Publications by authors named "Shanthakumar R Tyavanagimatt"

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A potent Lassa virus antiviral targets an arenavirus virulence determinant.
Ikenna G Madu, Megan Files, Dima N Gharaibeh, Amy L Moore, Kie-Hoon Jung, Shanthakumar R Tyavanagimatt

PLoS Pathog· December 2018

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Pharmacokinetics and interspecies allometric scaling of ST-246, an oral antiviral therapeutic for treatment of orthopoxvirus infection.
Adams Amantana, Yali Chen, Shanthakumar R Tyavanagimatt, Kevin F Jones, Robert Jordan

PLoS One· December 2013

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Pharmacokinetic and pharmacodynamic modeling to determine the dose of ST-246 to protect against smallpox in humans.
Janet M Leeds, Frederique Fenneteau, Nathalie H Gosselin, Mohamad-Samer Mouksassi, Nastya Kassir, Shanthakumar R Tyavanagimatt

Antimicrob Agents Chemother· March 2013

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Safety and pharmacokinetics of the anti-orthopoxvirus compound ST-246 following a single daily oral dose for 14 days in human volunteers.
Jarasvech Chinsangaram, Kady M Honeychurch, Shanthakumar R Tyavanagimatt, Janet M Leeds, Tove' C Bolken

Antimicrob Agents Chemother· September 2012

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Pharmacokinetic comparison of a single oral dose of polymorph form i versus form V capsules of the antiorthopoxvirus compound ST-246 in human volunteers.
Jarasvech Chinsangaram, Kady M Honeychurch, Shanthakumar R Tyavanagimatt, Tove' C Bolken, Robert Jordan

Antimicrob Agents Chemother· July 2012

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SAR analysis of a series of acylthiourea derivatives possessing broad-spectrum antiviral activity.
James R Burgeson, Amy L Moore, Jordan K Boutilier, Natasha R Cerruti, Dima N Gharaibeh, Shanthakumar R Tyavanagimatt

Bioorg Med Chem Lett· July 2012

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Comparison of the safety and pharmacokinetics of ST-246® after i.v. infusion or oral administration in mice, rabbits and monkeys.
Yali Chen, Adams Amantana, Shanthakumar R Tyavanagimatt, Daniela Zima, X Steven Yan

PLoS One· February 2012

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Safety and pharmacokinetics of the antiorthopoxvirus compound ST-246 following repeat oral dosing in healthy adult subjects.
Robert Jordan, Jarasvech Chinsangaram, Tove' C Bolken, Shanthakumar R Tyavanagimatt, Deborah Tien

Antimicrob Agents Chemother· June 2010

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Single-dose safety and pharmacokinetics of ST-246, a novel orthopoxvirus egress inhibitor.
Robert Jordan, Deborah Tien, Tove' C Bolken, Kevin F Jones, Shanthakumar R Tyavanagimatt

Antimicrob Agents Chemother· May 2008

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