Publications by authors named "Sharon Cheetham"

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Novel, non-nitrocatechol catechol-O-methyltransferase inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility.
Spencer Byers, Ingrid P Buchler, Michael DePasquale, Helen L Rowley, Rajiv S Kulkarni, Sharon C Cheetham

Psychopharmacology (Berl)· September 2020

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Discovery of Highly Selective Inhibitors of Calmodulin-Dependent Kinases That Restore Insulin Sensitivity in the Diet-Induced Obesity Mouse Model.
Christophe Fromont, Alessio Atzori, Divneet Kaur, Lubna Hashmi, Graziella Greco, Sharon C Cheetham

J Med Chem· July 2020

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Effects of corticosterone within the hypothalamic arcuate nucleus on food intake and body weight in male rats.
Chioma Izzi-Engbeaya, Yue Ma, Niki W Buckley, Risheka Ratnasabapathy, Errol Richardson, Sharon Cheetham

Mol Metab· June 2020

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Histologic Characterization of Retina Neuroglia Modifications in Diabetic Zucker Diabetic Fatty Rats.
Ivan Fernandez-Bueno, Robert Jones, Laura Soriano-Romaní, Antonio López-García, Orla Galvin, Sharon Cheetham

Invest Ophthalmol Vis Sci· September 2017

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Dopamine and μ-opioid receptor dysregulation in the brains of binge-eating female rats - possible relevance in the psychopathology and treatment of binge-eating disorder.
David J Heal, Michelle Hallam, Michael Prow, Jane Gosden, Sharon Cheetham

J Psychopharmacol· June 2017

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A sustained release formulation of novel quininib-hyaluronan microneedles inhibits angiogenesis and retinal vascular permeability in vivo.
Orla Galvin, Akshay Srivastava, Oliver Carroll, Rajiv Kulkarni, Steve Dykes, Sharon Cheetham

J Control Release· July 2016

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Characterisation of pain responses in the high fat diet/streptozotocin model of diabetes and the analgesic effects of antidiabetic treatments.
Frederika Maria Byrne, Sharon Cheetham, Steven Vickers, Victoria Chapman

J Diabetes Res· October 2015

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Combination of the sodium-glucose cotransporter-2 inhibitor empagliflozin with orlistat or sibutramine further improves the body-weight reduction and glucose homeostasis of obese rats fed a cafeteria diet.
Steven P Vickers, Sharon C Cheetham, Katie R Headland, Keith Dickinson, Rolf Grempler

Diabetes Metab Syndr Obes· July 2014

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Effect of linagliptin, alone and in combination with voglibose or exendin-4, on glucose control in male ZDF rats.
Robert B Jones, Steven P Vickers, Sharon C Cheetham, Katie R Headland, Michael Mark

Eur J Pharmacol· April 2014

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Metabolic consequences of antipsychotic therapy: preclinical and clinical perspectives on diabetes, diabetic ketoacidosis, and obesity.
David J Heal, Jane Gosden, Helen C Jackson, Sharon C Cheetham, Sharon L Smith

Handb Exp Pharmacol· April 2013

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Effects of the DPP-4 inhibitor, linagliptin, in diet-induced obese rats: a comparison in naive and exenatide-treated animals.
Steven P Vickers, Sharon C Cheetham, Gareth D Birmingham, Helen L Rowley, Katie R Headland

Clin Lab· October 2012

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Some cannabinoid receptor ligands and their distomers are direct-acting openers of SUR1 K(ATP) channels.
Christopher J Lynch, Qing Zhou, Show-Ling Shyng, David J Heal, Sharon C Cheetham

Am J Physiol Endocrinol Metab· March 2012

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The utility of animal models to evaluate novel anti-obesity agents.
Steven P Vickers, Helen C Jackson, Sharon C Cheetham

Br J Pharmacol· October 2011

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Synthesis and SAR of 4-aryl-1-(indazol-5-yl)pyridin-2(1H)ones as MCH-1 antagonists for the treatment of obesity.
Mark Hadden, Dustin M Deering, Alan J Henderson, Matthew D Surman, Michele Luche, Sharon Cheetham

Bioorg Med Chem Lett· December 2010

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Tetrahydrocarboline analogs as MCH-1 antagonists.
Alan J Henderson, Dustin Deering, James F Grabowski, Mark Hadden, Xiaowu Jiang, Sharon Cheetham

Bioorg Med Chem Lett· December 2010

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5-(pyridinon-1-yl)indazoles and 5-(furopyridinon-5-yl)indazoles as MCH-1 antagonists.
Matthew D Surman, Emily E Freeman, James F Grabowski, Mark Hadden, Alan J Henderson, Sharon Cheetham

Bioorg Med Chem Lett· December 2010

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Prokineticin 2 is a hypothalamic neuropeptide that potently inhibits food intake.
James V Gardiner, Attia Bataveljic, Neekhil A Patel, Gavin A Bewick, Debabrata Roy, Sharon Cheetham

Diabetes· February 2010

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Receptor occupancy and brain free fraction.
Jeanette Watson, Sara Wright, Adam Lucas, Kirsten L Clarke, Jean Viggers, Sharon Cheetham

Drug Metab Dispos· April 2009

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GPR39 signaling is stimulated by zinc ions but not by obestatin.
Birgitte Holst, Kristoffer L Egerod, Enrico Schild, Steve P Vickers, Sharon Cheetham

Endocrinology· January 2007

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MTSEA prevents ligand binding to the human melanocortin-4 receptor by modification of cysteine 130 in transmembrane helix 3.
Alan Cox, Dan Donnelly, Manminder Kaur, Sharon C Cheetham, Victor B Cockcroft

FEBS Lett· January 2005

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The monoamine reuptake inhibitor BTS 74 398 fails to evoke established dyskinesia but does not synergise with levodopa in MPTP-treated primates.
Matthew J Hansard, Lance A Smith, Michael J Jackson, Sharon C Cheetham, Peter Jenner

Mov Disord· January 2004

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Dopamine, but not norepinephrine or serotonin, reuptake inhibition reverses motor deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates.
Matthew J Hansard, Lance A Smith, Michael J Jackson, Sharon C Cheetham, Peter Jenner

J Pharmacol Exp Ther· December 2002

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Dopamine reuptake inhibition and failure to evoke dyskinesia in MPTP-treated primates.
Matthew J Hansard, Lance A Smith, Michael J Jackson, Sharon C Cheetham, Peter Jenner

Eur J Pharmacol· September 2002

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