Publications by authors named "Shad Smith"

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Preclinical perspectives on disorders of the temporomandibular joint: Tracing the past, navigating the present, and shaping the future.
John K Neubert, Kyle Allen, Tamara Alliston, Alejandro J Almarza, Kyriacos A Athanasiou, Shad B Smith

J Pain· November 2025

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Vestibulodynia presentation is differentiated by the presence of additional chronic primary pain conditions.
Chloe Shudt, Shad Smith, Andrey Bortsov, Kayla Parr, Sheila Gaynor

J Pain· August 2025

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Clinical and biobehavioral phenotypic assessments and data harmonization for the RE-JOIN research consortium: Recommendations for common data element selection.
Yenisel Cruz-Almeida, Bella Mehta, Nele A Haelterman, Alisa J Johnson, Chloe Heiting, Shad B Smith

Neurobiol Pain· August 2024

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Whole-genome methylation profiling reveals regions associated with painful temporomandibular disorders and active recovery processes.
Xiang Ao, Marc Parisien, Roger B Fillingim, Richard Ohrbach, Gary D Slade, Shad B Smith

Pain· May 2024

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A mouse model of chronic primary pain that integrates clinically relevant genetic vulnerability, stress, and minor injury.
Yaomin Wang, Shin Hyung Kim, Marguerita E Klein, Jiegen Chen, Elizabeth Gu, Shad Smith

Sci Transl Med· April 2024

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The Chronic Overlapping Pain Condition Screener.
Andrew Schrepf, William Maixner, Roger Fillingim, Christin Veasley, Richard Ohrbach, Shad Smith

J Pain· January 2024

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Applying the Rapid OPPERA Algorithm to Predict Persistent Pain Outcomes Among a Cohort of Women Undergoing Breast Cancer Surgery.
Jenna M Wilson, Carin A Colebaugh, K Mikayla Flowers, Demario Overstreet, Robert R Edwards, Shad B Smith

J Pain· December 2022

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Phenotypic profile clustering pragmatically identifies diagnostically and mechanistically informative subgroups of chronic pain patients.
Sheila M Gaynor, Andrey Bortsov, Eric Bair, Roger B Fillingim, Joel D Greenspan, Shad B Smith

Pain· May 2021

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Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry.
Mariaelisa Graff, Anne E Justice, Kristin L Young, Eirini Marouli, Xinruo Zhang, Jennifer A Smith, Shad Smith

Am J Hum Genet· April 2021

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Multi-ethnic GWAS and meta-analysis of sleep quality identify MPP6 as a novel gene that functions in sleep center neurons.
Samar Khoury, Qiao-Ping Wang, Marc Parisien, Pavel Gris, Andrey V Bortsov, Shad B Smith

Sleep· March 2021

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A genetic polymorphism that is associated with mitochondrial energy metabolism increases risk of fibromyalgia.
Miranda A L van Tilburg, Marc Parisien, Richard G Boles, Gillian L Drury, Julian Smith-Voudouris, Shad B Smith

Pain· December 2020

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Reversion mutation of cDNA CA8-204 minigene construct produces a truncated functional peptide that regulates calcium release in vitro and produces profound analgesia in vivo.
Udita Upadhyay, Gerald Z Zhuang, Luda Diatchenko, Marc Parisien, Yuan Kang, Shad B Smith

Mamm Genome· December 2020

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A functional substitution in the L-aromatic amino acid decarboxylase enzyme worsens somatic symptoms via a serotonergic pathway.
Samar Khoury, Marjo H Piltonen, Anh-Tien Ton, Tiffany Cole, Alexander Samoshkin, Shad B Smith

Ann Neurol· August 2019

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Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL.
Udita Upadhyay, Gerald Z Zhuang, Luda Diatchenko, Marc Parisien, Yuan Kang, Shad B Smith

PLoS Genet· June 2019

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Genome-wide association reveals contribution of MRAS to painful temporomandibular disorder in males.
Shad B Smith, Marc Parisien, Eric Bair, Inna Belfer, Anne-Julie Chabot-Doré

Pain· March 2019

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Disentangling the genetics of lean mass.
David Karasik, M Carola Zillikens, Yi-Hsiang Hsu, Ali Aghdassi, Kristina Akesson, Albert V Smith, Shad B Smith

Am J Clin Nutr· February 2019

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Evidence that Dry Eye Represents a Chronic Overlapping Pain Condition.
Alexandra E Levitt, Anat Galor, Aneesa R Chowdhury, Elizabeth R Felix, Constantinos D Sarantopoulos, Shad B Smith

Mol Pain· September 2018

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Human carbonic anhydrase-8 AAV8 gene therapy inhibits nerve growth factor signaling producing prolonged analgesia and anti-hyperalgesia in mice.
Gerald Z Zhuang, Udita Upadhyay, Xiaoying Tong, Yuan Kang, Diana M Erasso, Shad B Smith

Gene Ther· July 2018

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Genomics of Cardiovascular Measures of Autonomic Tone.
Martin I Sigurdsson, Nathan H Waldron, Andrey V Bortsov, Shad B Smith, William Maixner

J Cardiovasc Pharmacol· March 2018

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Impact of human CA8 on thermal antinociception in relation to morphine equivalence in mice.
Eugene S Fu, Diana M Erasso, Gerald Z Zhuang, Udita Upadhyay, Mehtap Ozdemir, Shad B Smith

Neuroreport· December 2017

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Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
M Carola Zillikens, Serkalem Demissie, Yi-Hsiang Hsu, Laura M Yerges-Armstrong, Wen-Chi Chou, Albert V Smith, Shad Smith

Nat Commun· November 2017

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Car8 dorsal root ganglion expression and genetic regulation of analgesic responses are associated with a cis-eQTL in mice.
Roy C Levitt, Gerald Y Zhuang, Yuan Kang, Diana M Erasso, Udita Upadhyay, Shad B Smith

Mamm Genome· October 2017

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Epiregulin and EGFR interactions are involved in pain processing.
Loren J Martin, Shad B Smith, Arkady Khoutorsky, Claire A Magnussen, Alexander Samoshkin

J Clin Invest· September 2017

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Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
M Carola Zillikens, Serkalem Demissie, Yi-Hsiang Hsu, Laura M Yerges-Armstrong, Wen-Chi Chou, Albert V Smith, Shad Smith

Nat Commun· July 2017

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Effect of Human Genetic Variability on Gene Expression in Dorsal Root Ganglia and Association with Pain Phenotypes.
Marc Parisien, Samar Khoury, Anne-Julie Chabot-Doré, Susana G Sotocinal, Gary D Slade, Shad B Smith

Cell Rep· May 2017

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