Publications by authors named "Shakir D AlSharari"

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Nicotine reward in the conditioned place preference test across a panel of male inbred mice and F1 crosses: genetic influence and correlation with variation in nicotine antinociception.
Belle Buzzi, Shakir D AlSharari, Julian Vaughn, Erin Kalck, Walker D Rogers

Psychopharmacology (Berl)· October 2025

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Selective Effects of Acutely Administered N-Acetyl-Cysteine in Rodent Models of Nicotine-Conditioned Behaviours.
Kelsey Stoddart, Michael Davies, Jamie Oughton, Emma Malcolm, Shakir D AlSharari

Addict Biol· September 2025

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Nicotine Attenuates Molecular Signalings in the BTBR T Itpr3/J Mouse Model of Autism.
Shakir D AlSharari, Hafiz M Mahmood, Abdullah F Alasmari, Hesham M AlDhalaan, Fawaz Alasmari

Mol Neurobiol· August 2025

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Semaglutide ameliorated autism-like behaviors and DNA repair efficiency in male BTBR mice by recovering DNA repair gene expression.
Marwa H Hussein, Alaa A Alameen, Mushtaq A Ansari, Shakir D AlSharari, Sheikh F Ahmad

Prog Neuropsychopharmacol Biol Psychiatry· December 2024

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New Pharmacological Insight into Etanercept and Pregabalin in Allodynia and Nociception: Behavioral Studies in a Murine Neuropathic Pain Model.
Loulwah Alothman, Emad Alhadlaq, Asma Alhussain, Alwaleed Alabdulkarim, Youssef Sari, Shakir D AlSharari

Brain Sci· November 2024

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Activation of α7 nicotinic receptors attenuated hyperalgesia and anxiety induced by palatable obesogenic diet withdrawal.
Shakir D AlSharari, Alaa A Alameen, Fawzeyah S Aldafiri, Yousif S Ali, Musaad A Alshammari

J Pharmacol Sci· October 2024

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The potential effect of α7 nicotinic receptors modulation on palatable food-induced dependence-like behaviors.
Alaa A Alameen, Shakir D AlSharari, Musaad A Alshammari, M I Damaj, Y Sari

Saudi Pharm J· August 2024

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Neuroinflammation and Neurometabolomic Profiling in Fentanyl Overdose Mouse Model Treated with Novel β-Lactam, MC-100093, and Ceftriaxone.
Mohammed S Alasmari, Fawaz Alasmari, Shakir D Alsharari, Abdullah F Alasmari, Nemat Ali

Toxics· August 2024

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Effects of novel beta-lactam, MC-100093, and ceftriaxone on astrocytic glutamate transporters and neuroinflammatory factors in nucleus accumbens of C57BL/6 mice exposed to escalated doses of morphine.
Youssef Sari, Ghadeer M S Swiss, Fatin A Alrashedi, Kholoud A Baeshen, Sultan A Alshammari, Shakir D Alsharari

Saudi Pharm J· July 2024

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Increased Permeability of the Blood-Brain Barrier in a Diabetic Mouse Model ( Mice).
Musaad A Alshammari, Abdulaziz O Alshehri, Faleh Alqahtani, Mohammad R Khan, Muhammed A Bakhrebah, Shakir D Alsharari

Int J Mol Sci· July 2024

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Nelotanserin, a selective 5-HT2A receptor inverse agonist, attenuates aspects of nicotine withdrawal but not reward in mice.
Belle Buzzi, Shakir D AlSharari, David M Walentiny, M Imad Damaj

Behav Brain Res· June 2024

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Therapeutic benefits of quercetin in traumatic brain injury model exposed to cigarette smoke.
Faleh Alqahtani, Yousif S Mohamed Ali, Mohammed M Almutairi, Abdullah F Alotaibi, Imran Imran, Shakir D AlSharari

Saudi Pharm J· January 2024

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Investigating Behavioral and Neuronal Changes in Adolescent Mice Following Prenatal Exposure to Electronic Cigarette (E-Cigarette) Vapor Containing Nicotine.
Alaa AlHarthi, Fawaz Alasmari, Shakir D AlSharari, Nouf M Alrasheed, Musaad A Alshammari

Brain Sci· October 2023

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Clavulanic Acid Improves Memory Dysfunction and Anxiety Behaviors through Upregulating Glutamatergic Transporters in the Nucleus Accumbens of Mice Repeatedly Exposed to Khat Extract.
Amal O Arab, Fawaz Alasmari, Awatif B Albaker, Hassan A Alhazmi, Alaa Alnoor Alameen, Shakir D AlSharari

Int J Mol Sci· October 2023

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Effects of Chronic Inhalation of Electronic Cigarette Vapor Containing Nicotine on Neurobehaviors and Pre/Postsynaptic Neuron Markers.
Fawaz Alasmari, Farraj M Alotibi, Faleh Alqahtani, Tahani K Alshammari, Aban A Kadi, Shakir D Alsharari

Toxics· June 2022

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Regional functional and structural abnormalities within the aorta as a potential driver of vascular disease in metabolic syndrome.
Omar Z Ameer, Ibrahim M Salman, Aiman Y Alwadi, Abderrahman Ouban, Fahmi M Abu-Owaimer, Shakir D AlSharari

Exp Physiol· March 2021

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Mucoadhesive In Situ Rectal Gel Loaded with Rifampicin: Strategy to Improve Bioavailability and Alleviate Liver Toxicity.
Fakhria Al-Joufi, Mohammed Elmowafy, Nabil K Alruwaili, Khalid S Alharbi, Khaled Shalaby, Shakir D Alsharari

Pharmaceutics· March 2021

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Behavioral and Molecular Basis of Cholinergic Modulation of Pain: Focus on Nicotinic Acetylcholine Receptors.
Wisam Toma, Esad Ulker, Mashael Alqasem, Shakir D AlSharari, J Michael McIntosh

Curr Top Behav Neurosci· November 2020

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The α9α10 nicotinic acetylcholine receptors antagonist α-conotoxin RgIA reverses colitis signs in murine dextran sodium sulfate model.
Shakir D AlSharari, Wisam Toma, Hafiz M Mahmood, J Michael McIntosh, M Imad Damaj

Eur J Pharmacol· September 2020

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The Role of Nicotinic Receptors in the Attenuation of Autism-Related Behaviors in a Murine BTBR T + tf/J Autistic Model.
Hafiz M Mahmood, Hesham M Aldhalaan, Tahani K Alshammari, Mashael A Alqasem, Musaad A Alshammari, Shakir D AlSharari

Autism Res· August 2020

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Systemic TNF-α blockade attenuates anxiety and depressive-like behaviors in mice through downregulation of inflammatory signaling in peripheral immune cells.
Musaad A Alshammari, Mohammad R Khan, Hafiz Majid Mahmood, Abdulaziz O Alshehri, Fawaz F Alasmari, Shakir D Alsharari

Saudi Pharm J· May 2020

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Protease activated receptor-2 mediated upregulation of IL-17 receptor signaling on airway epithelial cells is responsible for neutrophilic infiltration during acute exposure of house dust mite allergens in mice.
Ahmed Nadeem, Naif O Al-Harbi, Sheikh F Ahmad, Khalid E Ibrahim, Moureq R Alotaibi, Shakir D Alsharari

Chem Biol Interact· May 2019

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Effect of 25-methoxy hispidol A isolated from Poncirus trifoliate against bacteria-induced anxiety and depression by targeting neuroinflammation, oxidative stress and apoptosis in mice.
Bushra Shal, Adnan Khan, Muhammad Naveed, Naseem Ullah Khan, Ihsan-Ul-Haq, Shakir D AlSharari

Biomed Pharmacother· March 2019

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Inhibition of spleen tyrosine kinase signaling protects against acute lung injury through blockade of NADPH oxidase and IL-17A in neutrophils and γδ T cells respectively in mice.
Ahmed Nadeem, Sheikh F Ahmad, Naif O Al-Harbi, Mohammed M Al-Harbi, Khalid E Ibrahim, Shakir D AlSharari

Int Immunopharmacol· March 2019

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The Possible Role of in Gastric Cancer and Its Management.
Khalid O Alfarouk, Adil H H Bashir, Ahmed N Aljarbou, AbdelRahman M Ramadan, Abdel Khalig Muddathir, Shakir D AlSharari

Front Oncol· February 2019

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