Publications by authors named "Shaun D McCullough"

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Sex modifies response to ozone and nitrogen dioxide: a controlled human exposure study.
Jairus C Pulczinski, Ana G Rappold, Robert B Devlin, David Diaz-Sanchez, Emma C Bowers, Shaun D McCullough

Inhal Toxicol· November 2025

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Wildfire-relevant woodsmoke and extracellular vesicles (EVs): Alterations in EV proteomic signatures involved in extracellular matrix degradation and tissue injury in airway organotypic models.
Eva C M Vitucci, Celeste K Carberry, Alexis Payton, Laura E Herring, Angie L Mordant, Shaun D McCullough

Environ Res· January 2025

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New approach methodologies (NAMs) for the assessment of cleaning products for respiratory irritation: workshop report.
Lynne T Haber, Mark A Bradley, Amanda N Buerger, Holger Behrsing, Sabina Burla, Shaun D McCullough

Front Toxicol· October 2024

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Trust your gut: Establishing confidence in gastrointestinal models - An overview of the state of the science and contexts of use.
Susan Debad, David Allen, Omari Bandele, Colin Bishop, Michaela Blaylock, Shaun D McCullough

ALTEX· July 2024

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Epithelial MAPK signaling directs endothelial NRF2 signaling and IL-8 secretion in a tri-culture model of the alveolar-microvascular interface following diesel exhaust particulate (DEP) exposure.
Eva C M Vitucci, Alysha E Simmons, Elizabeth M Martin, Shaun D McCullough

Part Fibre Toxicol· March 2024

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Liquid application dosing alters the physiology of air-liquid interface (ALI) primary human bronchial epithelial cell/lung fibroblast co-cultures and testing relevant endpoints.
Nicholas M Mallek, Elizabeth M Martin, Lisa A Dailey, Shaun D McCullough

Front Toxicol· January 2024

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Characterizing the extracellular vesicle proteomic landscape of the human airway using organotypic multi-cellular models.
Eva C M Vitucci, Celeste K Carberry, Alexis Payton, Laura E Herring, Angie L Mordant, Shaun D McCullough

iScience· November 2023

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Liquid Application Dosing Alters the Physiology of Air-Liquid Interface Primary Bronchial Epithelial Cultures and In vitro Testing Relevant Endpoints.
Nicholas M Mallek, Elizabeth M Martin, Lisa A Dailey, Shaun D McCullough

Res Sq· February 2023

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Ozone Responsive Gene Expression as a Model for Describing Repeat Exposure Response Trajectories and Interindividual Toxicodynamic Variability In Vitro.
Emma C Bowers, Elizabeth M Martin, Annie M Jarabek, David S Morgan, Hannah J Smith, Shaun D McCullough

Toxicol Sci· December 2021

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Exposure Effects Beyond the Epithelial Barrier: Transepithelial Induction of Oxidative Stress by Diesel Exhaust Particulates in Lung Fibroblasts in an Organotypic Human Airway Model.
Samantha C Faber, Nicole A McNabb, Pablo Ariel, Emily R Aungst, Shaun D McCullough

Toxicol Sci· September 2020

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A new cell culture exposure system for studying the toxicity of volatile chemicals at the air-liquid interface.
Jose Zavala, Allen D Ledbetter, David S Morgan, Lisa A Dailey, Earl Puckett, Shaun D McCullough

Inhal Toxicol· March 2019

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Through the Looking Glass: Models for Inhalation Toxicology and Interindividual Variability in the Airway.
Samantha C Faber, Shaun D McCullough

Appl In Vitro Toxicol· June 2018

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ERK1/2 and p38 regulate inter-individual variability in ozone-mediated IL-8 gene expression in primary human bronchial epithelial cells.
Emma C Bowers, Shaun D McCullough, David S Morgan, Lisa A Dailey, David Diaz-Sanchez

Sci Rep· June 2018

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Epigenetic Applications in Adverse Outcome Pathways and Environmental Risk Evaluation.
Michelle M Angrish, Patrick Allard, Shaun D McCullough, Ingrid L Druwe, Lisa Helbling Chadwick

Environ Health Perspect· April 2018

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Effects of Simulated Smog Atmospheres in Rodent Models of Metabolic and Immunologic Dysfunction.
Marie McGee Hargrove, Samantha J Snow, Robert W Luebke, Charles E Wood, Jonathan D Krug, Shaun D McCullough

Environ Sci Technol· March 2018

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Application of epigenetic data in human health risk assessment.
Ila L Cote, Shaun D McCullough, Ronald N Hines, John J Vandenberg

Curr Opin Toxicol· November 2017

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Air Pollution and the Epigenome: A Model Relationship for the Exploration of Toxicoepigenetics.
Shaun D McCullough, Radhika Dhingra, Marie C Fortin, David Diaz-Sanchez

Curr Opin Toxicol· October 2017

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Alterations in airway microbiota in patients with PaO2/FiO2 ratio ≤ 300 after burn and inhalation injury.
Dana M Walsh, Shaun D McCullough, Scott Yourstone, Samuel W Jones, Bruce A Cairns

PLoS One· August 2017

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Using Chromatin Immunoprecipitation in Toxicology: A Step-by-Step Guide to Increasing Efficiency, Reducing Variability, and Expanding Applications.
Shaun D McCullough, Doan M On, Emma C Bowers

Curr Protoc Toxicol· May 2017

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Linking the Epigenome with Exposure Effects and Susceptibility: The Epigenetic Seed and Soil Model.
Emma C Bowers, Shaun D McCullough

Toxicol Sci· February 2017

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MicroRNA Biomarkers of Toxicity in Biological Matrices.
Alison H Harrill, Shaun D McCullough, Charles E Wood, Juliette J Kahle, Brian N Chorley

Toxicol Sci· August 2016

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Baseline Chromatin Modification Levels May Predict Interindividual Variability in Ozone-Induced Gene Expression.
Shaun D McCullough, Emma C Bowers, Doan M On, David S Morgan, Lisa A Dailey

Toxicol Sci· March 2016

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Ozone induces a proinflammatory response in primary human bronchial epithelial cells through mitogen-activated protein kinase activation without nuclear factor-κB activation.
Shaun D McCullough, Kelly E Duncan, Samantha M Swanton, Lisa A Dailey, David Diaz-Sanchez

Am J Respir Cell Mol Biol· September 2014

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Reelin is a target of polyglutamine expanded ataxin-7 in human spinocerebellar ataxia type 7 (SCA7) astrocytes.
Shaun D McCullough, Xiaojiang Xu, Sharon Y R Dent, Stefan Bekiranov, Robert G Roeder

Proc Natl Acad Sci U S A· December 2012

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Histone acetylation, acetyltransferases, and ataxia--alteration of histone acetylation and chromatin dynamics is implicated in the pathogenesis of polyglutamine-expansion disorders.
Shaun D McCullough, Patrick A Grant

Adv Protein Chem Struct Biol· May 2011

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