Publications by authors named "Sharon Engel"

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Zalsupindole is a Nondissociative, Nonhallucinogenic Neuroplastogen with Therapeutic Effects Comparable to Ketamine and Psychedelics.
Rajiv Agrawal, Daniel Gillie, Alison Mungenast, Milan Chytil, Sharon Engel

ACS Chem Neurosci· November 2025

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Molecular design of a therapeutic LSD analogue with reduced hallucinogenic potential.
Jeremy R Tuck, Lee E Dunlap, Yara A Khatib, Cassandra J Hatzipantelis, Sammy Weiser Novak, Sharon Engel

Proc Natl Acad Sci U S A· April 2025

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Longitudinal two-photon imaging in somatosensory cortex of behaving mice reveals dendritic spine formation enhancement by subchronic administration of low-dose ketamine.
Evgeny Pryazhnikov, Ekaterina Mugantseva, Plinio Casarotto, Julia Kolikova, Senem Merve Fred, Sharon Engel

Sci Rep· April 2018

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Pharmacological evaluation of a novel phosphodiesterase 10A inhibitor in models of antipsychotic activity and cognition.
Philip G Jones, Michael C Hewitt, John E Campbell, Maria S Quinton, Sharon Engel

Pharmacol Biochem Behav· August 2015

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Differential BDNF responses of triple versus dual reuptake inhibition in neuronal and astrocytoma cells as well as in rat hippocampus and prefrontal cortex.
Jos Prickaerts, Jochen De Vry, Janneke Boere, Gunter Kenis, Maria S Quinton, Sharon Engel

J Mol Neurosci· September 2012

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Synthesis and pharmacological characterization of bicyclic triple reuptake inhibitor 3-aryl octahydrocyclopenta[c]pyrrole analogues.
Liming Shao, Michael C Hewitt, Scott C Malcolm, Fengjiang Wang, Jianguo Ma, Sharon R Engel

J Med Chem· August 2011

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Discovery of N-methyl-1-(1-phenylcyclohexyl)methanamine, a novel triple serotonin, norepinephrine, and dopamine reuptake inhibitor.
Liming Shao, Michael C Hewitt, Fengjiang Wang, Scott C Malcolm, Jianguo Ma, Sharon R Engel

Bioorg Med Chem Lett· March 2011

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Discovery of N-methyl-1-(1-phenylcyclohexyl)ethanamine, a novel triple serotonin, norepinephrine and dopamine reuptake inhibitor.
Liming Shao, Michael C Hewitt, Fengjiang Wang, Scott C Malcolm, Jianguo Ma, Sharon R Engel

Bioorg Med Chem Lett· March 2011

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Synthesis and pharmacological evaluation of 4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalenyl amines as triple reuptake inhibitors.
Liming Shao, Fengjiang Wang, Scott C Malcolm, Jianguo Ma, Michael C Hewitt, Sharon R Engel

Bioorg Med Chem· January 2011

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The anterior cingulate ERK pathway contributes to regulation of behavioral excitement and hedonic activity.
Thomas K Creson, Yanlei Hao, Sharon Engel, Yi Shen, Anahita Hamidi

Bipolar Disord· June 2009

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Sterically bulky tris(triazolyl)borate ligands as water-soluble analogues of tris(pyrazolyl)borate.
Finith E Jernigan, Nathan A Sieracki, Michael T Taylor, Aaron S Jenkins, Sharon E Engel

Inorg Chem· January 2007

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Satisfaction with end-of-life care for nursing home residents with advanced dementia.
Sharon E Engel, Dan K Kiely, Susan L Mitchell

J Am Geriatr Soc· October 2006

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Design of a genome-wide siRNA library using an artificial neural network.
Dieter Huesken, Joerg Lange, Craig Mickanin, Jan Weiler, Fred Asselbergs, Sharon Engel

Nat Biotechnol· August 2005

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Unusual alternative splicing within the human kallikrein genes KLK2 and KLK3 gives rise to novel prostate-specific proteins.
Anat David, Nicola Mabjeesh, Idit Azar, Sharon Biton, Sharon Engel

J Biol Chem· May 2002

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