Publications by authors named "Sharat Singh"

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Drug tissue concentration and STAT3 modulation as determinants of tofacitinib response in ulcerative colitis.
Bram Verstockt, Dahham Alsoud, Joep van Oostrom, Sare Verstockt, Jeff Smith, Sujay Singh, Sharat Singh

J Crohns Colitis· May 2025

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Evaluation of a Novel Smart Capsule Bacterial Detection System Device for Diagnosis of Small Intestinal Bacterial Overgrowth.
Shaoying Nikki Lee, Pejman Rahimian, Cheryl Stork, Baharak Moshiree, Mitchell Jones, Sharat Singh

Neurogastroenterol Motil· February 2025

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Anti-TNF nonresponse in ulcerative colitis: correcting for mucosal drug exposure reveals distinct cytokine profiles.
Joep van Oostrom, Jurij Hanzel, Bram Verstockt, Sharat Singh, Jeffrey Smith

J Crohns Colitis· January 2025

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Current Trends in IBD-Development of Mucosal-Based Biomarkers and a Novel Minimally Invasive Recoverable Sampling System.
Yunki Y Yau, Valerie C Wasinger, Robert P Hirten, Emil Chuang, Merodean Huntsman, Sharat Singh

Inflamm Bowel Dis· November 2021

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Development of a Novel Drug Delivery System to Deliver Drugs Directly to the Colonic Mucosa, Resulting in Improved Efficacy and Reduced Systemic Exposure for the Treatment of Ulcerative Colitis.
Merodean Huntsman, Shaoying N Lee, Jack Stylli, Cheryl Stork, Jeff Shimizu, Sharat Singh

Crohns Colitis 360· October 2021

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A novel class of polymeric fluorescent dyes assembled using a DNA synthesizer.
Tracy Matray, Sharat Singh, Hesham Sherif, Kenneth Farber, Erin Kwang

PLoS One· January 2021

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Tumor necrosis factor-mediated disposition of infliximab in ulcerative colitis patients.
Sophie E Berends, Tamara J van Steeg, Maurice J Ahsman, Sharat Singh, Johannan F Brandse

J Pharmacokinet Pharmacodyn· December 2019

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Correction: HER2-Overexpressing Breast Cancers Amplify FGFR Signaling upon Acquisition of Resistance to Dual Therapeutic Blockade of HER2.
Ariella B Hanker, Joan T Garrett, Mónica Valeria Estrada, Preston D Moore, Paula González Ericsson, Sharat Singh

Clin Cancer Res· February 2019

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Evolution of cytokines and inflammatory biomarkers during infliximab induction therapy and the impact of inflammatory burden on primary response in patients with Crohn's disease.
Thomas Billiet, Isabelle Cleynen, Vera Ballet, Karolien Claes, Fred Princen, Sharat Singh

Scand J Gastroenterol· October 2017

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HER2-Overexpressing Breast Cancers Amplify FGFR Signaling upon Acquisition of Resistance to Dual Therapeutic Blockade of HER2.
Ariella B Hanker, Joan T Garrett, Mónica Valeria Estrada, Preston D Moore, Paula González Ericsson, Sharat Singh

Clin Cancer Res· August 2017

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A clinically feasible multiplex proteomic immunoassay as a novel functional diagnostic for pancreatic ductal adenocarcinoma.
Kian-Huat Lim, Emma Langley, Feng Gao, Jingqin Luo, Lin Li, Sharat Singh

Oncotarget· April 2017

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Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells.
Albert Bosch-Vilaró, Bart Jacobs, Valentina Pomella, Layka Abbasi Asbagh, Richard Kirkland, Sharat Singh

Oncotarget· January 2017

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Stratified Medicine: Maximizing Clinical Benefit by Biomarker-Driven Health Care.
Sharat Singh

Nestle Nutr Inst Workshop Ser· October 2016

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Commensal-Specific CD4(+) Cells From Patients With Crohn's Disease Have a T-Helper 17 Inflammatory Profile.
Elisabeth Calderón-Gómez, Helena Bassolas-Molina, Rut Mora-Buch, Isabella Dotti, Núria Planell, Sharat Singh

Gastroenterology· September 2016

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Antibodies to adalimumab are associated with future inflammation in Crohn's patients receiving maintenance adalimumab therapy: a post hoc analysis of the Karmiris trial.
Filip Baert, Venkateswarlu Kondragunta, Steven Lockton, Niels Vande Casteele, Scott Hauenstein, Sharat Singh

Gut· July 2016

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The association of tissue anti-TNF drug levels with serological and endoscopic disease activity in inflammatory bowel disease: the ATLAS study.
Andres J Yarur, Anjali Jain, Daniel A Sussman, Jamie S Barkin, Maria A Quintero, Sharat Singh

Gut· February 2016

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Pharmacokinetic Features and Presence of Antidrug Antibodies Associate With Response to Infliximab Induction Therapy in Patients With Moderate to Severe Ulcerative Colitis.
Johannan F Brandse, Ron A Mathôt, Desiree van der Kleij, Theo Rispens, Yaël Ashruf, Sharat Singh

Clin Gastroenterol Hepatol· February 2016

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Higher Adalimumab Levels Are Associated with Histologic and Endoscopic Remission in Patients with Crohn's Disease and Ulcerative Colitis.
Andres J Yarur, Anjali Jain, Scott I Hauenstein, Maria A Quintero, Jamie S Barkin, Sharat Singh

Inflamm Bowel Dis· February 2016

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A Matrix-based Model Predicts Primary Response to Infliximab in Crohn's Disease.
Thomas Billiet, Konstantinos Papamichael, Magali de Bruyn, Bram Verstockt, Isabelle Cleynen, Sharat Singh

J Crohns Colitis· December 2015

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The relationship between infliximab concentrations, antibodies to infliximab and disease activity in Crohn's disease.
Niels Vande Casteele, Reena Khanna, Barrett G Levesque, Larry Stitt, G Y Zou, Sharat Singh

Gut· October 2015

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Low EGFR/MET ratio is associated with resistance to EGFR inhibitors in non-small cell lung cancer.
Silvia Park, Emma Langley, Jong-Mu Sun, Steve Lockton, Jin Seok Ahn, Sharat Singh

Oncotarget· October 2015

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Immunogenicity to infliximab is associated with HLA-DRB1.
Thomas Billiet, Niels Vande Casteele, Thomas Van Stappen, Fred Princen, Sharat Singh

Gut· August 2015

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Long-term outcome of patients with Crohn's disease who discontinued infliximab therapy upon clinical remission.
Konstantinos Papamichael, Niels Vande Casteele, Ann Gils, Sophie Tops, Scott Hauenstein, Sharat Singh

Clin Gastroenterol Hepatol· June 2015

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Concentrations of 6-thioguanine nucleotide correlate with trough levels of infliximab in patients with inflammatory bowel disease on combination therapy.
Andres J Yarur, Maddie J Kubiliun, Frank Czul, Daniel A Sussman, Maria A Quintero, Sharat Singh

Clin Gastroenterol Hepatol· June 2015

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Antibodies to infliximab are associated with lower infliximab levels and increased likelihood of surgery in pediatric IBD.
Naamah L Zitomersky, Benjamin J Atkinson, Kerri Fournier, Paul D Mitchell, Julia Bender Stern, Sharat Singh

Inflamm Bowel Dis· February 2015

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