Publications by authors named "Seth Parker"

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Protocol for measuring D-amino acid transport in mammalian cells using a fluorescent biosensor.
Danisha Johal, Keeley G Hewton, Sadie J Gale, Amritpal S Johal, Seth J Parker

STAR Protoc· September 2025

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Metabolomics analysis of SNAT2-deficient cells: Implications for the discovery of selective small-molecule inhibitors of an amino acid transporter.
Jessica C Koe, Yuxi C Zhong, Kiana Pashaoskooie, Gregory J Kaczorowski, Maria L Garcia, Seth J Parker

J Biol Chem· September 2025

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Proteomics and personalized PDX models identify treatment for a progressive malignancy within an actionable timeframe.
Georgina D Barnabas, Tariq A Bhat, Verena Goebeler, Pascal Leclair, Nadine Azzam, Seth J Parker

EMBO Mol Med· April 2025

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Restricting lysine normalizes toxic catabolites associated with ALDH7A1 deficiency in cells and mice.
Amritpal S Johal, Hilal H Al-Shekaili, Muna Abedrabbo, Abisola Z Kehinde, Morgan Towriss, Seth J Parker

Cell Rep· December 2024

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Pancreatic cancer tumor organoids exhibit subtype-specific differences in metabolic profiles.
Hassan A Ali, Joanna M Karasinska, James T Topham, Danisha Johal, Steve Kalloger, Seth J Parker

Cancer Metab· October 2024

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On the spinal venous sinus of Alligator mississippiensis.
Seth Parker, Michael Cramberg, Anchal Scott, Stephanie Sopko, Annelise Swords

Anat Rec (Hoboken)· September 2024

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Editorial overview: Tumor-stroma crosstalk: Shaping and characterizing the metabolic microenvironment of tumors.
Seth Parker, Thekla Cordes

Curr Opin Biotechnol· June 2024

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The presence of a foramen of Luschka in the American alligator (Alligator mississippiensis) and the continuity of the intraventricular and subdural spaces.
Ethan Taylor, Michael Cramberg, Seth Parker, Anchal Scott, Stephanie Sopko

J Anat· March 2024

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The Crocodylian proatlas functions to redistribute venous blood and cerebrospinal fluid.
Annelise Swords, Michael Cramberg, Seth Parker, Anchal Scott, Stephanie Sopko

J Morphol· March 2024

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The posttranslational regulation of amino acid transporters is critical for their function in the tumor microenvironment.
Jessica C Koe, Seth J Parker

Curr Opin Biotechnol· February 2024

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Targeting pancreatic cancer metabolic dependencies through glutamine antagonism.
Joel Encarnación-Rosado, Albert S W Sohn, Douglas E Biancur, Elaine Y Lin, Victoria Osorio-Vasquez, Seth J Parker

Nat Cancer· January 2024

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A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor Cells.
Geetha Venkateswaran, Paul C McDonald, Shawn C Chafe, Wells S Brown, Zachary J Gerbec, Seth J Parker

Mol Cancer Ther· October 2023

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A Peptidisc-Based Survey of the Plasma Membrane Proteome of a Mammalian Cell.
Zhiyu Zhao, Arshdeep Khurana, Frank Antony, John W Young, Keeley G Hewton, Seth J Parker

Mol Cell Proteomics· August 2023

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Transsulfuration, minor player or crucial for cysteine homeostasis in cancer.
Hai-Feng Zhang, Ramon I Klein Geltink, Seth J Parker, Poul H Sorensen

Trends Cell Biol· September 2022

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SLC4A7 and mTORC1 raise nucleotide synthesis with bicarbonate.
Jessica C Koe, Keeley G Hewton, Seth J Parker

Mol Cell· September 2022

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No Back-up Plan: Loss of Isozyme Diversity as a Promising Therapeutic Strategy for Cancer.
Abisola Z Kehinde, Seth J Parker

Cancer Res· May 2022

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Metabolic reprogramming of tumor-associated macrophages by collagen turnover promotes fibrosis in pancreatic cancer.
Madeleine M LaRue, Seth Parker, Joseph Puccini, Michael Cammer, Alec C Kimmelman

Proc Natl Acad Sci U S A· April 2022

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Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma.
Hai-Feng Zhang, Christopher S Hughes, Wei Li, Jian-Zhong He, Didier Surdez, Seth J Parker

Cancer Discov· November 2021

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Spontaneous hydrolysis and spurious metabolic properties of α-ketoglutarate esters.
Seth J Parker, Joel Encarnación-Rosado, Kate E R Hollinshead, David M Hollinshead, Leonard J Ash

Nat Commun· August 2021

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Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11.
Subhadip Mukhopadhyay, Douglas E Biancur, Seth J Parker, Keisuke Yamamoto, Robert S Banh

Proc Natl Acad Sci U S A· February 2021

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Transporters at the Interface between Cytosolic and Mitochondrial Amino Acid Metabolism.
Keeley G Hewton, Amritpal S Johal, Seth J Parker

Metabolites· February 2021

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Respiratory Supercomplexes Promote Mitochondrial Efficiency and Growth in Severely Hypoxic Pancreatic Cancer.
Kate E R Hollinshead, Seth J Parker, Vinay V Eapen, Joel Encarnacion-Rosado, Albert Sohn

Cell Rep· October 2020

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Disruption of redox homeostasis for combinatorial drug efficacy in tumors as revealed by metabolic connectivity profiling.
Daniela Gaglio, Marcella Bonanomi, Silvia Valtorta, Rohit Bharat, Marilena Ripamonti, Seth J Parker

Cancer Metab· September 2020

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Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I.
Keisuke Yamamoto, Anthony Venida, Julian Yano, Douglas E Biancur, Miwako Kakiuchi, Seth J Parker

Nature· May 2020

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