Publications by authors named "Sharon A Singh"

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p27Kip1 regulates γ-globin production.
Ginette Balbin-Cuesta, Claire Drysdale, Claire Kerpet, Lei Yu, Greggory Myers, Sharon A Singh

Blood· December 2025

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Novel, potent, and orally bioavailable LSD1 inhibitors induce fetal hemoglobin synthesis in a sickle cell disease mouse model.
Yu Wang, Lei Yu, Kaiwen Deng, Mathivanan Packiarajan, Angelo Aguilar, Sharon A Singh

Blood· July 2025

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A lipid metabolism defect is an underlying contributor to Diamond Blackfan anemia syndrome.
Kaiwen Deng, Yu Wang, Joseph C Min, Xiaofang Liu, Greggory Myers, Sharon A Singh

bioRxiv· May 2025

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A genome-wide screen identifies genes required for erythroid differentiation.
Greggory Myers, Ann Friedman, Lei Yu, Narges Pourmandi, Claire Kerpet, Sharon A Singh

Nat Commun· April 2025

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TR4 and BCL11A repress γ-globin transcription via independent mechanisms.
Yu Wang, Greggory Myers, Lei Yu, Kaiwen Deng, Ginette Balbin-Cuesta, Sharon A Singh

Blood· December 2024

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Murine erythroid differentiation kinetics in vivo under normal and anemic stress conditions.
Greggory Myers, Yu Wang, Qing Wang, Ann Friedman, Alejandra Sanchez-Martinez, Sharon A Singh

Blood Adv· October 2023

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Mexiletine: An adjuvant option for refractory pain in patients with sickle cell disease and comorbid autism spectrum disorder.
Nour K Kadouh, Stacy Lang, Mark Shamoun, Eric L Scott, Sharon A Singh

Pediatr Blood Cancer· August 2022

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Identification of novel γ-globin inducers among all potential erythroid druggable targets.
Lei Yu, Greggory Myers, Emily Schneider, Yu Wang, Raven Mathews, Sharon A Singh

Blood Adv· June 2022

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Buprenorphine for Chronic Pain in a Pediatric Patient With Sickle-Cell Disease.
Madison Irwin, William Gunther, Patricia Keefer, D'Anna Saul, Sharon A Singh

J Pain Symptom Manage· November 2021

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An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation.
Lei Yu, Greggory Myers, Chia-Jui Ku, Emily Schneider, Yu Wang, Sharon A Singh

Blood· November 2021

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A new murine Rpl5 (uL18) mutation provides a unique model of variably penetrant Diamond-Blackfan anemia.
Lei Yu, Philippe Lemay, Alexander Ludlow, Marie-Claude Guyot, Morgan Jones, Sharon A Singh

Blood Adv· October 2021

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The Use of B-Cell Polysome Profiling to Validate Novel RPL5 (uL18) and RPL26 (uL24) Variants in Diamond-Blackfan Anemia.
Alexander Ludlow, Nicholas George, Megan Glassford, Katie Udenberg, Mark C Hannibal, Sharon A Singh

J Pediatr Hematol Oncol· April 2021

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Epigenetic activities in erythroid cell gene regulation.
Yu Wang, Lei Yu, James Douglas Engel, Sharon A Singh

Semin Hematol· January 2021

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What is the future of patient-reported outcomes in sickle-cell disease?
Sharon A Singh, Nitya Bakshi, Prashant Mahajan, Claudia R Morris

Expert Rev Hematol· November 2020

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Hb Adana (HBA2 or HBA1: c.179G > A) and alpha thalassemia: Genotype-phenotype correlation.
Sharon A Singh, Susmita Sarangi, Abena Appiah-Kubi, Peihong Hsu, W Byron Smith

Pediatr Blood Cancer· September 2018

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Pomalidomide reverses γ-globin silencing through the transcriptional reprogramming of adult hematopoietic progenitors.
Brian M Dulmovits, Abena O Appiah-Kubi, Julien Papoin, John Hale, Mingzhu He, Sharon A Singh

Blood· March 2016

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p53-Independent cell cycle and erythroid differentiation defects in murine embryonic stem cells haploinsufficient for Diamond Blackfan anemia-proteins: RPS19 versus RPL5.
Sharon A Singh, Tracie A Goldberg, Adrianna L Henson, Sehba Husain-Krautter, Abdallah Nihrane

PLoS One· October 2014

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Diminutive somatic deletions in the 5q region lead to a phenotype atypical of classical 5q- syndrome.
Adrianna Vlachos, Jason E Farrar, Eva Atsidaftos, Ellen Muir, Anupama Narla, Sharon A Singh

Blood· October 2013

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Breast cancer in a case of Shwachman Diamond syndrome.
Sharon A Singh, Adrianna Vlachos, Nora J Morgenstern, Ihsane Ouansafi, Wan Ip

Pediatr Blood Cancer· November 2012

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Resolution of chronic hypoxemia in pediatric sickle cell patients after treatment with hydroxyurea.
Sharon A Singh, Anastassios C Koumbourlis, Banu Aygun

Pediatr Blood Cancer· June 2008

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