: Introduction of the "animal vaccine" in 1870, establishment of "vaccine farms", and the beginnings of the vaccine industry.
José Esparza, Seth Lederman, Andreas Nitsche, Clarissa R Damaso

Vaccine· June 2020

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Construction of an infectious horsepox virus vaccine from chemically synthesized DNA fragments.
Ryan S Noyce, Seth Lederman, David H Evans

PLoS One· February 2018

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Effects of bedtime very low dose cyclobenzaprine on symptoms and sleep physiology in patients with fibromyalgia syndrome: a double-blind randomized placebo-controlled study.
Harvey Moldofsky, Herbert W Harris, W Tad Archambault, Terence Kwong, Seth Lederman

J Rheumatol· December 2011

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