Publications by authors named "Shaughn Bell"

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Human iPSC-Derived Mononuclear Phagocytes Improve Cognition and Neural Health across Multiple Mouse Models of Aging and Alzheimer's Disease.
V Alexandra Moser, Luz Jovita Dimas-Harms, Rachel M Lipman, Jake Inzalaco, Shaughn Bell

Adv Sci (Weinh)· November 2025

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An organ-chip model of sporadic ALS using iPSC-derived spinal cord motor neurons and an integrated blood-brain-like barrier.
Deepti Lall, Michael J Workman, Samuel Sances, Briana N Ondatje, Shaughn Bell

Cell Stem Cell· July 2025

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Mitofusin 1 overexpression rescues the abnormal mitochondrial dynamics caused by the Mitofusin 2 K357T mutation in vitro.
Filippos Stavropoulos, Elena Georgiou, Natasa Schiza, Shaughn Bell, Robert H Baloh

J Peripher Nerv Syst· September 2023

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Organ-Chips Enhance the Maturation of Human iPSC-Derived Dopamine Neurons.
Maria G Otero, Shaughn Bell, Alexander H Laperle, George Lawless, Zachary Myers

Int J Mol Sci· September 2023

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Human iPSC-derived neural progenitor cells secreting GDNF provide protection in rodent models of ALS and retinal degeneration.
Alexander H Laperle, V Alexandra Moser, Pablo Avalos, Bin Lu, Amanda Wu, Shaughn Bell

Stem Cell Reports· August 2023

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Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.
Wouter van Rheenen, Rick A A van der Spek, Mark K Bakker, Joke J F A van Vugt, Paul J Hop, Isabella Fogh, Shaughn Bell

Nat Genet· March 2022

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Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.
Wouter van Rheenen, Rick A A van der Spek, Mark K Bakker, Joke J F A van Vugt, Paul J Hop, Isabella Fogh, Shaughn Bell

Nat Genet· December 2021

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C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation.
Deepti Lall, Ileana Lorenzini, Thomas A Mota, Shaughn Bell, Thomas E Mahan

Neuron· July 2021

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Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model.
Yueqin Zhou, Sharon Carmona, A K M G Muhammad, Shaughn Bell, Jesse Landeros

J Clin Invest· January 2021

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C9orf72 in myeloid cells suppresses STING-induced inflammation.
Madelyn E McCauley, Jacqueline Gire O'Rourke, Alberto Yáñez, Janet L Markman, Ritchie Ho, Shaughn Bell

Nature· September 2020

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Comparison of three congruent patient-specific cell types for the modelling of a human genetic Schwann-cell disorder.
Bipasha Mukherjee-Clavin, Ruifa Mi, Barbara Kern, In Young Choi, Hotae Lim, Shaughn Bell

Nat Biomed Eng· July 2019

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Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model.
Yueqin Zhou, Sharon Carmona, A K M G Muhammad, Shaughn Bell, Jesse Landeros

J Clin Invest· March 2019

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Cell transplantation strategies for acquired and inherited disorders of peripheral myelin.
A K M G Muhammad, Kevin Kim, Irina Epifantseva, Arwin Aghamaleky-Sarvestany, Megan E Simpkinson, Shaughn Bell

Ann Clin Transl Neurol· February 2018

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C9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD.
Jacqueline G O'Rourke, Laurent Bogdanik, A K M G Muhammad, Tania F Gendron, Kevin J Kim, Shaughn Bell

Neuron· December 2015

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TDP-43 activates microglia through NF-κB and NLRP3 inflammasome.
Weihua Zhao, David R Beers, Shaughn Bell, Jinghong Wang, Shixiang Wen

Exp Neurol· November 2015

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Prion-like nuclear aggregation of TDP-43 during heat shock is regulated by HSP40/70 chaperones.
Maria Udan-Johns, Rocio Bengoechea, Shaughn Bell, Jieya Shao, Marc I Diamond

Hum Mol Genet· January 2014

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Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion.
Dhruv Sareen, Jacqueline G O'Rourke, Pratap Meera, A K M G Muhammad, Sharday Grant, Shaughn Bell

Sci Transl Med· October 2013

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Exome sequencing reveals DNAJB6 mutations in dominantly-inherited myopathy.
Matthew B Harms, R Brian Sommerville, Peggy Allred, Shaughn Bell, Duanduan Ma

Ann Neurol· March 2012

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Interaction with polyglutamine aggregates reveals a Q/N-rich domain in TDP-43.
Rodrigo A Fuentealba, Maria Udan, Shaughn Bell, Iga Wegorzewska, Jieya Shao

J Biol Chem· August 2010

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TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration.
Iga Wegorzewska, Shaughn Bell, Nigel J Cairns, Timothy M Miller, Robert H Baloh

Proc Natl Acad Sci U S A· November 2009

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