Publications by authors named "Shaker Mohammed"

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Metabolism at the core of melanoma: From bioenergetics to immune escape and beyond.
Chou-Yi Hsu, Yasmeen Kateb Ahmed, Shaker Mohammed, Mohammad A Alghamdi, Hasan S Al-Ghamdi, Jaafaru Sani Mohammed, Mohammed Abed Jawad

Semin Oncol· December 2025

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SARS-CoV-2 infection in hiPSC-derived neurons is cathepsin-dependent and causes differential accumulation of HIF1ɑ and phosphorylated tau.
Pinja Kettunen, Janika Ruuska, Tania Quirin, Ravi Ojha, Saber H Saber, Mohammed R Shaker

Mol Ther Nucleic Acids· December 2025

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Enhanced U-Net-Based Deep Learning Model for Automated Segmentation of Organoid Images.
Maath Alani, Hamid A Jalab, Selin Pars, Bahaa Al-Mhanawi, Rowaida Z Taha, Mohammed R Shaker

Bioengineering (Basel)· November 2025

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Valproic acid-induced teratogenicity is driven by senescence and prevented by Rapamycin in human spinal cord and animal models.
Giovanni Pietrogrande, Mohammed R Shaker, Sarah J Stednitz, Farhad Soheilmoghaddam, Julio Aguado

Mol Psychiatry· March 2025

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Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity.
Mohammed R Shaker, Salam Salloum-Asfar, Rowaida Z Taha, Ibrahim Javed, Ernst J Wolvetang

Mol Brain· March 2025

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A Roadmap for Selecting and Utilizing Optimal Features in scRNA Sequencing Data Analysis for Stem Cell Research: A Comprehensive Review.
Maath Alani, Hamza Altarturih, Selin Pars, Bahaa Al-Mhanawi, Ernst J Wolvetang, Mohammed R Shaker

Int J Stem Cells· November 2024

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Choroid plexus defects in Down syndrome brain organoids enhance neurotropism of SARS-CoV-2.
Mohammed R Shaker, Andrii Slonchak, Bahaa Al-Mhanawi, Sean D Morrison, Julian D J Sng

Sci Adv· June 2024

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Protocol for generating embedding-free brain organoids enriched with oligodendrocytes.
Bahaa Al-Mhanawi, Marta Boira Marti, Sean D Morrison, Pallavi Gupta, Maath Alani, Mohammed R Shaker

STAR Protoc· December 2023

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Transcriptional Signature of Valproic Acid-Induced Neural Tube Defects in Human Spinal Cord Organoids.
Ju-Hyun Lee, Mohammed R Shaker, Si-Hyung Park, Woong Sun

Int J Stem Cells· November 2023

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Robust and Highly Reproducible Generation of Cortical Brain Organoids for Modelling Brain Neuronal Senescence In Vitro.
Mohammed R Shaker, Zoe L Hunter, Ernst J Wolvetang

J Vis Exp· May 2022

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Human induced pluripotent stem cells generated from epilepsy patients for use as in vitro models for drug screening.
Zoe L Hunter, Hannah C Leeson, Mohammed R Shaker, Ernst J Wolvetang, Lata Vadlamudi

Stem Cell Res· April 2022

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Production of human spinal-cord organoids recapitulating neural-tube morphogenesis.
Ju-Hyun Lee, Hyogeun Shin, Mohammed R Shaker, Hyun Jung Kim, Si-Hyung Park

Nat Biomed Eng· April 2022

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Neural Epidermal Growth Factor-Like Like Protein 2 Is Expressed in Human Oligodendroglial Cell Types.
Mohammed R Shaker, Amna Kahtan, Renuka Prasad, Ju-Hyun Lee, Giovanni Pietrogrande

Front Cell Dev Biol· February 2022

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Effectiveness of combined therapy radiofrequency ablation/transarterial chemoembolization versus transarterial chemoembolization/radiofrequency ablation on management of hepatocellular carcinoma.
Ahmed Kaml El Dorry, Mohammed Kamal Shaker, Nevien Fouad El-Fouly, Ahmed Hussien, Runia Fouad El-Folly

Eur J Gastroenterol Hepatol· December 2021

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Spatiotemporal contribution of neuromesodermal progenitor-derived neural cells in the elongation of developing mouse spinal cord.
Mohammed R Shaker, Ju-Hyun Lee, Kyung Hyun Kim, Saeli Ban, Veronica Jihyun Kim

Life Sci· October 2021

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Hypermethylation of Mest promoter causes aberrant Wnt signaling in patients with Alzheimer's disease.
Renuka Prasad, Hwajin Jung, Anderson Tan, Yonghee Song, Sungho Moon, Mohammed R Shaker

Sci Rep· October 2021

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Generation of induced pluripotent stem cell lines from peripheral blood mononuclear cells of three drug resistant and three drug responsive epilepsy patients.
Zoe L Hunter, Hannah C Leeson, Mohammed R Shaker, Ernst J Wolvetang, Lata Vadlamudi

Stem Cell Res· October 2021

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Inhibition of the cGAS-STING pathway ameliorates the premature senescence hallmarks of Ataxia-Telangiectasia brain organoids.
Julio Aguado, Harman K Chaggar, Cecilia Gómez-Inclán, Mohammed R Shaker, Hannah C Leeson

Aging Cell· September 2021

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Klotho inhibits neuronal senescence in human brain organoids.
Mohammed R Shaker, Julio Aguado, Harman Kaur Chaggar, Ernst J Wolvetang

NPJ Aging Mech Dis· August 2021

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Embryonal Neuromesodermal Progenitors for Caudal Central Nervous System and Tissue Development.
Mohammed R Shaker, Ju-Hyun Lee, Woong Sun

J Korean Neurosurg Soc· May 2021

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Rapid and Efficient Generation of Myelinating Human Oligodendrocytes in Organoids.
Mohammed R Shaker, Giovanni Pietrogrande, Sally Martin, Ju-Hyun Lee, Woong Sun

Front Cell Neurosci· March 2021

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Anteroposterior Wnt-RA Gradient Defines Adhesion and Migration Properties of Neural Progenitors in Developing Spinal Cord.
Mohammed R Shaker, Ju-Hyun Lee, Si-Hyung Park, Joo Yeon Kim, Gi Hoon Son

Stem Cell Reports· October 2020

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Evaluation of Golgi Protein 73 (GP73) as a Potential Biomarkers for Hepatocellular Carcinoma.
Mohammed K Shaker, Fadia M Attia, Adel A Hassan, Mahmoud M Shedid, Mohammed A Aboelmagd

Clin Lab· August 2020

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NeuroCore formation during differentiation of neurospheres of mouse embryonic neural stem cells.
Ju-Hyun Lee, Mohammed R Shaker, Eunsoo Lee, Boram Lee, Woong Sun

Stem Cell Res· March 2020

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High-Performance Acellular Tissue Scaffold Combined with Hydrogel Polymers for Regenerative Medicine.
Eunsoo Lee, Hyun Jung Kim, Mohammed R Shaker, Jae Ryun Ryu, Min Seok Ham

ACS Biomater Sci Eng· July 2019

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