Publications by authors named "Sharoon Akhtar"

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A STAT1-GBP1 axis modulates epithelial proliferation in postpartum breast tissue by repressing CDKI expression.
Joshua W Ogony, Laura M Pacheco-Spann, Amanda Arnold, Jennifer V Cabezas, Nicole Cruz-Reyes, Sharoon Akhtar

Breast Cancer Res· September 2025

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Novel tumor-targeted liposomes comprised of an MDM2 antagonist plus proteasome inhibitor display anti-tumor activity in a xenograft model of bortezomib-resistant Waldenstrom macroglobulinemia.
Vijay Sagar Madamsetty, Aneel Paulus, Sharoon Akhtar, Alak Manna, Harikrishna Reddy Rachamalla

Leuk Lymphoma· October 2020

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Targeting CD38 Enhances the Antileukemic Activity of Ibrutinib in Chronic Lymphocytic Leukemia.
Alak Manna, Sonikpreet Aulakh, Prachi Jani, Salman Ahmed, Sharoon Akhtar

Clin Cancer Res· July 2019

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Targeting CD38 with daratumumab is lethal to Waldenström macroglobulinaemia cells.
Aneel Paulus, Alak Manna, Sharoon Akhtar, Shumail M Paulus, Mayank Sharma

Br J Haematol· October 2018

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Synthesis, Computational Docking Study, and Biological Evaluation of a Library of Heterocyclic Curcuminoids with Remarkable Antitumor Activity.
Kenneth K Laali, William J Greves, Angela T Zwarycz, Sebastian J Correa Smits, Frederick J Troendle, Sharoon Akhtar

ChemMedChem· September 2018

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Corrigendum: The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells.
Xin Wang, Magdalena Mazurkiewicz, Ellin-Kristina Hillert, Maria Hägg Olofsson, Stefan Pierrou, Sharoon Akhtar

Sci Rep· July 2016

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The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells.
Xin Wang, Magdalena Mazurkiewicz, Ellin-Kristina Hillert, Maria Hägg Olofsson, Stefan Pierrou, Sharoon Akhtar

Sci Rep· June 2016

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Immunophenotyping of Waldenströms macroglobulinemia cell lines reveals distinct patterns of surface antigen expression: potential biological and therapeutic implications.
Aneel Paulus, Kasyapa S Chitta, Paul K Wallace, Pooja P Advani, Sharoon Akhtar

PLoS One· March 2016

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Targeted inhibition of the deubiquitinating enzymes, USP14 and UCHL5, induces proteotoxic stress and apoptosis in Waldenström macroglobulinaemia tumour cells.
Kasyapa Chitta, Aneel Paulus, Sharoon Akhtar, Maja Kristin K Blake, Thomas R Caulfield

Br J Haematol· May 2015

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AT-101 downregulates BCL2 and MCL1 and potentiates the cytotoxic effects of lenalidomide and dexamethasone in preclinical models of multiple myeloma and Waldenström macroglobulinaemia.
Aneel Paulus, Kasyapa Chitta, Sharoon Akhtar, David Personett, Kena C Miller

Br J Haematol· February 2014

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