Publications by authors named "Shaun Brothers"

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Identification of targetable epigenetic vulnerabilities for uveal melanoma.
Gulum Yenisehirli, Sebastian Borges, Steffanie S Braun, Ashley N Zuniga, Gabriela I Quintana, Shaun P Brothers

Cell Death Dis· December 2025

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Bruton's tyrosine kinase inhibition re-sensitizes multidrug-resistant DLBCL tumors driven by BCL10 gain-of-function mutants to venetoclax.
Caroline A Coughlin, Dhanvantri Chahar, Marianna Lekakis, Abdessamad A Youssfi, Lingxiao Li, Shaun Brothers

Blood Cancer J· February 2025

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Activating transcription factor 4 regulates hypoxia inducible factor 1α in chronic hypoxia in pancreatic cancer cells.
Nancy T Chee, Candace H Carriere, Zachary Miller, Scott Welford, Shaun P Brothers

Oncol Rep· January 2023

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Functional Drug Screening of Small Molecule Inhibitors of Epigenetic Modifiers in Refractory AML Patients.
Jessica L Dennison, Hassan Al-Ali, Claude-Henry Volmar, Shaun Brothers, Justin Watts

Cancers (Basel)· August 2022

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Safety and pharmacokinetics of a highly bioavailable resveratrol preparation (JOTROL ).
Christopher Kemper, Dariush Benham, Shaun Brothers, Claes Wahlestedt, Claude-Henry Volmar

AAPS Open· June 2022

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JOTROL, a Novel Formulation of Resveratrol, Shows Beneficial Effects in the 3xTg-AD Mouse Model.
Jessica L Dennison, Claude-Henry Volmar, Farzaneh Modarresi, Danbing Ke, James Wang, Shaun P Brothers

J Alzheimers Dis· April 2022

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A novel strategy for combination of clofarabine and pictilisib is synergistic in gastric cancer.
Shayan Khalafi, Shoumin Zhu, Rimpi Khurana, Ines Lohse, Silvia Giordano, Shaun P Brothers

Transl Oncol· January 2022

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Erratum to: JOTROL, a Novel Formulation of Resveratrol, Shows Beneficial Effects in the 3xTg-AD Mouse Model.
Jessica L Dennison, Claude-Henry Volmar, Farzaneh Modarresi, Danbing Ke, James Wang, Shaun P Brothers

J Alzheimers Dis· January 2022

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Dual Screen for Efficacy and Toxicity Identifies HDAC Inhibitor with Distinctive Activity Spectrum for BAP1-Mutant Uveal Melanoma.
Jeffim N Kuznetsoff, Dawn A Owens, Andy Lopez, Daniel A Rodriguez, Nancy T Chee, Shaun P Brothers

Mol Cancer Res· February 2021

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Pathogenesis and Treatment of Pancreatic Cancer Related Pain.
Ines Lohse, Shaun P Brothers

Anticancer Res· April 2020

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BET Bromodomain Inhibitors Which Permit Treg Function Enable a Combinatorial Strategy to Suppress GVHD in Pre-clinical Allogeneic HSCT.
Sabrina N Copsel, Casey O Lightbourn, Henry Barreras, Ines Lohse, Dietlinde Wolf, Shaun P Brothers

Front Immunol· October 2019

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Ovarian Cancer Treatment Stratification Using Drug Sensitivity Testing.
Ines Lohse, Diana J Azzam, Hassan Al-Ali, Claude-Henry Volmar, Shaun P Brothers

Anticancer Res· August 2019

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Vitamin C supplementation expands the therapeutic window of BETi for triple negative breast cancer.
Sushmita Mustafi, Vladimir Camarena, Rehana Qureshi, Hyunho Yoon, Claude-Henry Volmar, Shaun P Brothers

EBioMedicine· May 2019

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HDAC Inhibitors Induce Expression and Promote Neurite Outgrowth in Human Neural Progenitor Cells-Derived Neurons.
Amir Bagheri, Parham Habibzadeh, Seyedeh Fatemeh Razavipour, Claude-Henry Volmar, Nancy T Chee, Shaun P Brothers

Int J Mol Sci· March 2019

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mRNA-to-protein translation in hypoxia.
Nancy T Chee, Ines Lohse, Shaun P Brothers

Mol Cancer· March 2019

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Ex vivo drug sensitivity testing as a means for drug repurposing in esophageal adenocarcinoma.
Ines Lohse, Hassan Al-Ali, Claude-Henry Volmar, Annamil D Alvarez Trotta, Shaun P Brothers

PLoS One· February 2019

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Precision medicine in the treatment stratification of AML patients: challenges and progress.
Ines Lohse, Kurt Statz-Geary, Shaun P Brothers, Claes Wahlestedt

Oncotarget· December 2018

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EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia.
Andrea L Johnstone, Jiaqi J O'Reilly, Annika J Patel, Zhihong Guo, Nadja S Andrade, Shaun P Brothers

Neurobiol Dis· November 2018

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Inhibition of HDAC3 reverses Alzheimer's disease-related pathologies in vitro and in the 3xTg-AD mouse model.
Karolina J Janczura, Claude-Henry Volmar, Gregory C Sartor, Sunil J Rao, Natalie R Ricciardi, Shaun P Brothers

Proc Natl Acad Sci U S A· November 2018

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Naturally occurring compounds as pancreatic cancer therapeutics.
Ines Lohse, Erin Wildermuth, Shaun P Brothers

Oncotarget· October 2018

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Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study.
Ronan T Swords, Diana Azzam, Hassan Al-Ali, Ines Lohse, Claude-Henry Volmar, Shaun P Brothers

Leuk Res· January 2018

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Vitamin C Sensitizes Melanoma to BET Inhibitors.
Sushmita Mustafi, Vladimir Camarena, Claude-Henry Volmar, Tyler C Huff, David W Sant, Shaun P Brothers

Cancer Res· January 2018

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M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer's disease genes and improving memory.
Claude-Henry Volmar, Hasib Salah-Uddin, Karolina J Janczura, Paul Halley, Guerline Lambert, Shaun P Brothers

Proc Natl Acad Sci U S A· October 2017

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Oxytocin and social functioning.
Candace Jones, Ingrid Barrera, Shaun Brothers, Robert Ring, Claes Wahlestedt

Dialogues Clin Neurosci· June 2017

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The nociceptin/orphanin FQ receptor agonist SR-8993 as a candidate therapeutic for alcohol use disorders: validation in rat models.
Abdul Maruf Asif Aziz, Shaun Brothers, Gregory Sartor, Lovisa Holm, Markus Heilig

Psychopharmacology (Berl)· October 2016

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