Publications by authors named "Seth Sharp"

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Development and Validation of a Type 1 Diabetes Multi-Ancestry Polygenic Score.
Aaron J Deutsch, Andrew S Bell, Dominika A Michalek, Adam B Burkholder, Stella Nam, Seth A Sharp

Diabetes· January 2026

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Diabetes mellitus polygenic risk scores: heterogeneity and clinical translation.
Hector I Ortega, Miriam S Udler, Anna L Gloyn, Seth A Sharp

Nat Rev Endocrinol· September 2025

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Heterogeneous endocrine cell composition defines human islet functional phenotypes.
Carmella Evans-Molina, Yasminye D Pettway, Diane C Saunders, Seth A Sharp, Thomas Sr Bate

bioRxiv· August 2025

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Prediction of metabolic subphenotypes of type 2 diabetes via continuous glucose monitoring and machine learning.
Ahmed A Metwally, Dalia Perelman, Heyjun Park, Yue Wu, Alokkumar Jha, Seth Sharp

Nat Biomed Eng· August 2025

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Standardized Measurement of Type 1 Diabetes Polygenic Risk Across Multiancestry Population Cohorts.
Amber M Luckett, Richard A Oram, Aaron J Deutsch, Hector I Ortega, Diane P Fraser, Seth A Sharp

Diabetes Care· June 2025

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Development and Validation of a Type 1 Diabetes Multi-Ancestry Polygenic Score.
Aaron J Deutsch, Andrew S Bell, Dominika A Michalek, Adam B Burkholder, Stella Nam, Seth A Sharp

medRxiv· June 2025

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HumanIslets.com: Improving accessibility, integration, and usability of human research islet data.
Jessica D Ewald, Yao Lu, Cara E Ellis, Jessica Worton, Jelena Kolic, Seth A Sharp

Cell Metab· January 2025

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Standardized Measurement of Type 1 Diabetes Polygenic Risk Across Multi-Ancestry Population Cohorts.
Amber M Luckett, Richard A Oram, Aaron J Deutsch, Hector I Ortega, Diane P Fraser, Seth A Sharp

medRxiv· January 2025

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Clinical Prediction Models Combining Routine Clinical Measures Have High Accuracy in Identifying Youth-Onset Type 2 Diabetes Defined by Maintained Endogenous Insulin Secretion: The SEARCH for Diabetes in Youth Study.
Angus G Jones, Beverley M Shields, Richard A Oram, Dana M Dabelea, William A Hagopian, Seth A Sharp

Diabetes Care· December 2024

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Type 1 diabetes genetic risk score variation across ancestries using whole genome sequencing and array-based approaches.
Ankit M Arni, Diane P Fraser, Seth A Sharp, Richard A Oram, Matthew B Johnson

Sci Rep· December 2024

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Predicting Type 2 Diabetes Metabolic Phenotypes Using Continuous Glucose Monitoring and a Machine Learning Framework.
Ahmed A Metwally, Dalia Perelman, Heyjun Park, Yue Wu, Alokkumar Jha, Seth Sharp

medRxiv· September 2024

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CD39 delineates chimeric antigen receptor regulatory T cell subsets with distinct cytotoxic & regulatory functions against human islets.
Xiangni Wu, Pin-I Chen, Robert L Whitener, Matthew S MacDougall, Vy M N Coykendall, Seth A Sharp

Front Immunol· July 2024

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Type 1 Diabetes Genetic Risk in 109,954 Veterans With Adult-Onset Diabetes: The Million Veteran Program (MVP).
Peter K Yang, Sandra L Jackson, Brian R Charest, Yiling J Cheng, Yan V Sun, Seth A Sharp

Diabetes Care· June 2024

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HumanIslets: An integrated platform for human islet data access and analysis.
Jessica D Ewald, Yao Lu, Cara E Ellis, Jessica Worton, Jelena Kolic, Seth A Sharp

bioRxiv· June 2024

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Corrigendum to 'Identifying type 1 and 2 diabetes in research datasets where classification biomarkers are unavailable: assessing the accuracy of published approaches' [Journal of Clinical Epidemiology (2023) 34-44].
Nicholas J Thomas, Andrew McGovern, Katherine G Young, Seth A Sharp, Michael N Weedon

J Clin Epidemiol· July 2023

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Identifying type 1 and 2 diabetes in research datasets where classification biomarkers are unavailable: assessing the accuracy of published approaches.
Nicholas J Thomas, Andrew McGovern, Katherine G Young, Seth A Sharp, Michael N Weedon

J Clin Epidemiol· January 2023

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Utility of Diabetes Type-Specific Genetic Risk Scores for the Classification of Diabetes Type Among Multiethnic Youth.
Richard A Oram, Seth A Sharp, Catherine Pihoker, Lauric Ferrat, Giuseppina Imperatore

Diabetes Care· May 2022

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Author Correction: A combined risk score enhances prediction of type 1 diabetes among susceptible children.
Lauric A Ferrat, Kendra Vehik, Seth A Sharp, Åke Lernmark, Marian J Rewers

Nat Med· March 2022

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Correction to: DR15-DQ6 remains dominantly protective against type 1 diabetes throughout the first five decades of life.
Nicholas J Thomas, John M Dennis, Seth A Sharp, Akaal Kaur, Shivani Misra

Diabetologia· January 2022

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Estimating disease prevalence in large datasets using genetic risk scores.
Benjamin D Evans, Piotr Słowiński, Andrew T Hattersley, Samuel E Jones, Seth Sharp

Nat Commun· November 2021

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DR15-DQ6 remains dominantly protective against type 1 diabetes throughout the first five decades of life.
Nicholas J Thomas, John M Dennis, Seth A Sharp, Akaal Kaur, Shivani Misra

Diabetologia· October 2021

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A single nucleotide polymorphism genetic risk score to aid diagnosis of coeliac disease: a pilot study in clinical care.
Seth A Sharp, Samuel E Jones, Robert A Kimmitt, Michael N Weedon, Anne M Halpin

Aliment Pharmacol Ther· October 2020

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IgA Nephropathy Genetic Risk Score to Estimate the Prevalence of IgA Nephropathy in UK Biobank.
Kittiya Sukcharoen, Seth A Sharp, Nicholas J Thomas, Robert A Kimmitt, Jamie Harrison

Kidney Int Rep· October 2020

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A combined risk score enhances prediction of type 1 diabetes among susceptible children.
Lauric A Ferrat, Kendra Vehik, Seth A Sharp, Åke Lernmark, Marian J Rewers

Nat Med· August 2020

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Type 1 diabetes genetic risk score is discriminative of diabetes in non-Europeans: evidence from a study in India.
James W Harrison, Divya Sri Priyanka Tallapragada, Alma Baptist, Seth A Sharp, Seema Bhaskar

Sci Rep· June 2020

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